Gene Information

Name : murD (HAPS_0117)
Accession : YP_002474764.1
Strain : Haemophilus parasuis SH0165
Genome accession: NC_011852
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : -
Position : 127085 - 128383 bp
Length : 1299 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGCAAAATCAATATCAAGGCAAAACTATCACAATTATCGGCTTAGGCACAACAGGCTTATCTTGTGTCGAATTTTTTGC
GGACAAACAGGCTCAAGTGCGAGTGATTGATACCCGAGCAAATCCTGCAGGGGCGGATAAGTTGTCGAAGGATATTCCAC
TACACACAGGCAGTTTAAACCTTGAGTGGCTATTAAGCTCCGACTTAATTGTGATTAGCCCGGGACTTGCTTTAGCAACT
GCTGAAATTCAGCAAGCTATTCAAGCCGGTGTGGAGGTGGTTGGCGATATTGAGTTGTTCTATCGTGAAGCCAAAGCGCC
GATTATTGCGATTACAGGCTCGAACGGTAAAAGTACCGTCACGACTTTGACGACTGAAATGGCAAAACAAGCCGGAGTTA
AAGTTGGAATGGGTGGCAATATCGGCGTGCCGGCATTGAGTTTATTGAAAGGCGATTACGAGCTTTATGTGTTGGAATTA
TCGAGTTTTCAACTTGAAACGACCTATTCTTTAAAAGCAAAAGCGGCGACCATTTTAAATATCAGCGAAGATCATATGGA
TCGCTATGAGAGCATTGAAGATTATCGCCAAGCGAAATTGAAAATTTATCACCATGCCGAAAATGTAATTGTGAATGGCG
AAGATCCGCAAACTTTCCCTGAACAAGCGGTCGGATCTTTGAAAAAATTTGCAGAAAAAGACGCAGAATATACCGCTTGT
AATGGAGAACTCTATTCTGGCGATGAAGCCGTCATTGCGATTGATGAGCTGAAAATTACTGGTCGCCACAATGTGATGAA
TGCCTTAGCATCAATGTCATTGGCGGAAGCTGCAGGCGTTGATCGTTCGGGTATTGTGAAAGCACTACAAAGCTATTCAG
GATTAGATCACCGTTTCCAGCTAGTACCGACGAATGATGGCGTACGCTGGATTAACGACTCAAAAGCCACGAATGTCGGC
AGTACTGTGGCGGCATTAAATGGTTTGCAAGTCGAAGGAACGCTTTATCTGTTGTTGGGCGGTGACGGAAAAGATGCTGA
TTTTTCTGAGTTAAAACCTTTTATTAATCAACCAAATACAGTCTGTTACTGCTTCGGAAAAGATGGGGCGGAACTCGCCG
CTTTAACTCAAAATAGCGTTTTAGTGGAAACAATGGAACAAGCTGTCGCACAAATTCGTTTAAGATTAAAAGCGGGCGAT
ATGGTGCTACTTTCACCAGCTTGTGCAAGTTTAGATCAGTTTAAAAATTTTGAAGAGCGTGGCAGACAGTTTGTGGCGTT
GGCTCAAGGGGTTATCTAA

Protein sequence :
MQNQYQGKTITIIGLGTTGLSCVEFFADKQAQVRVIDTRANPAGADKLSKDIPLHTGSLNLEWLLSSDLIVISPGLALAT
AEIQQAIQAGVEVVGDIELFYREAKAPIIAITGSNGKSTVTTLTTEMAKQAGVKVGMGGNIGVPALSLLKGDYELYVLEL
SSFQLETTYSLKAKAATILNISEDHMDRYESIEDYRQAKLKIYHHAENVIVNGEDPQTFPEQAVGSLKKFAEKDAEYTAC
NGELYSGDEAVIAIDELKITGRHNVMNALASMSLAEAAGVDRSGIVKALQSYSGLDHRFQLVPTNDGVRWINDSKATNVG
STVAALNGLQVEGTLYLLLGGDGKDADFSELKPFINQPNTVCYCFGKDGAELAALTQNSVLVETMEQAVAQIRLRLKAGD
MVLLSPACASLDQFKNFEERGRQFVALAQGVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 8e-65 43
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 8e-65 43