Gene Information

Name : smpB (HAPS_0661)
Accession : YP_002475257.1
Strain : Haemophilus parasuis SH0165
Genome accession: NC_011852
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 673049 - 673525 bp
Length : 477 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAGTAAAAAACCAAAAGTAGCTTCAAACACGATTGCCTTAAATAAACGTGCCAGACACGAATATTTTATCGAAGAAGA
AATCGAAGCTGGTCTAGAATTACAAGGCTGGGAAGTCAAATCCCTGCGAGCAGGCAAAGCCAATATCGGCGATAGCTATG
TCACTTTCCGTAATGGCGAAGCCTTTTTATTCGGTGGCACTATTACCCCGTTAAATGTCGCTTCTACCCATATTGTGTGC
GACCCAACCCGTACCCGTAAATTATTGTTAAATAAGCGTGAGTTAGACACGCTTTATGGTAAAGTCAGCCGTGATGGGTT
TACCGTTGTCGCCCTGTCGCTCTACTGGAAAAATGCGTGGGCGAAGGTCAAAATCGGCTTGGCGAAAGGGAAAAAATTGC
ACGATAAACGTGAAGATATTAAAGACCGTGAGTGGCAAGTTGCTAAACAGCGGATTATGAAGAATGCGAATAGGTAG

Protein sequence :
MSKKPKVASNTIALNKRARHEYFIEEEIEAGLELQGWEVKSLRAGKANIGDSYVTFRNGEAFLFGGTITPLNVASTHIVC
DPTRTRKLLLNKRELDTLYGKVSRDGFTVVALSLYWKNAWAKVKIGLAKGKKLHDKREDIKDREWQVAKQRIMKNANR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 5e-51 67
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 4e-23 46
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 4e-19 43