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Name : hsdR (HAPS_0350) Accession : YP_002474982.1 Strain : Haemophilus parasuis SH0165 Genome accession: NC_011852 Putative virulence/resistance : Unknown Product : Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : - Position : 379862 - 383026 bp Length : 3165 bp Strand : + Note : COG:V;COG0610 DNA sequence : ATGCTCATCAACGAAAACACCATTGAACAAGCCTGTTTGCGATTTTTGCAGGAATTGGGTTGGGATTATACGCACGGTTC GACCATCAATGCCGATGGGGAAAATCCTTGGCGGTTGCGGACGGACGAGGTGGTGTTTCGGGCGGTGTTGCGTGAGGCGG TGGAGCGGTTAAATCCGCAGTTGCCGTCTGCTACGGTGGACGAAGTGGTGGCGTTGGTGTGCAAAACGGATATTACAGAT TTAACGGAGCGTAATCAGCAAGCCTATCGCTACTTGCGTGAGGGCGTTCGGGTGGAATATCGGGAAAATGATGAGCAAAA GGTGGAGTTTGCCCGTTTAATTGATTTTCAACAGCCAAGCCTGAACCGTTTTGATGTGGTGAACCAGCTGACGATTTTGG GGCGGAAGGGCAATCGCCGTCCTGATGTGATTTGTTATATCAATGGCTTGCCTGTGGTGGTGTTGGAGTTGAAAAATCCT TTGAAAGAGAATGCGGATTTGCCACAGGCGTTTAATCAGTTGCAGACGTATAAGCAGGAAATCGGCGATCTGTTTGTGTA TAACCAAGCCCTTGTGATTAGCGATGGCATTTTGGCAAAAGTCGGTTCGCTGACGGCGGATTTGGAGCGGTTTACCCCTT GGCGTGTGGTGGACGAGAAGAACAAGCAACGTATTTCGTTTGAACACGAGTTGGAAGGCTTGGTGCGTGGTTTGCTTAAC CCTGCGAGTTTGTTGGATTATATCCAGAATTTTATTGTGTTTGAGCAAACCTCAAGCGGTCGTTTGGTGAAGAAAATTGC GGCTTATCATCAATTCTACGGCGTGAATGAAGCGGTGGATTGTACGCTGTGGGCGGCGAGCGATCAGGGCAATGGCAAAA TCGGGGTGATGTGGCATACACAAGGTTCGGGCAAGTCGTTGTCGATGTTGTTTTATGCGGGCAAATTGTTGTCGCAAGCG GAATTACGCAACCCGACTATTGTGGTGGTTACCGACCGCAATGATTTAGACGGTCAGCTTTATGCCACTTTTTCAGGCGG TCAGGCGTTAATTCGTCAGCAACCTGTGCAAGCAGACGGCAGGGAGGCGTTGCGTGAAGAACTTGCCAAGCGAGAAACAG GCGGTGTGATTTTTACCACCATTCAGAAATTCGGTTTACAAGAGGGCGAGCAGGCACACCCTGTGCTAAACGAGCGACAC AATATTATTGTGATTAGTGATGAAGCACACCGTTCGCAATATGGGTTTAGCCAAAGTATGAAGCTCAACGAAGCAAACCG CACGGGGACATATCGGGTGGGCTATGCGAAGCATTTGCGTGATGCCTTGCCGAATGCCTCTTTTATTGGTTTTACTGGTA CGCCGATTAGCCTTGAAGATAAAGATACGCAGGAAGTGTTCGGTAAATATGTGTCGATTTACGATATTACCGATGCGGTG GAAGATGGGGCGACTGTGCCGATTATCTATGAAGCACGGCAAATTCCCATTGCACAGAGTGCCGAGTTTGAGAATGTGGT GCGTGAAGCCCAAACCTTGCTTGATGAAGATGATGAAAGTAGCTACAACTTCCGTTTGCGTGAAAAATTGATGGGAACAG ACGGGCGTTTGAGCCGTTTAGCCGAAGATTTTGTAAAACATTTTGAACAACGCACCGCTTTAATTGACGGCAAGGCAATG GTGGTGGCGATGAGCCGTCAGATTTGTGTGAAATTGTATGAAAAAATCACCGCACTTCGTCCAGAGTGGCATAGCGATGA TGTGAATGAAGGGGCGATTAAAATTGTGATGACGGGCTCGGCGAGCGATCCTGAGGAAATTCAAAAACACATTTATTCTT CGCAAGATAAAAAGCTGTTGGAACGCCGCTTTAAAGATCCGGACGATCCGCTAAAAGTGGTGATTGTGCGTGATATGTGG CTAACAGGTTTTGATGCCCCTTGTTGCAATACGATGTATATTGATAAGCCGATGAAAGGGCATAATTTAATGCAGGCGAT TGCAAGGGTAAACCGTGTGTTTCGCAATAAAAGCCGTGATAATGGCGGTTTGATTGTGGATTATGTGGGGCTAACCAGCG