Gene Information

Name : smpB (Cagg_0655)
Accession : YP_002462027.1
Strain : Chloroflexus aggregans DSM 9485
Genome accession: NC_011831
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 810156 - 810632 bp
Length : 477 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCAACCAAAACGAACCATATCGCCGTCGTGGCGGAAAATCGCAAGGCACGTCACGATTACGATATTGAAGAGACTAT
CGAGGCCGGTATCGTGCTTTCCGGTAGCGAGATAAAATCGGTGCGCGCCGGCCGCGTTAATCTGCGCGGAAGTTTTGCCC
GCGTGATCGATGATGAAGTGTTTCTGTACGATGCCCATATCGCACCCTACGAGCAATCAGGTAAATATTTTAACCACGAT
CCACTGCGCCCACGGAAACTGCTGCTCCATCGCCGTGAAATTAACCGCTTGAACGGCCTGGTGCGGATGAAGGGAATGAC
GCTGGTGCCGTTGAAAATATATCTGAAAGGCCGACGGGCAAAAGTCGAGCTGGGTATCGCTCGTGGCAAGAAAATATACG
ATAAGCGTGAGGATATTGCGCGTCGCGATGCCGAACGTGATATCGAACGCGCATTGAAACGGCGAATACGTGAATAG

Protein sequence :
MATKTNHIAVVAENRKARHDYDIEETIEAGIVLSGSEIKSVRAGRVNLRGSFARVIDDEVFLYDAHIAPYEQSGKYFNHD
PLRPRKLLLHRREINRLNGLVRMKGMTLVPLKIYLKGRRAKVELGIARGKKIYDKREDIARRDAERDIERALKRRIRE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-25 63
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-19 50
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 3e-14 42