Gene Information

Name : Ddes_1338 (Ddes_1338)
Accession : YP_002479918.1
Strain : Desulfovibrio desulfuricans ATCC 27774
Genome accession: NC_011883
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 1605018 - 1606688 bp
Length : 1671 bp
Strand : -
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: bte:BTH_II1830 salicyl-AMP ligase

DNA sequence : 
ATGCTTTATGCGCGTGATTTGGGGTGGCCACAGGATATTATTAACAAATACCGTGCGGAAGATTATTGGCGCGATGAAAC
GTTCAATACCCTTCTGCAGGATGTTGCCGGGCGCAAGGGAGACTGCATGGCAGTTGTCGATGGCAACGTTCGCCTCACCT
ATGCAGAATTCAAGGAAATGGTTGACAGAATTGCGGGAGGTTTTGCCGCTCTTGGGCTCGGGGCCGGCGACCACGTTGTG
GTGCAGCTTCCCAACTGCTGGCAGTTTCTTGTTGTTTTTTTCGGCCTGTCACGGCTGGGAGTCGCTCCGGTTCTGGCCCT
GCCTGCGCACAGGCTATCAGAAATTTCCTCCTTCACAGGGGTAACTGAGGCAAAAGCCTATATTTGCGCTGCCAGGTCGG
CCGGTTTTGATTACCGGCAGCTGGCGCGTGAACTGCAGGAAAGGCACCCGGGCCTGAAGCACGTAATCGTGAGCGGCGAG
CCGGAAGAATTCATTTCCCTTGAAGGTCTGTTGGCGTCATCGACCGATCTTCCGCAAGATCCTGTTTCGTCAGATTCACT
GCTCTGTTTTCTTCTTTCTGGCGGCACGACCAGCGTTCCCAAGCTGATTGCCCGCGTTCATTGCGAATATTCGTGCGTCA
CCCGTTACAGTGCCGCCGCCAACGGTTTTGATGAAACCACGGTATATCTGGCTGCACTGCCAATGGCACACAACTTTCCG
CTCGGCGCTCCCGGTGTGCTGGGAACGCTTCAATGCGGCGGTACCGTGGTCATCGCCGAAACCCCTGAACCGGATATGTG
CTTTGACCTTATTGACAGGAACATGGTTACCCATACCGCTCTTGTGCCGCCCGCAGCTATACTCTGGTGCGACATGGCCG
AATTGTTGGAGCGCCAGAATACCTTTCCAAGTTTGAGCAACATCCAGGTTGGTGGTTCACGGGTTGGCGAAGACCTTGCC
CAACGCACTACAGAAATCTTTGGCTGCCGCTTTCAGAATGTTTTTGGCATGTCAGAAGGTCTGATCAGTATGACCCGTAT
GGATATGGATGAGGAAATAGTCCGCAATACGCAGGGATTGCCCGTGTGCCCGGCTGACGAGTTTCGCATCGTTGATCCTG
CTGGCCGTGAAGTGCCTGATGGAGTCGTGGGTGGCCTGCAGATTCGTGGACCGTACACCATACATACTTACTTCAAACGG
CCCGAAGCCAATGCGGAATCATTCACCGGGGACGGATTCTTTTGTACCGGGGACCTTGCGCGGCGCAGGTCTGATGGTTG
CCTGGTGCTTGAAGGACGTGAAAAAGATCAGATCCAGCGGGGAGGCGAAAAGATCATTCCCGAAGAAGTGGAAAGTGTTC
TTGTCGCCCACAGGGAAGTCCGGGATGCGGTTCTTCTGGGCATTCCCGACAAGCTGCTTGGCGAAAAGATCTGCGCCTTC
ATCTTTGTGCATGAACACAGGGATGAAGAAGAGGTCAATGACCGCGCCCTCCGGCGCTTCCTCCAGAGTGAAGGGCTGAG
TACGTTCAAGATTCCTGATCAGTTTATTTTTGTTACGTCTTTTCCAAGTACGGCAGTGGGCAAAAATAACCGCCGCAAAC
TGAGGGAGCAGCTTCTTCAGCAATACTACCGGAGCGTCAGTGTTCCTGCAGGAGTGGAAAATGCCAGTTGA

Protein sequence : 
MLYARDLGWPQDIINKYRAEDYWRDETFNTLLQDVAGRKGDCMAVVDGNVRLTYAEFKEMVDRIAGGFAALGLGAGDHVV
VQLPNCWQFLVVFFGLSRLGVAPVLALPAHRLSEISSFTGVTEAKAYICAARSAGFDYRQLARELQERHPGLKHVIVSGE
PEEFISLEGLLASSTDLPQDPVSSDSLLCFLLSGGTTSVPKLIARVHCEYSCVTRYSAAANGFDETTVYLAALPMAHNFP
LGAPGVLGTLQCGGTVVIAETPEPDMCFDLIDRNMVTHTALVPPAAILWCDMAELLERQNTFPSLSNIQVGGSRVGEDLA
QRTTEIFGCRFQNVFGMSEGLISMTRMDMDEEIVRNTQGLPVCPADEFRIVDPAGREVPDGVVGGLQIRGPYTIHTYFKR
PEANAESFTGDGFFCTGDLARRRSDGCLVLEGREKDQIQRGGEKIIPEEVESVLVAHREVRDAVLLGIPDKLLGEKICAF
IFVHEHRDEEEVNDRALRRFLQSEGLSTFKIPDQFIFVTSFPSTAVGKNNRRKLREQLLQQYYRSVSVPAGVENAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-92 44
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-92 44
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-92 44
ybtE CAA21394.1 - Virulence HPI Protein 2e-92 44
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-92 44
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-92 44
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-92 44
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-92 44
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-92 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ddes_1338 YP_002479918.1 AMP-dependent synthetase and ligase VFG0168 Protein 3e-108 47
Ddes_1338 YP_002479918.1 AMP-dependent synthetase and ligase VFG1817 Protein 9e-88 42