Gene Information

Name : leuS (BLA_1277)
Accession : YP_002470140.1
Strain : Bifidobacterium animalis AD011
Genome accession: NC_011835
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 1611623 - 1614589 bp
Length : 2967 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGTGAGAACGATACGAACGCGCAAGCAACATCGAATGCGCCGGCTACGCCACAATACCGCTATACGACGGAAATGGC
CCAGCGCATTGAGGAGAAATGGCAGGACATCTGGGAGAGCGAGGGCACGTTCTGGGCCGCGAACGTGAGCGGCGAACTCA
CTGACAGCAAGGGACGTCATGCCGATGGCCGTCAGTCCTTCTTCGCCATGGACATGTTCCCCTACCCTTCGGGCAAAGGA
TTACATGTCGGTCATCCGTTGGGATATCTGGCCACCGATGTGGTGAGCCGATACCATCGCATGAAGGGCGAGAACGTCCT
GCACGCCATGGGCTATGACGCATTCGGGCTTCCCGCCGAACAGTATGCCGTGCAGACGGGCCAGCACCCGCGCATCACGA
CCGAACAGAACATCGCGAATATGCGGCGACAGTTGCGCCGCATGGGGCTGAGCTTCGACGACCGCCGCTCCTTCGCCACG
ATCGAACCGGAATACGTGCGTTGGACCCAATGGATCTTCTCACGCATCTACGATGCCTGGTACGATCCGGATACGAGAAA
TCCGAGTGGATCCATGGGGTGCGCGCGCCCGATTTCCACCCTGATCGGACAATTCCGCGCCGGCACACGTCCGATTGACG
GACATGAGGACAAGGCCTGGGATGAACTCACCGAGATGGAGCAGACCGAGGTGCTCAATGAGTACCGACTCGCCTACATC
TCCAAATCGCCTGTCAATTGGTGCCCTGGGCTTGGCACGGTGCTCGCCAATGAGGAGGTCACTGCAGAGGGGCGTTCCGA
ACGTGGCAATTTCCCGGTGTTCCAGCGTGAGCTTCGTCAGTGGTCGATGCGCATCACCGCATACGGGCATCGTCTCATAG
AGGATCTCGATTCCATCGACTGGCCTGAGAAGGTCAAGCTCATGCAGCGCAACTGGATCGGGGAGTCGCATGGCGCCTCC
GTGCATTTCAAGGTGCCGGTCGACGGTGAGATGGCAGATATGGAGATCTACACCACACGACCCGACACGTTGTTCGGTGC
CACGTTCTGTGTGGTCTCTCCCGAACACCCGATGCTGGAGCATGTGCCCCAATCCTGGCCGGAAGGTGTGGACCCGGCGT
GGACGGGTGGCTATGCCACGCCGAGCGAGGCCGTATCCGCATACCGTGAGCTCGCGGAGGCAAAGACCGCGGCCGACCGT
GTGGCCGACAACGGTGAGAAGACGGGTTTGTTCACCGGCCTGTACGCGATCAACCCGATCACCGGTGCCAAGCTGCCGGT
GTTCACGGCCGACTATGTGCTCATGGACTATGGTACCGGTGCCATCATGGCCGTTCCGGGCGGTGACCAGCGAGACTACG
ATTTCGCCGTCAAGTACGGTCTTCCGGTGATCTACACGGTTGCGCCGCTCCCTGATTCCGGTGACGATCTGGCCAATTAT
GAGGGTACCGCCCCGTTCGTTTCGCATGACGGCATCGTCATCAATTCAGCCGTCGACGCGACGTGGGCCCGTGGCGACGC
GCTCTGCCTTGACGGCATGCGTGTGGATGATGCGATTGCTGCCGTCACCACGTGGCTCGAGGAGGCCCAGGTGGGCAAGG
GGGCCACGAGCTACCGTCTGCGCGACTGGCTCTTCAGCCGCCAACGGTATTGGGGTGAGCCGTTCCCGATTGTCTACGAT
GAGCATGAGGTGCCCCATCTGGTGCCCGACAGCATGCTGCCCATCAATCTGCCCGACGTTCCGGATTACAGCCCCAAGAC
CTTCGACCCGGAGGATTCCCAGTCGAGTCCGGAGGCCCCGTTGAGCCGCAACGAGGATTGGGTGAATGTCACGCTCGATC
TCGGTGACGGTCCGAAGACCTACCATCATGACACGAACACGATGCCGAATTGGGCTGGTTCCTGCTGGTACTACATGCGT
