Gene Information

Name : Dhaf_0008 (Dhaf_0008)
Accession : YP_002456514.1
Strain : Desulfitobacterium hafniense DCB-2
Genome accession: NC_011830
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 9478 - 10743 bp
Length : 1266 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTAGATCTCAAATTTGTACGCACGAACCCCGAAGTAGTCAAGGAAGCCCTTAAAAAAAGAAATTCCAATGTCAGTTT
GGATGCTTTTCTGGAACAAGAAGAAGAGCGCCGCAAGCTTCTTTTTGAAGTGGAATCATTAAAAGCCCAGCGAAACACGG
TCTCTGAAGAGGTAGGGCGCCGGAAAAAACATGGGGAAGATGCGGAGCAGCTTATTTTAGAGATGCGGGAAGTGGGACAA
AAAGTTAAGAATCTCGAAGATAAATTAGGTGAGATTGAGCAGAGCATGGAAGCTGTGCTTTATGAGATTCCTAATATTCC
TCATGAATCAGTTCCAGTAGGAGCTGATGAAGAGGCCAATGTTGAGGTTCGCACCTGGGGAACTCCCCGCTCCTTTGATT
TTGAGCCTTTAGCTCATTATGAGATCGGCGAAAAGCTGGATATCCTGGATTTTGCCCGGGCAGGGAAGGTTACAGGAGCT
CGCTTTACTTTTTATAAAGGTTTAGGGGCCAAGCTGGAAAGAGCCCTGATCAGCTTCATGCTGGACCGGCATAGCGCTAA
AGGATATGTGGAAGTTCTGCCTCCTTATATGGTTCATCGTAATTCTATGATTGGTACCGGGCAGCTTCCTAAGTTTGAAG
AAGATGCTTTTAAGGTGGCGGGAACCGATTATTTCTTAATCCCTACTGCCGAAGTTCCGGTCACGAATATGTATCGGGAA
GAAATCCTGGAAGCCGAGCAATTGCCGATTCATCACTGTGCCTATAGTGCTTGTTTCCGTGCGGAAGCAGGTTCGGCAGG
CCGGGATACCCGGGGGCTCATCCGGCAGCATCAATTTAATAAAGTGGAACTGGTGAAGTTTGCCTTTCCTGAAAATTCCT
ATGAGGAGCTGGAGTCCTTAACCCGGGATGCGGAGAGTATTCTCCAGGAGCTTGAGCTTCCCTATCGGGTGATGGCTTTA
TCCACGGGGGATCTGGGCTTTACTTCAGCCAAGACTTACGATCTGGAAGTATGGCTGCCCAGCTTTAATACCTACCGGGA
GATTTCTTCCTGCAGCAATTTTGAAGATTTCCAGGCCCGCCGGGCCAATATCCGTTTCCGCCGGGCACCGAAAGCCAAGC
CTGAATTTCTCCATACTCTCAATGGCAGTGGTTTAGCCATTGGCCGTACGGTTTCCGCCATTCTTGAAAATTATCAGGAA
GCTGACGGCAGAGTGAGAGTTCCTAAAGCACTCCAGCCGTATATGGGCGTGGAGTACATTGGGTAG

Protein sequence :
MLDLKFVRTNPEVVKEALKKRNSNVSLDAFLEQEEERRKLLFEVESLKAQRNTVSEEVGRRKKHGEDAEQLILEMREVGQ
KVKNLEDKLGEIEQSMEAVLYEIPNIPHESVPVGADEEANVEVRTWGTPRSFDFEPLAHYEIGEKLDILDFARAGKVTGA
RFTFYKGLGAKLERALISFMLDRHSAKGYVEVLPPYMVHRNSMIGTGQLPKFEEDAFKVAGTDYFLIPTAEVPVTNMYRE
EILEAEQLPIHHCAYSACFRAEAGSAGRDTRGLIRQHQFNKVELVKFAFPENSYEELESLTRDAESILQELELPYRVMAL
STGDLGFTSAKTYDLEVWLPSFNTYREISSCSNFEDFQARRANIRFRRAPKAKPEFLHTLNGSGLAIGRTVSAILENYQE
ADGRVRVPKALQPYMGVEYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-126 62