Gene Information

Name : guaA (HAPS_0297)
Accession : YP_002474932.1
Strain : Haemophilus parasuis SH0165
Genome accession: NC_011852
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 328462 - 330033 bp
Length : 1572 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAAACATACACAACCACAAAATCTTAATCCTTGACTTTGGTTCACAATATACCCAACTGATCGCACGTCGTGTGCG
TGAAATCGGGGTTTACTGCGAACTTTGGGCTTGGGACGTGACGGAAGAACAGATCCGTGAATTTAACCCAACGGGTATTA
TTCTTTCTGGCGGTCCTGAAAGTACCACCGAAGAAAACAGCCCACGTGCGCCTGAATATGTGTTTAACGCCGGCGTGCCT
GTACTTGGCATTTGCTACGGTATGCAAACGATGGCGATGCAGTTAGGCGGTTTAACGGAAACTTCAGATCACCGTGAATT
TGGCTATGCATCTGTTGAATTGAAAGCAACCGATAGCTTATTTGCAAAATTAAACGATGATCTGACCGCTTGTAATCCAA
AACTTGACGTTTGGATGAGCCACGGCGATAAAGTCACCCGTTTACCGTCAAACTTCCAAATCACTGGCGTAACTCCAACT
TGCCCGATTGCGGCAATGTCGGACGAAAGTCGCCGTTTCTATGGCGTACAATTCCACCCAGAAGTAACCCATACGAAAAG
CGGTTTAGCTTTATTAACTAACTTCGTGGTAAACATCTGTGGTTGCGAAACCAAATGGACAGCGGAAAACATCATTGAAG
ATGCCGTAGCTCGCATTAAAGCCCAAGTTGGCGATGATGAAGTGATTTTAGGCTTATCAGGCGGTGTGGACTCTTCTGTT
ACCGCACTACTTTTACACCGTGCAATCGGCAAAAACTTGCACTGCGTATTCGTAGATAACGGCTTATTACGCTTAAACGA
AGGTGATCAAGTGATGGAGATGTTCGGCGATAAATTCGGCTTGAACATCATTCGTGTAAACGCTGAAGACCGTTTTTTAG
ATGCACTCAAAGGCATTGATGAACCTGAAGCGAAACGCAAAACTATCGGTAAAGTATTCGTTGATGTGTTCGATGATGAA
TCGAAAAAACTCACTTCAGTAAAATGGTTAGCACAAGGCACGATTTACCCAGATGTAATCGAATCCGCCGCCAGCAAAAC
AGGCAAAGCACACGTGATCAAATCGCATCACAACGTAGGCGGCTTGCCAGATTATATGAAACTCGGTTTAGTTGAACCAT
TGCGTGAATTGTTCAAAGATGAAGTACGTAAAATCGGCTTGGCATTAGGCTTACCAGCTGAAATGCTCAACCGCCATCCA
TTCCCCGGTCCAGGCTTAGGCGTGCGTGTGTTAGGCGAAATCAAAAAAGAATACTGCGATTTAGTCCGCCGAGCTGACGC
GATCTTTATGGAAGAACTACACGCCTCAGGCTGGTACTACAAAGTCAGCCAAGCCTTTACTGTATTCCTACCAGTCAAAT
CAGTAGGCGTAATGGGCGATGGACGTAAATATGATTGGGCTGTTTCCCTGCGTGCAGTCGAAACTATCGACTTTATGACT
GCACATTGGGCGCATTTACCTTATGATCTATTAGGTAAAATCTCAAATCGTATTATCAACGAAGTGAACGGGATTTCTCG
CGTGGTGTATGATGTTAGCGGAAAACCCCCAGCTACGATAGAGTGGGAATAA

Protein sequence :
MTNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFNPTGIILSGGPESTTEENSPRAPEYVFNAGVP
VLGICYGMQTMAMQLGGLTETSDHREFGYASVELKATDSLFAKLNDDLTACNPKLDVWMSHGDKVTRLPSNFQITGVTPT
CPIAAMSDESRRFYGVQFHPEVTHTKSGLALLTNFVVNICGCETKWTAENIIEDAVARIKAQVGDDEVILGLSGGVDSSV
TALLLHRAIGKNLHCVFVDNGLLRLNEGDQVMEMFGDKFGLNIIRVNAEDRFLDALKGIDEPEAKRKTIGKVFVDVFDDE
SKKLTSVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMLNRHP
FPGPGLGVRVLGEIKKEYCDLVRRADAIFMEELHASGWYYKVSQAFTVFLPVKSVGVMGDGRKYDWAVSLRAVETIDFMT
AHWAHLPYDLLGKISNRIINEVNGISRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-132 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-132 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-132 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-110 47