TACCTCAATCCCCATGACACCGAGCACATGGTGGAGCGCGACGAATACGACTATTGGATGGGTCCGAAGCACTCCCCGGC
GGCCGGGCAGGCCGGAGGCGTCGATCTGTATGTGGGCGGCGTGGAGCACGCGGTGCTACATCTGCTCTACTCACGGTTCT
GGCATAAGATCCTGTTCGACCTGGGGTACGTGGATTCGTTCGAACCGTTCCACAAGCTTTTCAACCAAGGCATGATCCAA
GCGTATGCCTACACCGATGACCGCGGTCAGTATGTGCCGGCCGAGGACGTTCAGGAGAGCGAAGTGGACGGCAAGACCGT
GTACACCTACGAAGGCGAACCGGTCAACCGTGAGTTCGGCAAGATGGGCAAGAGCCTCAAGAACATCGTGACCCCGGACT
ACATGTACGACCATTACGGCGCAGACACATTCCGCCTCTATGAGATGAGCATGGGACCGCTTGACGAGTCACGTCCATGG
AACACCCGCAATGTGGTGGGCGGCATGCGATTCCTGCAGCGTTTGTGGCGCAATGTGATTGATGAGAACACCGGCGAGGT
CACGGTGACCGACGACGCGATGGACGAACGTACGTTGAAACTGCTCAACAATACGATCGCCGAGGTGACCGGTGAGATGG
AGGCCATGCGTCCAAACACCGCCATCGCCAAACTCATCGTGCTCAACAATCACCTGACCGGCATGAACGGCGTGCCCCGC
GCCGCCGTGGAGCCGCTGGTGCTCATGGTGGCTCCGATCGCACCGCATATAGCCGAGGAGCTGTGGAACCGGCTCGGCCA
TGATGAGTCGTTGGCCCACCATCCATGGCCACAGGCCGACGAGCGTTATGTTGGGCAGGACACCGTCACCGCCGTGGTGC
AGATCAAAGGCAAGGTGCGGGCCAAACTCGAGGTGAGTGCCGACATCGACCCGGATGAACTGGAGAAGATGGCCTTGGAG
GCTGTGGCTGAGCGTCTTGGAGGCAAGCCGCCGCGCAAGGTGATCGTCAAGGCCCCGAAGATTGTTTCGATCGTCCCGGG
CGAATGA

Protein sequence :
MSENDTNAQATSNAPATPQYRYTTEMAQRIEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKG
LHVGHPLGYLATDVVSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMGLSFDDRRSFAT
IEPEYVRWTQWIFSRIYDAWYDPDTRNPSGSMGCARPISTLIGQFRAGTRPIDGHEDKAWDELTEMEQTEVLNEYRLAYI
SKSPVNWCPGLGTVLANEEVTAEGRSERGNFPVFQRELRQWSMRITAYGHRLIEDLDSIDWPEKVKLMQRNWIGESHGAS
VHFKVPVDGEMADMEIYTTRPDTLFGATFCVVSPEHPMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADR
VADNGEKTGLFTGLYAINPITGAKLPVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDDLANY
EGTAPFVSHDGIVINSAVDATWARGDALCLDGMRVDDAIAAVTTWLEEAQVGKGATSYRLRDWLFSRQRYWGEPFPIVYD
EHEVPHLVPDSMLPINLPDVPDYSPKTFDPEDSQSSPEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMR
YLNPHDTEHMVERDEYDYWMGPKHSPAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQGMIQ
AYAYTDDRGQYVPAEDVQESEVDGKTVYTYEGEPVNREFGKMGKSLKNIVTPDYMYDHYGADTFRLYEMSMGPLDESRPW
NTRNVVGGMRFLQRLWRNVIDENTGEVTVTDDAMDERTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPR
AAVEPLVLMVAPIAPHIAEELWNRLGHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELEKMALE
AVAERLGGKPPRKVIVKAPKIVSIVPGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 6e-139 45