Gene Information

Name : Cagg_1426 (Cagg_1426)
Accession : YP_002462769.1
Strain : Chloroflexus aggregans DSM 9485
Genome accession: NC_011831
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1756480 - 1757760 bp
Length : 1281 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGACATCAAACTCATCCGCGAGCAGCCCGATGAAGTAAAACGCCAATTGGCTCGCTGTGGTGTTGACGGTGCAAT
CATCGATCAGGTGCTAGCCTTCGATGAGCAACGGCGTCGTCTGATTTACGAAGTTGAAACGCGCAAAGCAGAGCGGAATG
CGGTCTCGAAGCAGATTGGTGCAATGAAAGATCAAGCCGAGCGACAGGCGAAGATTGAGGCAATGCGCCGATTGGGTGAT
GAGATCGCCGAACTCGATCGCCAACTCGCCGCCGTTGAAGAGCAGCAACGGGCAGCAATGTTGGAGATTCGCAACCTCCC
GCATCCTGATGTCCCCGATGGCGTTGATGAACACGATAACGTGGTTGTCTATCAAGAGGGAGAAGAACGTCAACTGCCGT
TTCCCGCTCGCCCACACTGGGAGCTTGGTGAAGCGTTGGGCATTCTCGACTTCGAGCGGGGCGTCAAGTTGGCCGGATCG
CGGTTTTACGTGATGCGTGGTGCCGGTGCGCGGCTGCAACGTGCGGTGATCCAGTGGCTGCTCGATCTCCATTTGCGGCA
GGGTTACCAAGAGATCTATACACCGTTTGTGGTGAAAGAGTCGGTGTTGTGGGCTTCGGGACAGTTACCGAAGTTCCGTG
ATAATCTCTACCGTGATGAGGAGTCGGGTTTGTGGCTGGTGCCGACGGCGGAAGTGCCGCTGACCGGTCTCTACGCCGAC
GAGATTCTGGAGGCGAGTCAGTTGCCGATCTACCACGCCGCCTATACGCCTTGTTTTCGGAAAGAACAGTTGAGTGCCGG
GCGTGATGTGCGGGGGATCAAGCGCGGTCACCAATTTGATAAGGTTGAGATGTACATGTTCGTGAAGCCGGAAGAGAGTT
ATCAGGCGCTCGAGAAGTTGCGTCGTGATGCCGAAGAGTGTGCGCGCTTGCTCGGTTTGCCGTTCCGCACGAAGCTGCTC
TGTACGGCTGATCTCGGGTTTGGTTCAACGAAGACCTACGATATTGAGGTATGGGCGCCGGGCGTGGGGGAGTGGCTTGA
AGTCAGCTCATGCTCTAACGTTGAAGCGTTTCAGGCTCGCCGTGCCAATATACGCTACCGGCCCGAACCGGGTGCCAAGC
CAGAGTTTGTCCATACGCTGAATGGATCAGGCCTTGGATTGCCGCGCACGATTATCGCGATTATGGAGAATTATCAACAG
GAAGACGGCAGTATTCTGATTCCCGAGGTGTTGCGCCCGTATATGGGTGGGATGGAACGGATTGTGAACGAAGCGGCGTA
A

Protein sequence :
MLDIKLIREQPDEVKRQLARCGVDGAIIDQVLAFDEQRRRLIYEVETRKAERNAVSKQIGAMKDQAERQAKIEAMRRLGD
EIAELDRQLAAVEEQQRAAMLEIRNLPHPDVPDGVDEHDNVVVYQEGEERQLPFPARPHWELGEALGILDFERGVKLAGS
RFYVMRGAGARLQRAVIQWLLDLHLRQGYQEIYTPFVVKESVLWASGQLPKFRDNLYRDEESGLWLVPTAEVPLTGLYAD
EILEASQLPIYHAAYTPCFRKEQLSAGRDVRGIKRGHQFDKVEMYMFVKPEESYQALEKLRRDAEECARLLGLPFRTKLL
CTADLGFGSTKTYDIEVWAPGVGEWLEVSSCSNVEAFQARRANIRYRPEPGAKPEFVHTLNGSGLGLPRTIIAIMENYQQ
EDGSILIPEVLRPYMGGMERIVNEAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-97 50