AACTTCGGGAAGCCACCGAGCAATACACTCGCTCGCACGGCAAAGGGCAGATGACCCACAATATCGCCGAAATTAAGGTG AAGATGTTGGAATACATTGATGTTGTGCGTGGGCAGTTTGCCACACCGGTGAATGGTCAGTCGTTTAAGCTGTTTGATGC CTTGAAAATCGAAGATGAACTGGCGTTGTTCCAGCAAGTGATGTTGGGGGCGAACTATATTTTAGCCTTAGATCATCAAA TGGTTGCGGATAAAACGGAGAAAACCCCAAGACGCAATGCGTTTTTAAAAGCGGTGCGTTTGGCGAAAAAAGGGTTTAGC TTATGTGGTGCAGACGGCGATGTTCAGCAATATCAAAAAGAGCTTGCCTTTTATGATGCGGTGCGTGCGATTTTGGCAAA ACGTGAGCCAAATTCAACCGCTTCAAACGAAGAACGCCAGTTGCAGTTGGTGGCATTATTGAATAAGGCGGTGGACGCAA GCGGTGCGATTAACCTGTTTGATTTGCTTAACCGAGAACAGCCGAACATCAATATTTTGTCGGACGAATTTTTAGAGAAA ATCAAAAACAGCCAAACCAAAGAACTTTGGTTGTTGGCAGTGGAACGTTATTTGCGTAGCCAAATCAATGAGAAAGGGGC GGGCAATTTGGCGGTGCAAAAAGATTTTGCCGAGCGTTTGAAACAGGCGTTAAATCAATACCACAACCAAAATCTCACCA TTATGCAAGTGTTGGAAGAGTTGCTGAATATGAGCAAGGAATTTACCGAACGCTTGCAACGTGGGGAAAAATTGGGTTTA TCACCTGCGGAAATCGCCTTTTACGATGCCCTTGCTCGCAATGAAAGTGCGGTGCGAGAATTGGGCGATGATGCCTTGAA AAATTTGGCAAAAGCGATTACCGATAAATTACGCAAATCCGCCACCATTGACTGGCAATACAAAGAAGCCGTGCGAGCCA AAATGCGAAACTTGGTGCGTGTAACGTTGAGATTATTCAAATATCCACCGGATAAATGCGATGAGGCAATCCAATTTGTG TTGGAACAAGCGGAAGTGATTGCGGATGAATTGACGACGGTATAA Protein sequence : MLINENTIEQACLRFLQELGWDYTHGSTINADGENPWRLRTDEVVFRAVLREAVERLNPQLPSATVDEVVALVCKTDITD LTERNQQAYRYLREGVRVEYRENDEQKVEFARLIDFQQPSLNRFDVVNQLTILGRKGNRRPDVICYINGLPVVVLELKNP LKENADLPQAFNQLQTYKQEIGDLFVYNQALVISDGILAKVGSLTADLERFTPWRVVDEKNKQRISFEHELEGLVRGLLN PASLLDYIQNFIVFEQTSSGRLVKKIAAYHQFYGVNEAVDCTLWAASDQGNGKIGVMWHTQGSGKSLSMLFYAGKLLSQA ELRNPTIVVVTDRNDLDGQLYATFSGGQALIRQQPVQADGREALREELAKRETGGVIFTTIQKFGLQEGEQAHPVLNERH NIIVISDEAHRSQYGFSQSMKLNEANRTGTYRVGYAKHLRDALPNASFIGFTGTPISLEDKDTQEVFGKYVSIYDITDAV EDGATVPIIYEARQIPIAQSAEFENVVREAQTLLDEDDESSYNFRLREKLMGTDGRLSRLAEDFVKHFEQRTALIDGKAM VVAMSRQICVKLYEKITALRPEWHSDDVNEGAIKIVMTGSASDPEEIQKHIYSSQDKKLLERRFKDPDDPLKVVIVRDMW LTGFDAPCCNTMYIDKPMKGHNLMQAIARVNRVFRNKSRDNGGLIVDYVGLTSELREATEQYTRSHGKGQMTHNIAEIKV KMLEYIDVVRGQFATPVNGQSFKLFDALKIEDELALFQQVMLGANYILALDHQMVADKTEKTPRRNAFLKAVRLAKKGFS LCGADGDVQQYQKELAFYDAVRAILAKREPNSTASNEERQLQLVALLNKAVDASGAINLFDLLNREQPNINILSDEFLEK IKNSQTKELWLLAVERYLRSQINEKGAGNLAVQKDFAERLKQALNQYHNQNLTIMQVLEELLNMSKEFTERLQRGEKLGL SPAEIAFYDALARNESAVRELGDDALKNLAKAITDKLRKSATIDWQYKEAVRAKMRNLVRVTLRLFKYPPDKCDEAIQFV LEQAEVIADELTTV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 51 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 42 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 42 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 41 |
