Gene Information

Name : smpB (BLA_1079)
Accession : YP_002469943.1
Strain : Bifidobacterium animalis AD011
Genome accession: NC_011835
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1374889 - 1375380 bp
Length : 492 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
GTGGCGAAGAAAGAGCAGAGCAACGAGAAGATGATCGCGCAGAACAGGCGCGCGCGGCACGACTACGAGATCGAAGACAC
CTATGAGGCGGGCCTTGCGTTGACGGGCACCGAGGTGAAGTCGCTGCGCGAGGGGCGTGCCTCGCTGGCGGAGTCGTTCA
TCTCGATTGACAAGCGGGGTGAGGTGTGGCTCGAAGGAGCGAACATTCCCGAATACCTCAACGGCACATGGAACAACCAT
GCGCCCAAGCGCAAACGCAAGCTGCTGCTGCACGGCGCGCAGATAGACAAGCTGCGCCGGCAGATTCAAGCGAAGGGCTA
CACCATTGTGCCGCTGCAGCTGTATTTCAACGAAGACGGCCGCGCGAAGCTCAAGATTGCGCTCGCCCGTGGCAAGAAGG
AGTACGACAAGCGGCAGGCGTTGCGTGAAGAGCAAGACAAGCGCGAGGCGTTGCGCATGATGCGCTACAAGAACATGCAT
GCCCGCGGCTGA

Protein sequence :
MAKKEQSNEKMIAQNRRARHDYEIEDTYEAGLALTGTEVKSLREGRASLAESFISIDKRGEVWLEGANIPEYLNGTWNNH
APKRKRKLLLHGAQIDKLRRQIQAKGYTIVPLQLYFNEDGRAKLKIALARGKKEYDKRQALREEQDKREALRMMRYKNMH
ARG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-32 55
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-29 52
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 6e-18 41