Gene Information

Name : leuS (HAPS_0952)
Accession : YP_002475527.1
Strain : Haemophilus parasuis SH0165
Genome accession: NC_011852
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 932243 - 934831 bp
Length : 2589 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGATGCAACAACAATACAATCCGAGTGCGATTGAGCCTAAAGTACAGCAGTACTGGGCTGAAAATAAAGTATTCAAAGC
AATTAAAGACGAAAGCAAACCAAAATATTACTGTTTATCTATGTTCCCATACCCGTCAGGTCGTCTGCATATGGGACACG
TTCGTAACTATACGATCGGCGATGTGGTTTCCCGTTATCAACGTATGAACGGCAAAAATGTGTTACAACCAATGGGTTGG
GACGCATTCGGCTTGCCTGCAGAAGGGGCAGCGGTAAAAAATAAAACTGCACCAGCAAAATGGACTTATGAAAATATTGA
ATATATGAAAAATCAGCTCAAGGCCTTAGGTTTTGGCTTTGACTGGGATCGTGAAGTGACCACTTGCCGTCCTGAATATT
ATAAATGGGAGCAATGGTTCTTCACTGAATTGTACAAAAAAGGCTTAGTATATAAGAAAACATCGACAGTAAACTGGTGT
CCGAATGATGAAACGGTGTTAGCAAATGAGCAAGTCCACGAAGGCTGTTGCTGGCGTTGTGATACCCCTGTGGAACAAAA
AGAAATTCCGCAATGGTTTATTAAAATTACTGACTATGCGGAGCAATTGTTAAATGACTTAGATCGTCTTCCGTTATGGC
CAGATCAAGTGAAAACAATGCAACGCAACTGGATCGGTCGTTCTGAAGGGGTTGAAATTACTTTTAAAGTGAAAGGCACT
GATCAAACCTTGCCTGTTTATACTACTCGTCCAGATACTTTCTTTGGTGTGAGCTATGTGGCAGTGGCGGCGGCTCACCC
ATTAGCAACCCTGGCAGCAGAAAACAATCCTGCATTAGCTGCCTTTATTCAAGAAGCGAAAAACACCAAAGTGGCGGAAG
CGGATATTGCCACAATGGAGAAAAAAGGAATGGCAACAGGGTTGTTTGCTATTCACCCCTTAACAGGCGAAGAAGTTCCT
GTCTGGGTCGCTAACTTTGTGTTGATGCACTACGGCACTGGGGCTGTAATGGCAGTACCTGCTCACGATGAGCGTGATTT
TGAATTTGCACAAAAATACAATTTACCAATTAAACAGGTGATCGTACCGCTTGATGGTTCTGAATGGGATTTCAGCAAAG
CGGCAATGACTGAACACGGTAAATTGATTAACTCTGCGGAATTTGATGGGTTAGATTTTGATGGCGCTTTCAAAGGCATT
GCGGATAAATTAGAAGGAATGGGGATCGGTAAACGTCAAGTTAATTACCGCTTGCGTGACTGGGGCGTTTCTCGCCAACG
TTACTGGGGGGCGCCAATTCCAATGCTTACCCTTGAAAATGGCGAAACTGTGACTGTACCAATGCAAGATTTACCTGTGG
TGTTACCTGAAGATGTGGTGATGGACGGCGTGAAAAGCCCGATCAAAGCAGATCCAGAATGGGCGAAAACCACTTATAAC
GGTCAGCCAGCGTTAAGAGAGACAGATACTTTCGATACCTTTATGGAGTCTTCTTGGTATTATGCACGTTATGCGTCGCC
ACAATATCAACAAGGTATGTTAGACAAAGAAGAAGCAAACTACTGGCTACCTGTGGATCAATATATCGGCGGTATCGAAC
ACGCAACAATGCACTTGCTCTACTTCCGCTTCTTCCACAAATTATTGCGTGATGCCGGTTTCGTGACTAGCGATGAACCG
