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Name : guaA (Cagg_1667) Accession : YP_002463004.1 Strain : Chloroflexus aggregans DSM 9485 Genome accession: NC_011831 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : - Position : 2033932 - 2035473 bp Length : 1542 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGACGACTCACAGTATTCCGGTGCTCGATTTTGGTTCCCAGACGGCGCAGTTGATCGTGCGGCGGCTGCGCGAATTGGG CTATTATAGCGAGTTGCTTGCACACGATGCGCCGGAAGCGCAGATCCGTGCGCTGAACCCGGTTGGAATTGTCCTTAGTG GTGGTCCGGCCAGTGTGTATGAGCCGGAGGCGCCAACTTTACCGCCATGGCTCATCGAAAGCAAGCTGCCCGTACTTGGA ATTTGCTACGGTATGCAACTAATCAGCCACACCCTCGGTGGTGTGGTGCGTCGTCCATCTGGGCGTGAGTACGGCCCGGC GATGATCACCGTCACCCAACCCCACCCACTTTTTGCCGATACCCCCACCGAACAGCCGGTCTGGATGAGTCATGGCGACC GAATCGAGCAGTTGCCCACCGGCTTTACGGCAATCGCCGCCAGCCAGGCCACGCCGTTTGCCGCCATTGCCGACGACCAC CGACGCTGGTACGGTGTCCAGTTTCACCCGGAAGTGGTGCATACCGTGTATGGGCGAGCACTTTTGACCAACTTTGCCAA ACTATGCGGGGCAAAACCCGAATGGCAGCCGAGCAGTTTTGTCACCGAAGCGATTGAACGGGTTCGAGCACAGGTCGGCC CACACGGGCGCGTCATCTGCGCCCTCTCCGGCGGGGTTGATTCGGCAGTGGCGGCTCTGATCATCCATCACGCTATCGGT GACCGGTTGACCTGCGTGTTCGTTGATAACGGCCTCTTGCGCGCCGGCGAAGCTGAACAGGTCATCAACACCTTTCGTGA ACATTTTCACGTACCGCTGATCGCAGTCGATGCGCGTGAAGAGTTTCTCGCTGCCTTAGAGGGTGTGGTTGATCCTGAGC AGAAGCGCAAGATTATCGGCGAGAAGTTTATTCGGATTTTCGAGCGCGAAGCGCGTTCGTTAGCAGACGTAGAGTTCCTC GCCCAAGGGACGCTCTACCCCGATGTAATCGAATCGACTGCACCGGACCGACCGAAGGCAGCAAAGATCAAAACGCATCA CAACGTTGGCGGGCTACCCGCCGACATGCAACTGAAGCTGGTTGAGCCGCTCCGCTACCTATTCAAAGATGAAGTACGCG CAGCAGGGCTGCAACTCGGCTTGCCCGAAGAGTGGGTATGGCGACATCCTTTCCCCGGACCCGGTCTCGCCGTGCGGATC ATCGGTACGGTAACGTGGGAACGGCTAGAGACATTGCGCAAAGCCGACAGCATCTTCCTTGAAGAGCTGCGGGCAAGCGG CTACTACCGTGCAACCCAACAGGCATTCGCCGTTCTCCTGCCGGTGCAAAGCGTCGGTGTGATGGGGGACGGGCGTAGTT ATGGTTTCACTATCGCACTGCGCGCGATTACCACCGAAGACTACATGACAGCCGACTGGGCGCGCTTACCCTACGAATTA CTGGCACACGTCAGTAGCCGAATTGTGAATGAGGTCGAAGGCGTCAATCGCGTCGTATACGATATTTCGTCGAAGCCACC GGCCACTATCGAGTGGGAGTAG Protein sequence : MTTHSIPVLDFGSQTAQLIVRRLRELGYYSELLAHDAPEAQIRALNPVGIVLSGGPASVYEPEAPTLPPWLIESKLPVLG ICYGMQLISHTLGGVVRRPSGREYGPAMITVTQPHPLFADTPTEQPVWMSHGDRIEQLPTGFTAIAASQATPFAAIADDH RRWYGVQFHPEVVHTVYGRALLTNFAKLCGAKPEWQPSSFVTEAIERVRAQVGPHGRVICALSGGVDSAVAALIIHHAIG DRLTCVFVDNGLLRAGEAEQVINTFREHFHVPLIAVDAREEFLAALEGVVDPEQKRKIIGEKFIRIFEREARSLADVEFL AQGTLYPDVIESTAPDRPKAAKIKTHHNVGGLPADMQLKLVEPLRYLFKDEVRAAGLQLGLPEEWVWRHPFPGPGLAVRI IGTVTWERLETLRKADSIFLEELRASGYYRATQQAFAVLLPVQSVGVMGDGRSYGFTIALRAITTEDYMTADWARLPYEL LAHVSSRIVNEVEGVNRVVYDISSKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 5e-138 | 55 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 3e-138 | 55 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 3e-138 | 55 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 3e-128 | 54 |
