Gene Information

Name : leuS (CKR_3183)
Accession : YP_002473648.1
Strain : Clostridium kluyveri NBRC 12016
Genome accession: NC_011837
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 3586890 - 3589325 bp
Length : 2436 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGTACAGTACTAAAACAGATAAAAAATGGCAACAAAAATGGGATCAAACAAATATTTATACATTTGACGAAAAAAAATC
AAGCAAAAAATTATATACTCTAGAGATGTTCTCTTATCCTTCCGGCAGTAATTTACATGCAGGTCACTGGTTTAACTATG
CACCTGTAGATTCTTGGGCCAGAATGAAAAGAATGCAAGGATATAATGTATTCCAGCCCATGGGATTTGATGCTTTCGGT
CTTCCTGCTGAAAACTATGCCATAAAGACTGGAATTCATCCAAAAGATTCTACTGAAAAGAATATTGATACCATGGAAAA
ACAGCTTAAATCCATGGGAGCTATGTTCAATTGGGAGAATGAGGTAGTTACCTGCCGCCCTGATTACTATAAATGGAATC
AATGGCTATTTCTCCAATTATATAAACACGACTTGGCCTATAGGAAAAATGCCCCTGTAAATTGGTGTCCCAGCTGTAAT
ACAGTACTTGCCAATGAACAAGTAAAAGAAGGTGAATGTGAACGCTGTGGTACGGAAGTTACAAAAAAGGATCTAACACA
ATGGTTTTTTAAAATAACAGATTACACTGAAGAATTGCTTAAAGACCTTGATAATATAGATTGGCCGGAAAAGACAAAAG
CTATGCAAAGACACTGGATGGGTAAATCCACAGGTACAGATGTAACTTTTAAAGTAGCGGATTCTGATATAAAATTCAAT
GTATTTACCACTCGAGTGGATACATTGTTTGGTGTTACCTATGTAGTCATATCCCCTGAAAATGATTTAGTGGATAGTGT
CACTAAAGAAGAATATAAAGAAGAAATTGAAAAATATAGAGAAGCTGCTAAAAAGCAGACCGACATTGAAAGACAATCAA
TTACCAGAGAAAAAACAGGTGTATCTACGGGTTCCTACGCTATAAATCCTATAAACGGAAGAAAAGTACCTATATGGATA
GGAGATTATGTATTAAACACCTACGGTACAGGTGCTGTAATGGCAGTTCCTGCTCATGACGAAAGGGATTTTGAATTTGC
CACAAAATACAAATTACCTATTGAAAGAGTTATAGAAGGAGGTTCTTCCTTACCTTATGTAGAATACGGAAAGATGATAA
ATAGTGATAAATTCAATGGATTATATACTCCAGAAGGTAAAGAAGCTGTGACCAAGGAACTAGAAAACATTGGATTAGGT
TCTGGAAAAACAAATTATAGATTAAGAGACTGGCTTGTATCAAGACAAAGATACTGGGGAACACCTATACCTATAATATA
CTGTAAAAAATGCGGTACAGTCCCAGTACCAGAAAGTGATTTACCAGTTGAACTTCCTTATAATGTACAATTTTCTCCTG
ATGGAAAATCTCCCCTTCTAAAATCAGAAGAGTTTATGAATACTACGTGCCCTATTTGCGGTGAACCTGCCAAAAGAGAG
GCTGATACATTAGATACATTTGTGTGTTCCTCCTGGTATTACTTAAGATATGCCGATAATAAGAATACAGAAAAAGCCTT
TGACAAGGATAAGATAAATAAACTACTTCCTGTAGATATGTATGTAGGTGGTCCTGAACACGCATGTATGCACCTTTTGT
ATGCTAGATTTATCACTAAAGCACTTAGAGACATGGGTTTTTTAAATTTCGATGAACCTTTTCTATCTTTAAGACATCAA
GGACTGATACTTGGACCTGATGGTCAAAAAATGAGCAAGTCCAAAGGCAATACCATATCTCCAGATGACTGCATACAAAA
ATATGGTTCAGATGTATTTAGAATGTACTTAATGTTCGGATTTGACTATGCCGAGGGTGGTGCCTGGAACGATGACGGTA
TTAAATCCATGAGTAAATTTGTAGATAGAATTGAAAGAATTGTAGGAAATATAAAAGAACTTATAAATAGTGGTAAGAAC
TTTAAAAATTCAATGGATGCTGCAGAAAAAGAATTAAATTACTCAAGAAATTATTCAATAAAATCCGTATCAGAAGATGC
AGGAAAATTTCAATTCAACACAGCTATTGCTAGAATTATGGAATTTACAAATTCACTTTATAAATATATTCAGGAGGATA
CTAAAAATATATCCCTTTTAAAAGATACTATACTTGATTTTATAAAGATAATAGCTCCTTTTGCACCTCACTTTGCAGAG
GAACAATGGGAGGTATTAGGACAAAAATATTCTATATTTAATGAGAAATGGCCTGAATTTGACCCTAAGGCTTTAGTAAA
AGAAGAAGTAGAAATAGCCATTCAAATAAACGGTAAAATTAAGGCTAAAATAAATATACCTACAAATTTAAGTGATGAAC
AAATAAAAGAGTTATCCATATCCAATGATAATATTAAACCTTTATTAGAGGGAAAAAATATAAAGAAAGTTATAGTAGTA
AAAGGAAGACTTGTAAATATAGTAGTTAAACCTTAA

Protein sequence :
MYSTKTDKKWQQKWDQTNIYTFDEKKSSKKLYTLEMFSYPSGSNLHAGHWFNYAPVDSWARMKRMQGYNVFQPMGFDAFG
LPAENYAIKTGIHPKDSTEKNIDTMEKQLKSMGAMFNWENEVVTCRPDYYKWNQWLFLQLYKHDLAYRKNAPVNWCPSCN
TVLANEQVKEGECERCGTEVTKKDLTQWFFKITDYTEELLKDLDNIDWPEKTKAMQRHWMGKSTGTDVTFKVADSDIKFN
VFTTRVDTLFGVTYVVISPENDLVDSVTKEEYKEEIEKYREAAKKQTDIERQSITREKTGVSTGSYAINPINGRKVPIWI
GDYVLNTYGTGAVMAVPAHDERDFEFATKYKLPIERVIEGGSSLPYVEYGKMINSDKFNGLYTPEGKEAVTKELENIGLG
SGKTNYRLRDWLVSRQRYWGTPIPIIYCKKCGTVPVPESDLPVELPYNVQFSPDGKSPLLKSEEFMNTTCPICGEPAKRE
ADTLDTFVCSSWYYLRYADNKNTEKAFDKDKINKLLPVDMYVGGPEHACMHLLYARFITKALRDMGFLNFDEPFLSLRHQ
GLILGPDGQKMSKSKGNTISPDDCIQKYGSDVFRMYLMFGFDYAEGGAWNDDGIKSMSKFVDRIERIVGNIKELINSGKN
FKNSMDAAEKELNYSRNYSIKSVSEDAGKFQFNTAIARIMEFTNSLYKYIQEDTKNISLLKDTILDFIKIIAPFAPHFAE
EQWEVLGQKYSIFNEKWPEFDPKALVKEEVEIAIQINGKIKAKINIPTNLSDEQIKELSISNDNIKPLLEGKNIKKVIVV
KGRLVNIVVKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-161 44