ACAGAAAAATTACTCTGTCAAGGTATGGTGTTAGCGGACGCTTATTACTACACCAGCCCAACCAATGAACGTATTTGGGT
GTCGCCAACAGAAGTGACAGTTGAACGTGATGAAAAAGGGCGTATTTTGAAAGCCTTTGACAAAGAAGGGCGTGCGTTGG
TACACAGCGGTATGACCAAAATGTCGAAATCGAAAAACAACGGTATTGATCCACAAGAAATGGTGGAAAAATATGGTGCG
GATACGGTGCGTCTATTTATGATGTTTGCTTCCCCTGCGGAAATGACATTAGAATGGCAAGAGTCTGGCGTAGAAGGGGC
GAAACGTTTCTTAGGTCGTCTTTGGAACTTGGCTTATGAGTATGCACAATCGCCAGCCACTGTTGCATTAGATCCTACGG
CATTAAGCAAAGAGCAAAAAGATTTACGCCGTGACGTACATAAAACCATTGCGAAAGTGAGTGATGACATCGGTCGCCGT
CAAACCTTTAATACCGCAATTGCAGCAATTATGGAATTGATGAATAAGCTCACCAAAGCACCGCTTGTTAATGATCAAGA
CAAAGCCGTGATGGCTGAAGCATTAAATGCGGTGATCCGTATGCTCTACCCAATCACCCCGCATATCTGCTTTGAACTAT
GGCAAGCCTTAGGCAATGAGGGTTCAATTGACTTTGCACCTTGGGTGGTGGCAGATGAAAAAGCAATGGTAGAAGATGAA
AAACTCGTTGTAGTGCAAGTAAATGGTAAAGTGCGTGGCAAAATTACTGTATCTGCAACCGCAACGGAAGATGAAGTCAA
GGCGATTGCGAAAGCCGATGAAAATGTGGCGAAATATCTTGAAGGCGTAGAAATCGTGAAAGAGATCTATGTACCGTTTA
AGATGTTGAGTTTTGCGGTGAAAGCATAA

Protein sequence :
MMQQQYNPSAIEPKVQQYWAENKVFKAIKDESKPKYYCLSMFPYPSGRLHMGHVRNYTIGDVVSRYQRMNGKNVLQPMGW
DAFGLPAEGAAVKNKTAPAKWTYENIEYMKNQLKALGFGFDWDREVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWC
PNDETVLANEQVHEGCCWRCDTPVEQKEIPQWFIKITDYAEQLLNDLDRLPLWPDQVKTMQRNWIGRSEGVEITFKVKGT
DQTLPVYTTRPDTFFGVSYVAVAAAHPLATLAAENNPALAAFIQEAKNTKVAEADIATMEKKGMATGLFAIHPLTGEEVP
VWVANFVLMHYGTGAVMAVPAHDERDFEFAQKYNLPIKQVIVPLDGSEWDFSKAAMTEHGKLINSAEFDGLDFDGAFKGI
ADKLEGMGIGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGETVTVPMQDLPVVLPEDVVMDGVKSPIKADPEWAKTTYN
GQPALRETDTFDTFMESSWYYARYASPQYQQGMLDKEEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGFVTSDEP
TEKLLCQGMVLADAYYYTSPTNERIWVSPTEVTVERDEKGRILKAFDKEGRALVHSGMTKMSKSKNNGIDPQEMVEKYGA
DTVRLFMMFASPAEMTLEWQESGVEGAKRFLGRLWNLAYEYAQSPATVALDPTALSKEQKDLRRDVHKTIAKVSDDIGRR
QTFNTAIAAIMELMNKLTKAPLVNDQDKAVMAEALNAVIRMLYPITPHICFELWQALGNEGSIDFAPWVVADEKAMVEDE
KLVVVQVNGKVRGKITVSATATEDEVKAIAKADENVAKYLEGVEIVKEIYVPFKMLSFAVKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-158 43