Gene Information

Name : Mpal_2131 (Mpal_2131)
Accession : YP_002467152.1
Strain : Methanosphaerula palustris E1-9c
Genome accession: NC_011832
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2262962 - 2264215 bp
Length : 1254 bp
Strand : -
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: mem:Mem

DNA sequence :
ATGGTTCAGAAATCAGTAACTGATAAGACCGTCTGTGTAGTCGGCCTCGGGTATGTGGGCTATCCACTGGCAGAAGCCTT
CTCGCATCATCTGAAGACGATTGGATTTGATATCGACGCACGGAAGATCGGGATCATCAACGAGACCCCTGGGAACAAGG
TCCAGGCAACCACTGATCCCTCTCATATTGGGGAGGCTGACATCATCATCATTGCCGTGCCGACACCGGTGACCAAGGCC
AAGGATCCTGACCTGATGCCGGTGATTTCAGCGGCTGAGACTATTGGGAAACATATCAAGAAGGGTGCCATCGTGGTCCT
CGAATCCACGGTCTACCCTGGGGTGACTGAGGAACTCATGGCCCCGATGATCGAGAAGATGTCTGGGTTTACCTGCGGAA
AGGAGTTCAAGATCGGGTACTCACCTGAGCGGATCAACCCTGGTGACGAGGAACACATCCTTCCAAAGATCACGAAGATC
GTCTCAGGGATGGATGAGGAGACCCTCGAAACACTCGCCTCGCTGTACAGCCTCGTGACCACGGTCTACCGTGCAGAGAA
CATCCGGACGGCTGAGGCTGCCAAGGTGATCGAAAACATCCAGCGTGACCTGAACATCGCCCTGATGAACGAGCTCTCGC
TGATCTTCCAGAAGATGGGTCTCGACACCCAGGCTGTCCTCGAGGCGGCGGGAACCAAGTGGAACTTCCACCATTACCGT
CCAGGTCTGGTCGGCGGTCACTGTATTCCGGTCGACCCCTACTACCTCGTCTACAAGGCAGAGGAGCTCGGGTACCACCC
TCAGGTGATCCTCGCCGGCCGTGCGATCAACGACTTCATGCCCAAGCATGTCGCAGAACTGGCTATCAAGGGGATGAACG
ACGCCGGCAAGGTGATCCGGGACTCGAAGGTGCTGATCCTCGGGCTCACCTACAAGGAGAATGTGCCTGACACCCGGGAG
AGCCCGTCCCATGAGATGATCAAGGAACTTCGGGAGTTCCGTGCTGATGTCTATGGGTATGATCCACTCCTTTCAGAGGC
CGACATCAACCAGTTTGGTGTGAAGCCTCTTAAGGATCTGAACGGGTTCAAGGCTGACTGTATCATCATCAATGTTCCGC
ATGATGCCTTCAAGTCGCTGACCCTTGAAGGGGTTGAAAAGATGAGCAACGGCACCCCGGTCGTCATCGATGTGAAGGGA
ATGCGCAAGCAGTGGGCCGATCCAGCCTGCAAGGTTTGCTATACCCGGCTCTAA

Protein sequence :
MVQKSVTDKTVCVVGLGYVGYPLAEAFSHHLKTIGFDIDARKIGIINETPGNKVQATTDPSHIGEADIIIIAVPTPVTKA
KDPDLMPVISAAETIGKHIKKGAIVVLESTVYPGVTEELMAPMIEKMSGFTCGKEFKIGYSPERINPGDEEHILPKITKI
VSGMDEETLETLASLYSLVTTVYRAENIRTAEAAKVIENIQRDLNIALMNELSLIFQKMGLDTQAVLEAAGTKWNFHHYR
PGLVGGHCIPVDPYYLVYKAEELGYHPQVILAGRAINDFMPKHVAELAIKGMNDAGKVIRDSKVLILGLTYKENVPDTRE
SPSHEMIKELREFRADVYGYDPLLSEADINQFGVKPLKDLNGFKADCIIINVPHDAFKSLTLEGVEKMSNGTPVVIDVKG
MRKQWADPACKVCYTRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-80 48
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-80 44
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 7e-80 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mpal_2131 YP_002467152.1 nucleotide sugar dehydrogenase VFG0431 Protein 3e-80 44