Gene Information

Name : tpx (HAPS_2084)
Accession : YP_002476488.1
Strain : Haemophilus parasuis SH0165
Genome accession: NC_011852
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 2045121 - 2045621 bp
Length : 501 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGACCCAAATTACATTAGCAGGCAACCCAATTGAAGTTGCAGGACAATTTCCACAAGCGGACAGTTTCGTGGCAGATTT
TACATTAGTGAGCAATGGCTTAGAAAACGTATCACTTTCCGACTTCGCAGGAAAACGCAAAGTTCTTAACATCTTCCCAA
GTATTGATACAGGTATTTGTGCAACTTCCGTGCGTGTTTTCAATAAAGAAGCCGCCGAACTCGCAAACACAGTGGTACTT
TGCATTTCTGCTGATCTTCCTTTCGCCCAAGCACGTTTCTGTGGTGCTGAGGGAATTGCAAATGCCCAAACACTTTCAAC
ATTCCGCAACAAAGCCTTCCATCAAGCGGTAGGCGTAGATATTGCAACAGGCCCATTAGCAGGTTTAACTGCTCGTGCAG
TGATTGTATTAGATGAAAACAATAAAGTGCTACACAGTGAATTAGTCCCTGAAATCAAACAAGAGCCTGACTATGCAGCG
GCGTTGGCAGTGTTGAAATAA

Protein sequence : 
MTQITLAGNPIEVAGQFPQADSFVADFTLVSNGLENVSLSDFAGKRKVLNIFPSIDTGICATSVRVFNKEAAELANTVVL
CISADLPFAQARFCGAEGIANAQTLSTFRNKAFHQAVGVDIATGPLAGLTARAVIVLDENNKVLHSELVPEIKQEPDYAA
ALAVLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 3e-33 47
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 2e-33 47
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 3e-33 46
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 2e-33 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_002476488.1 thiol peroxidase VFG0087 Protein 8e-34 47