Gene Information

Name : Cagg_2698 (Cagg_2698)
Accession : YP_002464002.1
Strain : Chloroflexus aggregans DSM 9485
Genome accession: NC_011831
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 3301170 - 3303374 bp
Length : 2205 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2

DNA sequence :
ATGATGCACAACCAGCAGTTTACGATTAAAGGAATGGATTGTCCCGATTGCGCGCGCACCGTCGAACGTGGGGTAGCCCG
GCTCGCAGGAGTGAAGACGTGTCATTTGAACTTCACTACTGAGCAGTTGCACGTCACCGGTGATGTTGACCCTGAAACAG
TTATTGCTCGTGTGCGTGAATTAGGGTATGAAGCCCAGCCGACGACATCCGCCGTGAGCGAGGCACCACCCTCATTCTTA
CGTTTTATGTTGAGTATTCGCGAGACAAAACGGGCACTCATCGGATTCCTCCTCGTCTTACCGGGGATCGTGTTGCACGA
GATACTCGGTTGGGAAGCGTGGTGGATTGACGCCCTCGCATTAGGTGGCTTGGCCCTCGTCGGGCCGTCAATTGCCCACC
ATGCATGGCGCGTGTTACGGACCAATCGGGAGTTGAGTATTGACGCCCTCATGACAATCGCGGCTATCGGTGCGATCGTC
ATCGGTGCGTATGTCGAAGCCGGCTTGGTGATGGTTCTCTATGCGATTGGCGAAGCGTTAGAGGGATACACAGCCAACCA
CGCCCGTCATACCATCCGCAGCCTGCTTGAGCTAACACCACCGACCGCTACGCTCATCACCCCTGACGGTGAACAGGTAA
CCGCCGTGGAGAACCTACACCCCGGCGACCGCATCATCGTCCGGCCTGGTGAGCGGGTCCCGGTTGATGGCACAATTACC
GCCGGGAGTTCGTTCGTCAATCAGGCACCGATTACCGGTGAAAGCCGCCTCGTCGAGCGGAGTGTCGGTGATGAAGTCTT
TGCCGGAACGATGAACGGCGAGGGAAGCATCGAAGTGATTGTAACGCGACCCGCTGCCGAGAGTACCGTAGCGCGCATGA
TCCATCTGGTGCAAGAAGCCCAAGAACGACGAGCACCGATTCAACGGTTCGTTGACCGCTTTGCCCGTATCTACACGCCA
TTGGTCGTTCTGCTTGCTGCCATTGTCGCGCTTGTGCCACCACTCTTCTTCGGCCAACCGTTCTGGAATCCAGACCCCAA
CACGTTTGGGTGGTTCTACCGTGGCTTAGCCTTACTCGTCGTCGCTTGCCCGTGCGCTTTAGTTATCAGTACGCCGGTGA
GTATTGTCAGTGCCCTAAGCACCGCTGCCCGCCACGGTGTTTTAATCAAAGGCGGTGCATATCTCGAAGCGTTGGCGCGC
GTACAGACGATTGCCATCGATAAGACCGGCACCCTCACGACCGGCAAACCGGCAGTCGTGACATTGCGCACAGTTGGCTG
CATCAAACCTGAGGCACCGCTCGGTCACTGTACGGCGTGTAATGAATTGTTAGCATTGGCCGGAGCGGTCGAGCGCCGTT
CAGAACACCCGCTGGCATATGCGATTGTCAATGCAGCCAACACGTGCGGCCTAACCTTGCCATCAGCGGCAGAGGTGCGC
ACCTTGGTTGGGCAGGGTGTCCGTGGGATAGTGAACGGTACTGAAGTATTTATCGGCAGTCATCGCACGTTTGATCAAGT
AATGACGCACGATGAATGGCACTGCCTTGCCGCACACCGCGATAGTCAGCTAGGCCGCACGCCGGTAATGGTCGGGGTCG
ACGGTCAATACCGTGGGACCATTACGGTAGCCGACACCATACGTGCGGAGAGTCGGAGTGCAATTGCCCGCCTCCGCGAT
CAGGGGCTGCGCATCGTGATGTTGACCGGTGATGAGACGGCCACTGCCGAGCGTATCGCTGCCGAATTGGGCGTCGATGA
CGTGCGGGCCGGTTTGTTACCGGCCGACAAAGCCCAAACCGTGCAAGCATTGCGCCAAACGAACGGTGTGGTGGCAATGG
TGGGCGATGGGATCAATGATGCACCGGCATTGGCTACAGCCGATGTTGGCATTGCCATCAGTGCGAGAGCCGGTGGGACA
ACGCAGGCAATGGAAACCGCCGACATAACCCTATTAAGCGGTGATCTGCATCAGTTGCCGTTTGCCATCGCGCTCAGCCG
CCAAACTCTACGCACCATCGCCACAAATGTCGCGTTTAGCATTGGGATCAAGCTTTTCTTCATCGGGCTGGTGCTCGCCG
GCCTCGGTACAATGTGGATGGCGGTCCTTGCCGATGTCGGTGCCTCGCTGCTCGTAACCCTAAACGGCATGCGCTTGTTG
CGTTTTCGGGCAAAATTACCGGTGGCATACGATCAAGCGGCGTGA

Protein sequence :
MMHNQQFTIKGMDCPDCARTVERGVARLAGVKTCHLNFTTEQLHVTGDVDPETVIARVRELGYEAQPTTSAVSEAPPSFL
RFMLSIRETKRALIGFLLVLPGIVLHEILGWEAWWIDALALGGLALVGPSIAHHAWRVLRTNRELSIDALMTIAAIGAIV
IGAYVEAGLVMVLYAIGEALEGYTANHARHTIRSLLELTPPTATLITPDGEQVTAVENLHPGDRIIVRPGERVPVDGTIT
AGSSFVNQAPITGESRLVERSVGDEVFAGTMNGEGSIEVIVTRPAAESTVARMIHLVQEAQERRAPIQRFVDRFARIYTP
LVVLLAAIVALVPPLFFGQPFWNPDPNTFGWFYRGLALLVVACPCALVISTPVSIVSALSTAARHGVLIKGGAYLEALAR
VQTIAIDKTGTLTTGKPAVVTLRTVGCIKPEAPLGHCTACNELLALAGAVERRSEHPLAYAIVNAANTCGLTLPSAAEVR
TLVGQGVRGIVNGTEVFIGSHRTFDQVMTHDEWHCLAAHRDSQLGRTPVMVGVDGQYRGTITVADTIRAESRSAIARLRD
QGLRIVMLTGDETATAERIAAELGVDDVRAGLLPADKAQTVQALRQTNGVVAMVGDGINDAPALATADVGIAISARAGGT
TQAMETADITLLSGDLHQLPFAIALSRQTLRTIATNVAFSIGIKLFFIGLVLAGLGTMWMAVLADVGASLLVTLNGMRLL
RFRAKLPVAYDQAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-100 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cagg_2698 YP_002464002.1 heavy metal translocating P-type ATPase BAC0298 Protein 5e-91 43
Cagg_2698 YP_002464002.1 heavy metal translocating P-type ATPase BAC0461 Protein 2e-85 41