Gene Information

Name : clpB (BLA_0676)
Accession : YP_002469545.1
Strain : Bifidobacterium animalis AD011
Genome accession: NC_011835
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 871976 - 874675 bp
Length : 2700 bp
Strand : -
Note : COG0542: ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGAGGATGATATGGAACAGAAATATACGACTTTGGCTCAGGAGGCCTTGGGCGACGCGGTGCAGAGCGCCTCGGCCGC
CGGCAACCCGCAGGTTGAGCCGCTGCATTTGCTTGACTCGCTGCTGCGTCAGGAGAACGGTGTCATCGGTGGTCTCATCG
AGGCCGTGGGGGCGAACAGGCAGACGATCGGCGCGCAGGTGCGCAATGCCCTGGTCTCGCTGCCGAGCGCTTCCGGCTCG
TCGACCGCGCAGGCTTCGGCCAGCCGCCAGCTGACCACCGCGTTGGCCGACGCCAGCAAGGAAATGAAGGACATGGGAGA
TGAGTACATCTCCACCGAGCACCTGCTGCTGGGCATTCTCGACGCCGCCCCGAACGAGGCGGCCAAGATTCTCGAGCAGA
ACGGCATCACGGCCGACAAGGTGCGCGCGGCCATCCCGAACGTGCGCGGTGGCGCCAAGGTGACGAGCCCGGACGCCGAG
GCCTCGTACAAGGCGTTGGAGAAGTTCTCCACCGACCTGACGGCCCGTGCCCGTGAAGGCAAGCTCGACCCGGTGATCGG
CAGGGATCAGGAGATCCGCCGTGTGATCCAGATTCTGAGCCGCCGCACGAAGAACAACCCGGTGCTGATCGGCGAGCCAG
GCGTGGGCAAGACCGCCGTCGTGGAAGGCCTCGCCGAGCGCATCGTGGCCGGCGACGTGCCGAGCACACTGCAGAACAAG
CGCCTCATCAGCCTCGACCTGGGCTCCATGGTGGCCGGGTCCAAGTACCGCGGCGAATTCGAGGAACGCCTCAAGGGCGT
GCTTGACGAGATCAAGCAGTCCGACGGCCAGATCATCACCTTCATCGACGAGATCCATACGATCGTCGGTGCCGGTGCGG
CCGAAGGCTCGATGGACGCGGGCAATATGCTCAAGCCTATGCTGGCCCGTGGCGAACTGCGCCTGATCGGCGCCACCACG
CTCGACGAATACCGTGAGAACATCGAGAAGGATCCGGCCCTGGAGCGTCGTTTCCAGCAGGTGTTCGTGGGCGAGCCGAG
TGTGGAGGACACGATCGCCATTCTGCGTGGCCTGAAGCAGCGCTATGAGGCCCACCACAAGGTGACGATCGGCGACGACG
CGCTCGTGGCCGCCGCAACCCTCTCGAACCGCTACATCACCGGTCGTCAGCTGCCCGACAAGGCCATCGACCTGGTGGAC
GAGGCCGCTGCGCACCTGCGCATGGAACTCGACTCGCAGCCCGAGGAGATCGACGAGCTGCAGCGCAAGGTGACGCGCCT
CGAAATGGAGGAGATGCAGCTGAAGAAGGCCGAGGACCCGGCCTCCAAGGAGCGCCTCGCCAAGCTCCAGAGCGAACTGG
CCGACGCCCGCGAGAAGCTCGCAGGACTCAACGCCCGTTGGAACGCCGAGAAGGAAGGCCACAACAAGGTCGGCGACCTG
CGTGCGCAGCTCGACGAGAAGCGCGTCGAGGCCGACAAGGCCACGCGTGAAGGCGACCTGGCGAAGGCGAGCCGCATTCT
GTACGGTGAGATCCCGGCCATTCAGAAGCAGCTGACCGAAGCCGAGCACGAGGCCGAGAAGGAAGCCGACTTCGCCCATG
AGGATGAGCCCATGGTCCCCGACCATGTGGACGCCGATTCGGTGGCCGGCATCGTCTCCGAATGGACCGGCATTCCGGTC
GGCCGTCTCATGCAGGGCGAGAACGAGAAACTGCTCAACATGGAGGAATACCTCAACAGGCGCGTGATCGGCCAGCCGGA
AGCCGTTCGTGCGGTCTCCGACGCCGTGCGCCGTTCGCGTGCAGGCCTGTCCGACCCGAATCGCCCGACCGGTTCGTTCC
