Gene Information

Name : Cagg_0312 (Cagg_0312)
Accession : YP_002461694.1
Strain : Chloroflexus aggregans DSM 9485
Genome accession: NC_011831
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 390245 - 391669 bp
Length : 1425 bp
Strand : -
Note : KEGG: cau:Caur_3128 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: HpcH/HpaI aldolase; Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence :
ATGCGTCGGACAAAAATTGTTGCTACGCTTGGGCCGGCGACGAGTACCCCCGAACGGATCGCCGGATTGATTCGTGCCGG
AATGAACGTGGCCCGTCTCAACTTCTCACATGGTACTCATGCCGAACACGCAGCGCGGATTGCGATGGTGCGACGAGCGG
CTGCCGAAGCCGGTCGCTATGTCGCTATTCTCCAAGATTTACAAGGACCGAAGATTCGCACCGGGCCACTGATTAACGGT
CAGCCGGTCGAGCTGGTTGCCGGTCAGCGCTTTGTAATCACGACCGAACCGATCGTCGGTGATGCTCAGCGCGTCAGTAC
CACCTACCGGGCCTTACCACTCGATGTGCGGCCACGAGACCGGATTTTGTTGTCGGATGGGTTAATCGAGCTGGTGGTCA
TCAACCATACCGACACTGAAGTTGAGACCGAGGTCGTGCATGGTGGAAAGTTACGCGAACATCAGGGCATCAATTTGCCG
GGTGTACGGGTCAGTGCGCCGGCCGCGACCGAGAAAGATCTTGCCGATCTCGCCTTTGGTCTCGAACAGGGTGTGGATTT
CGTGGCGTTGTCGTTTGTCCGCCGCGCCAGTGACGTGCGTGAGGTGAAGGAGTTCATTCGTCGAGCCGGAAAACAAACGC
CGGTCATTGCCAAGATTGAACGACCGGAGGCGCTTGAAGTTTTACCTGAGATCTTAGCCGAAGCTGACGGGATTATGGTG
GCCCGTGGTGATCTTGGTGTCGAAATGCCACCCGAACGGGTACCGATTGTACAGAAGCAGATTATCGCTGCGGCTAATCT
AGCGATGTTGCCCGTCATTACCGCCACTCAGATGCTCGAGTCGATGATTCACAACCCACGACCAACTCGCGCTGAAGCGA
GCGATGTGGCGAATGCGATTCTCGACGGTACCGACGCCGTGATGCTCAGCGGTGAGACGGCAGCCGGTGCGTACCCGATT
GAAGCCGTACAGATGATGGCGCTGATTGCCGATGCTGTCGAGTCATCGTTGAGCGGTAATCATTCACACACAACACCGCG
CTGGTCGGTTGTGTCTTCACAATCAACTCCACGTGCAATTGCTGCTGCGGCGTGTACTATTGCGAGTACCTTGCCGGTGC
GCTTTATCGTGGTGCTCACCCAGAGCGGCGCAAGTGCTCGGCTCGTCTCCCACTACCGGCCTGAAGTGCCGATCCTCGCC
TTCTGCCCGACCGAAGAGACGGCACGCCGCACGAGTCTCTACTGGGGTGTGACGCCCATTGTGATTGAGGCGCGTGACCG
ACTCGACGAACTGGAACAGCAGATCGTGCGGATGATGCGTAATATGGGGATGGCCCGGCGCGGTGATTTGATCGTCCTGA
GTGGCGGGCATCCGGTGTATCGCTACGGGCCAACCAACTTTTTAAAGGTCATTACGATTGAATAA

Protein sequence :
MRRTKIVATLGPATSTPERIAGLIRAGMNVARLNFSHGTHAEHAARIAMVRRAAAEAGRYVAILQDLQGPKIRTGPLING
QPVELVAGQRFVITTEPIVGDAQRVSTTYRALPLDVRPRDRILLSDGLIELVVINHTDTEVETEVVHGGKLREHQGINLP
GVRVSAPAATEKDLADLAFGLEQGVDFVALSFVRRASDVREVKEFIRRAGKQTPVIAKIERPEALEVLPEILAEADGIMV
ARGDLGVEMPPERVPIVQKQIIAAANLAMLPVITATQMLESMIHNPRPTRAEASDVANAILDGTDAVMLSGETAAGAYPI
EAVQMMALIADAVESSLSGNHSHTTPRWSVVSSQSTPRAIAAAACTIASTLPVRFIVVLTQSGASARLVSHYRPEVPILA
FCPTEETARRTSLYWGVTPIVIEARDRLDELEQQIVRMMRNMGMARRGDLIVLSGGHPVYRYGPTNFLKVITIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-75 47
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-75 47
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-75 47
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-75 47
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-53 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cagg_0312 YP_002461694.1 pyruvate kinase VFG0479 Protein 5e-76 47