Gene Information

Name : metB (BLA_1095)
Accession : YP_002469959.1
Strain : Bifidobacterium animalis AD011
Genome accession: NC_011835
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1393059 - 1394234 bp
Length : 1176 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACCAGGGCAGACACCAACTACGCTCACGACGGCATCGCGACCCGCGCAATCCATGCCGGGCAGGAACCGGACGCGCT
CACCGGCGCCGTCTCCACTCCCATCTACATGACCTCGACGTTCAAGCAGGACGGCGTGGGCGGATTGCGCGGCGGCTACG
ACTACTCACGGTCGGTGAACCCCACGCGCACGTCGTTCGACGAACAGCTTGCCGCAGTGGAGGGCGCGGCGTTCTCAATG
AGCTTCTCGTCGGGACTGGCGGCGATCGATGTGCTGCTGCGTGCCACAATGCGCCCGGGTGACTCGATTCTCATTGGCAA
CGACGTGTACGGCGGTACATATCGCCTGCTGTCCAAAGTGTTCGTGCCATGGGGCGTGGAACTCGACGTGGTGGATGCCA
CCGACGTCGCGGCGCTGAATGCGGCCCTGGGTGCCAAATCGTATCGGTATGTATGGGTGGAGACGCCATCGAACCCGCTG
CTTGGCATCACCGACATCGCATTGACGGCTCAGCTCGCCCATGAACACGGCACGAAAGTGGTGGTGGACAACACGTTCGC
ATCACCGATTCTGCAGCATCCGCTCGCGGATGGCGCCGACGCCGTGGTGTACTCCACCACCAAATACATCGGAGGCCACT
CGGACGTGGTCGGAGGGGCGGTGCTCGTCAACGACCCCGAGGTCGCCGACGCCGTGGCCTTCCTGCAGAACGCCGCCGGC
GCAGTGCCGTCTCCGTTCGATTCGTGGCTCGACATTCGCGGATTGAAAACACTTGGCCTGCGCGTGCGCAAACACAGTGC
GAATGCCTTGGAAATCGCGCAATGGCTGGAACGCCGCCCCGAGATCGAGCGCGTCTGGTACCCGGGCCTCGAGTCCCATC
CGGGTCACGAGATCGCCGCGCGGCAAATGCATGGCGGTTTCGGCGGCATGATCTCAGTGCAACTTGCCGGCGGCCCTGAA
GCGGCACAGCGTTTCGCCTCCTCGACGCGGCTGTTCACGCTCGCCGAGTCGCTTGGCGGCGTGGAATCGCTCATTGAAGT
GCCGGCGGCAATGACCCATGCCTCTGTTTCAGGCACAACACTCGAGGTTCCCGCCAACCTCGTGCGTCTGTCCATCGGCA
TCGAGGATGACGGCGATCTCATTGCCGACTTGGAGCAGGCACTGCAGCAGCTCTGA

Protein sequence :
MTRADTNYAHDGIATRAIHAGQEPDALTGAVSTPIYMTSTFKQDGVGGLRGGYDYSRSVNPTRTSFDEQLAAVEGAAFSM
SFSSGLAAIDVLLRATMRPGDSILIGNDVYGGTYRLLSKVFVPWGVELDVVDATDVAALNAALGAKSYRYVWVETPSNPL
LGITDIALTAQLAHEHGTKVVVDNTFASPILQHPLADGADAVVYSTTKYIGGHSDVVGGAVLVNDPEVADAVAFLQNAAG
AVPSPFDSWLDIRGLKTLGLRVRKHSANALEIAQWLERRPEIERVWYPGLESHPGHEIAARQMHGGFGGMISVQLAGGPE
AAQRFASSTRLFTLAESLGGVESLIEVPAAMTHASVSGTTLEVPANLVRLSIGIEDDGDLIADLEQALQQL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-73 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-74 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-56 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_002469959.1 cystathionine gamma-synthase BAC0207 Protein 1e-62 43