Gene Information

Name : Mpal_2208 (Mpal_2208)
Accession : YP_002467227.1
Strain : Methanosphaerula palustris E1-9c
Genome accession: NC_011832
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2351880 - 2354471 bp
Length : 2592 bp
Strand : -
Note : KEGG: mbn:Mboo_1604 ATPase; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase

DNA sequence :
ATGAATTTCAACAATTTCACCATAAAATCACAGGAAACTGTAGCGAAAGCAACGGAACTTGCAACGACTAAACAGAACCA
GGTCATCGAGACTTCGCATCTCATGAGGGGGATGCTGTTGGTTGATGAGAATGTCATCCCATACCTGCTTAAAAAACTGA
ATGTGAACCTTGATGCTTTCACCGCAGAACTCGACAAGATCATCAGTTCATATCCCCAGGTGAGCGGAGGGGAGCAGTAT
CTCTCAAACGATGCCACAAAAGCACTGCAGAAAGCAATCGCACTTTCCCTGGAATCAAAGGATGAATTTGTCTCCCTTGA
GCACCTCCTCCTGGGAATTCTCTCGGTGAACGACCGTACTTCGCGGCTGCTAAAGGAGAACGGGGTTGCGGAGAAAGATC
TCAAGACGGCCATAAACCAGTTGCGGAAAGGTGCAACGGTGAACAACCAGGACGCGGAAGAGACCTATAATGCCCTGAAT
AGATTCGCCCGGAACCTGAATGATCTTGCCCGTACCGGGAAACTCGATCCGGTCATCGGGCGTAACGAAGAGATCCGCAG
GGTGTTGCAGATCCTTTCACGGAGAACAAAAAACAACCCGATCCTTATCGGGGAGCCCGGCGTGGGAAAAACGGCCATTG
CCGAAGGCCTCGCTCACCGGATCATCGACGGGGATGTACCGGAAAACCTGAAATCCAAGCAGATCTATTCCCTCGATATG
GGTGCCCTGATCGCCGGGGCAAAATTCAAGGGAGAGTTTGAAGAACGGCTGAAAAGTGTGATCAAGGAGGTGATCTCTGC
TGAAGGGGAAATAATTCTTTTCATTGACGAGATCCATACCCTGGTTGGGGCCGGCGGTGGTGAGGGCGCAATGGACGCTG
CCAATATTCTCAAACCCGCTCTATCACGAGGGGAATTACATGTTATCGGTGCAACGACCTTGAAAGAGTTCCAGAAATAT
TTTGAAAAGGATAAAGCGCTTGAGCGGCGTTTTCAGCCGGTGATGGTAAATGAACCGGATACGCTGGATGCCATTTCAAT
TCTTCGCGGAATCAAGGAGAAATACGAAACCCACCACCACGTTAGAATCAAGGATGAGGCCATCATCGCAGCCGTTGAAC
TTTCGCAACGCTATATCTCCGACCGATTTCTTCCTGACAAGGCAATTGACCTGATTGATGAGGCAGCATCAAAACTCCGT
CTTGAGATCAACTCGGTACCGGAAGAACTGGAAACGATAGAACGCAGGATCCGCCAGTTGGAAATTGAACGGGAAGCCAT
TAAACGTGAAAAAGACCAGGGCAAGTTGAAGGTTCTGAATGAAGAGATCGCAAACCTTACCGAGGAACGAAACAGGTTGA
AGGCAAAGTGGCAGGCTGAAAAAGAGATTGTAGAACAGATTCAGTCCCGAAAAAACGAGATTGAAGATCTGAAATTTGAA
GCCGAAAGTTGCCTCCGTACCGGCGAACTCGGCAAGGTGGCGGAGATCCGATATGGTCGTATCCCTGATATCGAGAAGGC
CATGGAAGGGCTTCAAGAAAAACAGGCCCTGTTGCAAAAGGATTCTGCGATGGTGAACGAGGAGGTGGACGCTGAGGAGA
TCGCCGAAGTGGTCTCCCGCTGGACTGGCATTCCCGTCAGTCGGATGCTGCAGAGTGAAAAACAAAAACTGCTGAGTCTC
GAGGTAGAACTACATAAGCGTGTTGTAGGTCAGGAGGAAGCCATTGGGGCAGTTTCTGATGCCATCCGCCGGAGTCGCGC
CGGTTTACAGGATACGAAACGTCCAATTGGGTCTTTCATCTTCCTGGGGACAACCGGTGTGGGAAAGACCGAACTGGCAA
AAGCCCTGGCTGAAATCCTTTTCAACAACGAAAACAGCATGGTGCGGATCGATATGTCGGAATACCAGGAACGGCATACC
GTTTCGAGGCTGATCGGAGCGCCCCCAGGCTATGTGGGATATGAAGAAAGCGGGCAACTGACAGAAGCTGTCCGGAGAAA
GCCCTATTCCGTGGTATTGCTGGATGAAATCGAAAAAGCCCATCCGGATGTCTTCAACATCCTGTTGCAGGTCCTTGATG
ACGGCCGTCTGACGGATAACAAGGGTCGCACGGTGGATTTCAAGAATACTATTATCATTATGACATCAAACATCGGGTCG
CACATCATCCAGGAGAACCTGGAAGAAGCCACCAATAAAAACAGGGATGAAGTATTCGACCGGACCCGAGAAGAGGTGTT
TGATCTGCTCAAGAAGACCATCCGTCCGGAGTTCCTTAACCGGATCGATGAGATCGTCATGTTCAAACCGCTCACGCAAG
ATGAGATCCAAACGGTTGTCGAGCTTCAACTGGGTCTGGTCCAGAAGATGCTTGAGAAGAGCGATATCCGGTTGAAGGTA
TCAAAGAACGCCATCACGTTAATCGCTATCCAGGGCTTTGACCCGCAATTTGGTGCTAGACCTATAAAACGTGTGATCCA
GAAAAACCTCCTGAATGAATTATCAAAAATGATCCTGGCAGGAAACGTAAACAAAGACAAGGAAATCGTGGTTGACGAGA
AAGAAGGGAAGTTAATGTTCATGAATGCCTGA

