Gene Information

Name : lysS (Cagg_2354)
Accession : YP_002463668.1
Strain : Chloroflexus aggregans DSM 9485
Genome accession: NC_011831
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 2864062 - 2865552 bp
Length : 1491 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTTGGTTATGGAATTAAACGACCTACAAGCCCAACGCGCTGCCAAACTCGAACAATTGCGCGCTGCCGGTCTCGATCC
ATACCCCCCACGTTGCCGGCGTAGCCATACGATCGGTCAAGTACTCGCTGCGTTTGATGAACTTGCCGCCGGTGAAGCCG
TCGTAACCCTCGCCGGGCGAATTATCGGGGCGCGCCGCGTGATGGGCAAGATTGCGTTTGCCCATATTGAAGACGGTACC
GGTGAAATTCAGCTCTGGCTGAGCCGAGCCGATCTCGGTGATGAGTGGTTTGAGCGCTTTCGCGACCAGATCGATACGTT
CGATATTGTCCAGGCAACCGGTACCCTCCGTCGCACTAAGACCGGTGAGCGGTCGTTATTCGTGCGCGAGATGGCCGTAT
TGGCTAAGGCGATTAATCCGCCACCGGAAAAGTGGGCCGGTCTGCAAGATGTCGAAGAGCGCCATCGTCAACGTTACCTC
GACCTGATCGTCAATCGCGAGCGACGCGATATTTTTCGTGCCCGTGCGCAGGTGATGAGCACGATGCGGCGCGTGCTTGA
CGATCGCGGCTTTCTTGAGGTCGAGACACCGGTTTTGCAACCGATCTACGGTGGTGCGGCTGCGCGTCCGTTTGTTACGT
ACCACAATGCACTTGGTCAGAATCTCTATCTCCGGATCGCCACAGAACTCTACCTCAAGCGGTTAATCGTCGGTGGTTTT
CCCGGCGTGTATGAGATCGGTAAAAACTTTCGCAACGAAGGTGTTGATCGATCCCACAACCCTGAGTTTACGATGATGGA
GTGTTATCAGGCGTATGCCGATTATCACGCCATGATGACCCTCGTCGAAGAGATGTTGGGTGAGATTTGTCTCGCCGTTC
ACGGCACGACAACGATTAGCTACCAGGGGCGCGAACTCGATCTTCGCCCGCCATGGCCGCGGATCGCAATGGCTGATGCG
ATTGTTGAGCGTACCGGTATCGATATTACCCGGCATACCGATCTGGATTCGTTGCACGCCGCGATTGCCGATCGTGGTCT
GCGGGTTGATCGGAAAACGTCATGGGCCAAACAGGTTGATGAACTCTTCTCGGAGTTTGTTCAGCCCCATCTTTTTCAGC
CTACGTTTATCATCGATTATCCGGTGGCGATGTCGCCGCTGGCTAAGCGGATTCCCGGTCGGCCCGATTTCACCGAACGC
TTTGAGGCGTTTATCGCCGGGATGGAGATCGGGAATGCGTTTACCGAGCTGAACGATCCCTTTGATCAGGAAGAGCGTTT
CCGCGAACAGTTACGGGCGTTTGCGGCCGGTGATGAAGAAGCCCATCAGATGGACGAAGATTTTATCAACGCCCTCCGCT
ATGGGATGCCGCCAACCGGTGGTCTTGGTATCGGGATCGATCGGTTGGTGATGGTTCTCACCGACCAGGCATCGATCCGT
GAAGTGATCCTCTTCCCGCATCTACGGGAACGGTTGGAAGGACGGGGATGA

Protein sequence :
MLVMELNDLQAQRAAKLEQLRAAGLDPYPPRCRRSHTIGQVLAAFDELAAGEAVVTLAGRIIGARRVMGKIAFAHIEDGT
GEIQLWLSRADLGDEWFERFRDQIDTFDIVQATGTLRRTKTGERSLFVREMAVLAKAINPPPEKWAGLQDVEERHRQRYL
DLIVNRERRDIFRARAQVMSTMRRVLDDRGFLEVETPVLQPIYGGAAARPFVTYHNALGQNLYLRIATELYLKRLIVGGF
PGVYEIGKNFRNEGVDRSHNPEFTMMECYQAYADYHAMMTLVEEMLGEICLAVHGTTTISYQGRELDLRPPWPRIAMADA
IVERTGIDITRHTDLDSLHAAIADRGLRVDRKTSWAKQVDELFSEFVQPHLFQPTFIIDYPVAMSPLAKRIPGRPDFTER
FEAFIAGMEIGNAFTELNDPFDQEERFREQLRAFAAGDEEAHQMDEDFINALRYGMPPTGGLGIGIDRLVMVLTDQASIR
EVILFPHLRERLEGRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 7e-100 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002463668.1 lysyl-tRNA synthetase VFG1668 Protein 4e-100 47