Gene Information

Name : Mpal_2637 (Mpal_2637)
Accession : YP_002467628.1
Strain : Methanosphaerula palustris E1-9c
Genome accession: NC_011832
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2764676 - 2766589 bp
Length : 1914 bp
Strand : +
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: sun:SU

DNA sequence :
ATGGGTCATTCATGTTCAAACAATTGCACTGATGATGATGGGGCGTATGATGGCGTTTGGTACGGTTTTCCCCCGCTCCG
TAATGCGCTGATAGCCGCAGTAATAGCAGTATCAGGATTCATTCTCGGTCTTCTCGGGATTATTCCGGAACTGGTCGTAA
CCCTGTTCTTCGTTGTCGCCATCCTCCTCGGGGCTTACCACTGGGCCCGGGAAGGATTTGAAGATCTGTTCCACGAGCAT
GCGATCGGCATTGAAATGCTGATGATCGCCGCCACACTGGGGTCGATCGTGCTCGAGCTCTGGGGAGAGGCCGTGACGCT
GGTCGTTCTGTACGCTGCAGCCGAAGGCGTAGAACATATCACCTACGCCCGGACGCGGGCATCGATACGGAAATTGCTTG
ATATTGCGCCGAAGGAAGCGGTCCTGATCAGGAGCGGGGACGAACAGGTGATCCCGGCCGAACAACTCAAGGTCGGGGAT
ATGTTCCTCGTGAAACCCGGGGCCGGCATCCCCACCGACGGCATCATCGTGAAAGGCCGGTCCAGTATCAACGAGGCCGC
GGTCACCGGTGAATCCATGCCTGTAGAAAAGCAGGAAGGTATGAAAGTCTTCGCTGCAACCTTCAATGTCGATGGTGCCC
TGGAAGTACGGGCGACAGCCACATTCAGTGACAATACCCTCACCAGGATGATCCACATGGTCGAAGAGGCACAGGAGCAG
AAGGGGAAGACCCAGGCCTTTATTGAGAGATTCGGGCGGAAATATACGCCGGCGGTCTTCTTCGTATCGCTCATGCTCAT
TCTCATTCCGCCGTTTTTCGGCATCCCGTTCAACGAGCTTGCGATACGGGGCGTAGTGCTTCTCATTGCAGCAGCACCGT
GCGCACTCGTCATGTCCACACCGGTTGCTGTTGCAGCCGGTATCGGGTCGGCAGGAAAGCACGGCATTCTCATCAAAGGA
GGTATCCACCTGGAGAATCTCGGGAAGACAAAGGCGGTTGCGTTCGACAAGACCGGGACCCTTACGACCGGGACTCCGGC
AGTGACCGATATCATCCCACTGAATGGTGATGAGCATGATGTCCTCCGGATCGCCTATACGATCGAGCGTTGCTCTGATC
ACCCGCTCGCCCGGGCCATTGTGATGCGTGCTGAGGTCGCTGGCATTCAGCCGCACGATGCAGTGGATCTATGCGCCCTT
GCCGGCCAGGCTGCAACGGCAACCATCGACGGGACGGTTTATTATGTGGGCAAACCGGAATTTTTTACCCGCGTGAATCC
TGACGCAGAGACGCAGCAGGAGATCGGCCGGCTTCGCTCTGACGGAAAGACGGTCATGTTCGTAGGGACGCAGGAGAGGA
TTCTCGGTCTCGTCGCGGTCAGGGATCAGGTCCGGCCGAATGCAAAGGCCACGATCGACCAGCTCCATGCGATGGGTATA
GCGACGATCATGCTGACCGGTGACAACCGAATCACAGCCAATGCCGTAGCTGCCAATCTTGGAATAGATGACATCCGGAC
CGATCTGAAGCCGGAAGACAAGACTGCTGCAATCGAGTCGCTCAAGGAGAAATACGGATCGGTCGTCATGATCGGCGATG
GCATCAACGATGCCCCGGCACTCGCCCAGGCAACCGTTGGTATCGCTATGGGTACGATCGGGACCGATGCGGCAATCGAA
GCGGCCGATGTGGCCCTGATGGCCGACGACCTGTCAAAAGTACCGGAAGCCATTGCGTTCGGGAAGAAAGCCCTTGCGGT
CTCCAATCAGAATATTGTCTTCTCGGTCGCGGTGCTCGCCATCCTTATCCCGGGCGCCCTTCTCGGGGTTCTCGGCGTAA
CGCTCGCGGTGATCTTCCATGAAGCGTCCGAACTCCTCGCGGTAGGAAACGGGCTGCGGGTTACAAAGCGGTGA

Protein sequence :
MGHSCSNNCTDDDGAYDGVWYGFPPLRNALIAAVIAVSGFILGLLGIIPELVVTLFFVVAILLGAYHWAREGFEDLFHEH
AIGIEMLMIAATLGSIVLELWGEAVTLVVLYAAAEGVEHITYARTRASIRKLLDIAPKEAVLIRSGDEQVIPAEQLKVGD
MFLVKPGAGIPTDGIIVKGRSSINEAAVTGESMPVEKQEGMKVFAATFNVDGALEVRATATFSDNTLTRMIHMVEEAQEQ
KGKTQAFIERFGRKYTPAVFFVSLMLILIPPFFGIPFNELAIRGVVLLIAAAPCALVMSTPVAVAAGIGSAGKHGILIKG
GIHLENLGKTKAVAFDKTGTLTTGTPAVTDIIPLNGDEHDVLRIAYTIERCSDHPLARAIVMRAEVAGIQPHDAVDLCAL
AGQAATATIDGTVYYVGKPEFFTRVNPDAETQQEIGRLRSDGKTVMFVGTQERILGLVAVRDQVRPNAKATIDQLHAMGI
ATIMLTGDNRITANAVAANLGIDDIRTDLKPEDKTAAIESLKEKYGSVVMIGDGINDAPALAQATVGIAMGTIGTDAAIE
AADVALMADDLSKVPEAIAFGKKALAVSNQNIVFSVAVLAILIPGALLGVLGVTLAVIFHEASELLAVGNGLRVTKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 3e-107 44
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 7e-105 44
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 6e-105 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mpal_2637 YP_002467628.1 heavy metal translocating P-type ATPase BAC0124 Protein 1e-75 41