Gene Information

Name : kdsB (HAPS_0972)
Accession : YP_002475545.1
Strain : Haemophilus parasuis SH0165
Genome accession: NC_011852
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 957905 - 958672 bp
Length : 768 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAGTTTTACCGTCATTATCCCCGCTCGTTATTCCTCTACACGTTTACCGCATAAGCCCCTGTTAGATATTGCAGGTAA
ACCGATGATCCAACACGTTTGGGAAAAGGCACAACAATCTGGAGCCACTCGTGTAATCGTCGCGACCGATCACCCCGAAA
TCGAACAGGTTGTTACAAGGTTTGGAGGAGAAGTGTGCTTGACGTCAGATAAACATAATTCTGGCACAGAACGTTTAGCC
GAAGTGATTGAAAAAATGGCGATTGCAGATGATGAAATTATCGTGAATATTCAAGGCGATGAACCACTTATTCCGCCTTT
GATTGTGGCACAAGTGGCTGAAAATTTAGATAAACATCAAGTCAATATGGCAACCCTTGCGGTTAAATTGACAACACGAG
AAGAGCTATTTAATCCCAATGTGGTTAAAACATTAACGGATAAAAACGGAATGGCACTCTATTTCTCTCGTGCAACAATC
CCTTTTGGACGTGATTATTTCCCTCAATGTGACGATGCTTTTGTTCAACAACAAAACTACCTTCGTCATATCGGAATCTA
TGCTTACCGTGCAGGTTTTGTTAAGCAATATGTGGCTTGGGAGCCAACGGCATTAGAACAGCTAGAGTCGCTAGAGCAAC
TTAGAGCATTATGGTATGGCGAGAAAATTCATCTCGACTTAGCGAAAGAAGCCCCTCAAGTTGGGGTGGATACGGCGGAG
GATTTGGAGCGGGTGAGACAGATTTTAAATATCCTATGCTCGCAATAA

Protein sequence : 
MSFTVIIPARYSSTRLPHKPLLDIAGKPMIQHVWEKAQQSGATRVIVATDHPEIEQVVTRFGGEVCLTSDKHNSGTERLA
EVIEKMAIADDEIIVNIQGDEPLIPPLIVAQVAENLDKHQVNMATLAVKLTTREELFNPNVVKTLTDKNGMALYFSRATI
PFGRDYFPQCDDAFVQQQNYLRHIGIYAYRAGFVKQYVAWEPTALEQLESLEQLRALWYGEKIHLDLAKEAPQVGVDTAE
DLERVRQILNILCSQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-39 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 7e-39 42
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-38 42