Gene Information

Name : thyA (BUAPTUC7_434)
Accession : YP_002468730.1
Strain : Buchnera aphidicola Tuc7
Genome accession: NC_011834
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 481371 - 482165 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAATACATCAAATTAATTAAAAAAATCATCAGGGTTGGAAACCAAAAAAAAGATCGCACAGGAACAGGAACTTT
ATCTATTTTTGGTTATAATATGAAATTTGATTTAAAAAAAGGTTTTCCACTTCTTACTACAAAAAAATGTCATATTGCAT
CTATCATCTACGAGCTTTTATGGTTTTTAAAAGGAGACACAAACATTGCTTATCTAAATGAAAATAAAATATCAATTTGG
AATAATTGGGCAAATGAATCCGGAGATGTTGGTCCAATATACGGAAAACAATGGCGTAATTGGAGTACACCAGAAGGACA
TGAAATTGATCAAATAAAAAATGTATTAATACAATTAAAAAAAAATCCCGATTCCCGTAGAATGTTAGTTTCTAGTTGGA
ATGTTGGAGATATAGATAAAATGAGATTACCTCCTTGCCATGTTTTATTTCAATTTTATGTATTTAACAATACATTAAGT
TGTCAATTGTACCAGCGTTCTTGTGATGTGTTTCTAGGACTACCTTTTAATATAGCTAGTTACTCAATACTTATACACAT
GATAGCACAACAATGTGATTTAAAAGTTGGAGATTTTTTGTGGACAGGAGGCGATGTTCACTTATATAATAATCATATAG
AATTAGCAAAAAAACAAATACTCAGAATACCTCGAACGCTTCCCAAACTAACCATCCTCAAAAAACCTCAGTCATTATTT
CAATATTGTTTCGAAGACTTTAAAATTATTGGATATCATCCTTATCCTGCTATCAAAGGAGAAATATCTATATAA

Protein sequence :
MKQYIKLIKKIIRVGNQKKDRTGTGTLSIFGYNMKFDLKKGFPLLTTKKCHIASIIYELLWFLKGDTNIAYLNENKISIW
NNWANESGDVGPIYGKQWRNWSTPEGHEIDQIKNVLIQLKKNPDSRRMLVSSWNVGDIDKMRLPPCHVLFQFYVFNNTLS
CQLYQRSCDVFLGLPFNIASYSILIHMIAQQCDLKVGDFLWTGGDVHLYNNHIELAKKQILRIPRTLPKLTILKKPQSLF
QYCFEDFKIIGYHPYPAIKGEISI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 9e-77 56