Gene Information

Name : Mpal_1156 (Mpal_1156)
Accession : YP_002466222.1
Strain : Methanosphaerula palustris E1-9c
Genome accession: NC_011832
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 1185942 - 1187102 bp
Length : 1161 bp
Strand : -
Note : PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mbn:Mboo_1991 cystathionine gamma-lyase

DNA sequence :
ATGGGGTTTGATACAAAAGCAATTCATGCCGGCGAAGAACCGGACCTTACAGGACATCCCAGCGGAGATGTCGTCGTTCC
GATTCACCTGGCGTCCACATTTGCCCGCCGGGATGTCGATGAGCCAACCGGGGGCTTTGAATATTCCCGAAGCGGAAACC
CCACGCGGTTTGCACTTGAACAGAAACTTGCTGCGATTGAGAACGCACGATTTGGCCTGGCATTCTCCTCAGGGCTGGCA
GCCGAGACCACGCTCTGCCTGAGCCTGCTCAGGGGAGGCGATCATGTGGTCGCCTTTGACGATCTCTATGGAGGGACGAG
GCGCCTTTTTAGCCAGGTGTTTCAGGAACAGTTCGATATCGAATTCTCGTTCGTCGACGCTCGGGACCCGGAGAATGTGA
AGGCAGCGATCCGGAAAAACACCCGTCTCATATGGCTGGAGTCGCCGACAAATCCTTTACTGAGACTCTGTGATATTCAG
GAGATCGCGAAAATCGCCCATGAAGCCGGGGCTCTCGTCGTCGTGGACAATACATTTGCAAGCCCGTATTTCCAGCATCC
AATCGAACGAGGGGCGGACGTCGTGGTGCACAGCACGACCAAGTACATCAATGGCCACAGCGATTCGGTGGGCGGGGCGC
TGATAACATCCGATGAAGACCTGAACAAAAAGTTCCGGTTTCACCAGAACGCGGCGGGGGCGATTCTCTCTCCGTTCGAC
AGTTTTCTCGTCTCCCGGGGGATCAAGACACTGGCATTGCGGATGGAACGGCATGAGAAGAATGCACTTCTGGTGGCGCA
GTTCTTATCAACGCACAAAAAAGTTGTTGCAGTCCATTATCCGGGTCTTGCATCGCATCCCCAGTATGCACTGGCACGAA
AACAGATGACCGGCTTCTCAGGTATGCTCTCCTTCGAACTGAAGGGCGGGGAGGCAGAGGCGAAGACGTTCCTCAGAAAC
CTGCGGTTATTCGCACTCGGAGAGAGCCTTGGTGGGGTCGAGTCCCTGATCGAGCACCCGGCAACAATGACCCATGCGTC
CATTCCATATGCAGAACGCCAAAAAGTGGGCGTGAGCGATTCCCTGGTTCGGATCTCCGTAGGTATCGAAAACGTGGAAG
ATCTCATTGCAGATCTCGATCAGGCATTGGGATCCATCTGA

Protein sequence :
MGFDTKAIHAGEEPDLTGHPSGDVVVPIHLASTFARRDVDEPTGGFEYSRSGNPTRFALEQKLAAIENARFGLAFSSGLA
AETTLCLSLLRGGDHVVAFDDLYGGTRRLFSQVFQEQFDIEFSFVDARDPENVKAAIRKNTRLIWLESPTNPLLRLCDIQ
EIAKIAHEAGALVVVDNTFASPYFQHPIERGADVVVHSTTKYINGHSDSVGGALITSDEDLNKKFRFHQNAAGAILSPFD
SFLVSRGIKTLALRMERHEKNALLVAQFLSTHKKVVAVHYPGLASHPQYALARKQMTGFSGMLSFELKGGEAEAKTFLRN
LRLFALGESLGGVESLIEHPATMTHASIPYAERQKVGVSDSLVRISVGIENVEDLIADLDQALGSI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-77 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-68 46
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-76 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mpal_1156 YP_002466222.1 cystathionine gamma-lyase BAC0207 Protein 1e-71 44