Gene Information

Name : Achl_4511 (Achl_4511)
Accession : YP_002478438.1
Strain :
Genome accession: NC_011881
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 20410 - 21858 bp
Length : 1449 bp
Strand : +
Note : TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: aau:AAur_pTC10241 mercuric reductase

DNA sequence : 
ATGACTGAAGCAGCAGCAGCGTTTGATTATGATCTGGCAGTGATCGGCTCAGGCGGCGGTGCGTTCGCCGCCGCGATCAG
AGCCACCAACCTGGGCAAGCGGGTGCTGATGGTGGAGCGGTCCACCGTCGGCGGGACTTGCGTGAATACCGGTTGTGTTC
CCTCCAAGGCGCTGTTGGCAGCGGCGGAGGCGCGGCATGTGGCACTGGATGCCTCCGGCCGGTTCCCCGGGATCAGCACT
ACATCCGAACCGGTCGATATGGCCGCGCTCATCGAGGGAAAACGTTCCCTGGTGGAGACGATGCGAGCCGACAAGTACGT
GGACCTGGCCGCCGAGTACGGGTGGGAGTTGCGCCAGGGCAACGCCGCGTTCGCCGGCAGTCCGCAGGAACCGGTTTTGG
AAGTCACTGGAGCGGATGGTGCCCGCAGTGAAGTGCGCGCCGAGCACTATCTGGTTGCGACCGGCTCGACCCCCTGGGCG
CCTCCGATCGAGGGCCTTCAGGATGTCGAGTATCTGACCTCGACCACGGCCATGGAACTGGACGAGGTACCGGAATCACT
GCTGGTGTTCGGCGGCGGATACGTGGCGCTGGAACAGGCCCAGCTTTTCGCCCGCCTCGGGTCCAAGGTCACCATGCTGG
TCCGTTCCCGCCTGGCCTCGGCCGAGGAACCGGAAGCGTCCCGGGCCCTGATGAGCGTTTTCGCCGACGAGGGTATACGC
GTCGTCCGCCGTGCCACGGTTTCCGCGGTGCACACCGACCCAGCCACCGGGGAAGTCGTCGCAACCGCGACGGTCTCCGG
CGGGCAGGAACAATTCCGGGCCACCCGGCTCCTCGTGGCCATGGGCCGGCGCCCGGTCACCGAGGGTCTTAACCTGGACA
TCGTGGGCGTGAAGACCGGGGATCGCGGCGAAGTCCTAGTCCAGGACACGCTGGCGAGCACCAACCCCAGGATCTGGGCC
GCCGGGGACGTGACAGGGCACCGGGAATTCGTCTATGTCGCAGCCTCGCACGGCACCCTGATGGTGGAGAACGCATTCAA
CCAGGTCGGCCGCGAGGTCGACTACCGGCACCTGCCCCGGGTCACCTTCACCAGCCCAGCCCTGGCCGCTGTCGGCATGA
CCGACAAGGAAGCCAACGAGGCGGGCATCCGCTGCGAATGCCGGGTCCTGCCGCTGGAATACGTGCCCCGTGCCCTCGTA
AACCGTGACACCCGCGGGTTCATCAAGATCGTCGCCGACAACAGCACCGGCCGGATCGTGGGCATCACGGCCGTGGGTAA
GGAAGCCGGTGACCTGGCCGCGGCCGGCGTGTACATCCTGGAGGCCGGGATGACCGTGGATCAGGTCGCGAACCTCTGGT
CCCCGTACCTGACGATGGCCGAAGGTATCAAAATCGCCGCCCAGTCCTTCAAAACGGACGTCTCCAAACTCTCCTGCTGC
GCCTCCTGA

Protein sequence : 
MTEAAAAFDYDLAVIGSGGGAFAAAIRATNLGKRVLMVERSTVGGTCVNTGCVPSKALLAAAEARHVALDASGRFPGIST
TSEPVDMAALIEGKRSLVETMRADKYVDLAAEYGWELRQGNAAFAGSPQEPVLEVTGADGARSEVRAEHYLVATGSTPWA
PPIEGLQDVEYLTSTTAMELDEVPESLLVFGGGYVALEQAQLFARLGSKVTMLVRSRLASAEEPEASRALMSVFADEGIR
VVRRATVSAVHTDPATGEVVATATVSGGQEQFRATRLLVAMGRRPVTEGLNLDIVGVKTGDRGEVLVQDTLASTNPRIWA
AGDVTGHREFVYVAASHGTLMVENAFNQVGREVDYRHLPRVTFTSPALAAVGMTDKEANEAGIRCECRVLPLEYVPRALV
NRDTRGFIKIVADNSTGRIVGITAVGKEAGDLAAAGVYILEAGMTVDQVANLWSPYLTMAEGIKIAAQSFKTDVSKLSCC
AS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 1e-87 45
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 1e-87 45
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 3e-68 43
merA ABQ57371.1 MerA Not tested SGI1 Protein 5e-70 42
merA AGK07021.1 MerA Not tested SGI1 Protein 5e-70 42
merA AGK07079.1 MerA Not tested SGI1 Protein 5e-70 42
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 3e-68 42
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 4e-68 42
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-65 41
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-67 41
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 3e-67 41
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-67 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Achl_4511 YP_002478438.1 mercuric reductase BAC0651 Protein 6e-88 45
Achl_4511 YP_002478438.1 mercuric reductase BAC0224 Protein 3e-86 45
Achl_4511 YP_002478438.1 mercuric reductase BAC0652 Protein 2e-70 42