Protein sequence :
MNFNNFTIKSQETVAKATELATTKQNQVIETSHLMRGMLLVDENVIPYLLKKLNVNLDAFTAELDKIISSYPQVSGGEQY
LSNDATKALQKAIALSLESKDEFVSLEHLLLGILSVNDRTSRLLKENGVAEKDLKTAINQLRKGATVNNQDAEETYNALN
RFARNLNDLARTGKLDPVIGRNEEIRRVLQILSRRTKNNPILIGEPGVGKTAIAEGLAHRIIDGDVPENLKSKQIYSLDM
GALIAGAKFKGEFEERLKSVIKEVISAEGEIILFIDEIHTLVGAGGGEGAMDAANILKPALSRGELHVIGATTLKEFQKY
FEKDKALERRFQPVMVNEPDTLDAISILRGIKEKYETHHHVRIKDEAIIAAVELSQRYISDRFLPDKAIDLIDEAASKLR
LEINSVPEELETIERRIRQLEIEREAIKREKDQGKLKVLNEEIANLTEERNRLKAKWQAEKEIVEQIQSRKNEIEDLKFE
AESCLRTGELGKVAEIRYGRIPDIEKAMEGLQEKQALLQKDSAMVNEEVDAEEIAEVVSRWTGIPVSRMLQSEKQKLLSL
EVELHKRVVGQEEAIGAVSDAIRRSRAGLQDTKRPIGSFIFLGTTGVGKTELAKALAEILFNNENSMVRIDMSEYQERHT
VSRLIGAPPGYVGYEESGQLTEAVRRKPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDNKGRTVDFKNTIIIMTSNIGS
HIIQENLEEATNKNRDEVFDRTREEVFDLLKKTIRPEFLNRIDEIVMFKPLTQDEIQTVVELQLGLVQKMLEKSDIRLKV
SKNAITLIAIQGFDPQFGARPIKRVIQKNLLNELSKMILAGNVNKDKEIVVDEKEGKLMFMNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-102 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 5e-100 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 4e-100 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mpal_2208 YP_002467227.1 ATP-dependent chaperone ClpB VFG0079 Protein 1e-169 46
Mpal_2208 YP_002467227.1 ATP-dependent chaperone ClpB VFG2076 Protein 2e-122 45
Mpal_2208 YP_002467227.1 ATP-dependent chaperone ClpB VFG2084 Protein 3e-103 41