TGTTCATGGGCCCGACCGGCGTGGGCAAGACCGAGCTCGCCAAGGCGCTCGCCGAATTCCTGTTCGACGACGAGAAGGCC
ATGATCCGCATCGACATGTCGGAGTACATGGAGAAGTCGTCGGTCTCGCGTCTCATCGGCGCAGCCCCGGGCTATGTCGG
TTACGAGGAGGGCGGCCAGCTCACCGAGGCCGTGCGTCGTCGTCCGTATTCGGTGGTGCTGTTCGACGAGGTGGAGAAGG
CCAATTCCGAGGTCTTCGACATTCTGCTGCAGGTGCTCGATGACGGCCGCCTGACCGATGGTCAGGGCCGCACCGTGGAC
TTCAAGAACACGATCCTGATCATGACGTCGAACCTCGGCTCGCAGTTCCTGGTCAACCCCGACCTGGATGAGCAGCAGAA
GAAGGACGCCGTGATGAACGCGGTGCACAGCCAGTTCCGTCCGGAGTTCCTCAACCGTCTCGACGACATGGTGATCTTCC
ACCCGCTCACACGCCAGGAGCTCGGCAAGATCGTCGACCTGCAGGTCAAGCAGGTGGCTTCGCGCCTCACCGACCGTCGC
ATCACGCTCGACGTCACCGAAGCGGCACGCGAATGGCTTGCCGACACCGGCTACGACCCGGCATACGGTGCGCGTCCGCT
GCGCCGTCTGGTGCAGACCGAGGTGGGCGACCAGCTGGCACGCATGCTGCTCGCCGGCGAGATCAAGGACGGTGACACCG
TGCTGGTGGACCACACCGGTGGCGAGCACCTCGAGCTCACCGACCATACGCACAACCCGATGGAAGGCGACCCGAACCCT
GGAGACTCCCAGATCACGGTTGACGACAAGAAGGATGACGGCGAACAGAAGGACGCCTGA

Protein sequence :
MEDDMEQKYTTLAQEALGDAVQSASAAGNPQVEPLHLLDSLLRQENGVIGGLIEAVGANRQTIGAQVRNALVSLPSASGS
STAQASASRQLTTALADASKEMKDMGDEYISTEHLLLGILDAAPNEAAKILEQNGITADKVRAAIPNVRGGAKVTSPDAE
ASYKALEKFSTDLTARAREGKLDPVIGRDQEIRRVIQILSRRTKNNPVLIGEPGVGKTAVVEGLAERIVAGDVPSTLQNK
RLISLDLGSMVAGSKYRGEFEERLKGVLDEIKQSDGQIITFIDEIHTIVGAGAAEGSMDAGNMLKPMLARGELRLIGATT
LDEYRENIEKDPALERRFQQVFVGEPSVEDTIAILRGLKQRYEAHHKVTIGDDALVAAATLSNRYITGRQLPDKAIDLVD
EAAAHLRMELDSQPEEIDELQRKVTRLEMEEMQLKKAEDPASKERLAKLQSELADAREKLAGLNARWNAEKEGHNKVGDL
RAQLDEKRVEADKATREGDLAKASRILYGEIPAIQKQLTEAEHEAEKEADFAHEDEPMVPDHVDADSVAGIVSEWTGIPV
GRLMQGENEKLLNMEEYLNRRVIGQPEAVRAVSDAVRRSRAGLSDPNRPTGSFLFMGPTGVGKTELAKALAEFLFDDEKA
MIRIDMSEYMEKSSVSRLIGAAPGYVGYEEGGQLTEAVRRRPYSVVLFDEVEKANSEVFDILLQVLDDGRLTDGQGRTVD
FKNTILIMTSNLGSQFLVNPDLDEQQKKDAVMNAVHSQFRPEFLNRLDDMVIFHPLTRQELGKIVDLQVKQVASRLTDRR
ITLDVTEAAREWLADTGYDPAYGARPLRRLVQTEVGDQLARMLLAGEIKDGDTVLVDHTGGEHLELTDHTHNPMEGDPNP
GDSQITVDDKKDDGEQKDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-164 46
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 6e-109 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-110 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-110 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_002469545.1 ATP-dependent chaperone ClpB VFG2084 Protein 1e-112 44
clpB YP_002469545.1 ATP-dependent chaperone ClpB VFG2076 Protein 3e-121 42