Gene Information

Name : Achl_4512 (Achl_4512)
Accession : YP_002478439.1
Strain :
Genome accession: NC_011881
Putative virulence/resistance : Resistance
Product : alkylmercury lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.99.1.2
Position : 21899 - 22564 bp
Length : 666 bp
Strand : +
Note : cleaves the carbon-mercury bond of organomercuric compounds

DNA sequence : 
ATGACGAACGACATTAGCCACGTTACTGAACGCCTCGCCACCGGGGAGACCGGCATGCAGCCCTGGCTGTGGTTGCCGCT
GATGAAGCTCCTCGCCCTGGGTGACCCGGTCGACATCGCGGACCTTGCCGCCGCGACCGGGCGGCCCGTCGAGGAAATCC
GCGCGGCGCTTGAGGCCATGGCCGACACCGAATACGACGGTTCAGGCCGGATCGTCGGGCAGGGCCTGACTCAGCGTCCC
ACGCAGCACCGCTTCGAAGTCGGCGGCGAACAGCTCTACACCTGGTGCGCACTCGACACCCTGATTTTCCCGACCCTCCT
CGGCGCCCCCGCCCGGATCGAGTCCGCCTACAAATCAACCGGAACACCGGTTCGGGTGCGCGTTGACAGCTCCGGTGTCA
CCAGCGTCGAACCGGCTACAGCCGTGGTCTCCCTGGTCAACCCGGAGGACATGAGCTCGGTCCGGTCCTCCTTCTGCAAC
CAGGTCCACTTCTTCGCCTCACCCGATGAGGCAGGACCATGGCTCGAAAACCACCCCGAAGGGACGGTCATCCCCGTCGA
GGAGGCATACCGGCTCGCGTCCACCATGGCCGACCAAATGCTCGCCGGGACCACCAGCCAGAACAGGGAAAAACCGGGCA
ACGGAGCGCAAAGCTGCAGCTGCTGA

Protein sequence : 
MTNDISHVTERLATGETGMQPWLWLPLMKLLALGDPVDIADLAAATGRPVEEIRAALEAMADTEYDGSGRIVGQGLTQRP
TQHRFEVGGEQLYTWCALDTLIFPTLLGAPARIESAYKSTGTPVRVRVDSSGVTSVEPATAVVSLVNPEDMSSVRSSFCN
QVHFFASPDEAGPWLENHPEGTVIPVEEAYRLASTMADQMLAGTTSQNREKPGNGAQSCSC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merB BAB47641.1 organomercurial lyase Not tested Type-III SCCmec Protein 1e-46 55
SE0086 NP_763641.1 alkylmercury lyase Not tested SCCpbp4 Protein 1e-46 55

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Achl_4512 YP_002478439.1 alkylmercury lyase BAC0658 Protein 7e-47 55
Achl_4512 YP_002478439.1 alkylmercury lyase BAC0663 Protein 4e-48 54
Achl_4512 YP_002478439.1 alkylmercury lyase BAC0654 Protein 3e-48 54
Achl_4512 YP_002478439.1 alkylmercury lyase BAC0657 Protein 2e-35 46
Achl_4512 YP_002478439.1 alkylmercury lyase BAC0659 Protein 1e-33 44