Gene Information

Name : hemC (Dhaf_3354)
Accession : YP_002459808.1
Strain : Desulfitobacterium hafniense DCB-2
Genome accession: NC_011830
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3588725 - 3589651 bp
Length : 927 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGGGAAGCGTTAAAATAGGTACACGGGATAGTCAGCTGGCCCTTTGGCAAGCCGAATGGGTGAAAAGGAAACTGGAAGA
GTATTACCCGGAAAGAGAGTTTGTCCTGGTCCCCATGAAAACAAAGGGAGATAAGATTCTTGATGTCCCCCTTGCTAAAA
TCGGCGACAAGGGTCTTTTTACAAAAGAGTTGGAAGTTGGTCTTCTCAATGGGGAGATTGATTGTGCTGTTCATAGCCTC
AAGGATCTGCCTACGGTCTTGCCCCCAGGATTGGAAATCGCCGCTTTTTGCGAGAGAGAAGAGCCGCGGGATGTTTTTTT
AAGTAAAGACGGCACGCCTTTAGGGTCATTACCGGCCGGCTCAATCATCGGCACCAGCAGTTTAAGGCGCAAAGCCCAGC
TGCAGAATTATCGCTCCGATCTGTCTTTTGCGGATTTGCGCGGCAATCTCCAGACCCGTTGGCGGAAGCTCCAGGAGTCC
GATATGGCAGGTATCGTTCTGGCAGCGGCCGGTGTGAAACGCTTAGGCTGGGAAGACCGGATCACCGAATACATCTCTGA
AGAGATTATGCTTTCAGCAGTAGGCCAAGGAGCCATTGCTGTGGAGATTGCTGCCCAACGGGCTGATGTCAGGGAAATGC
TTGACTTGCTGAACCATGGGGATACGGAAAGAGCCGTCAAAGCAGAACGGGCTCTCCTCTACCGCTTGGAAGGGGGCTGT
CAGATTCCCATCGGAGCCTGGGCTGTGACAGAGCAGCAACAGATTGTTCTGAAGGGAATGGTCGCTTCCTTGGACGGTCA
ACGCATCCTGAAGGTCACTCTGTCGGGAGAGCATCCTGAAGAACTGGGCAGGCAAGCTGCCGATCTGCTGATTGCTCAAG
GAGCCCTGGAGATCCTGCAGGAGATTCGTACACCCTTAGAAAAGTAA

Protein sequence : 
MGSVKIGTRDSQLALWQAEWVKRKLEEYYPEREFVLVPMKTKGDKILDVPLAKIGDKGLFTKELEVGLLNGEIDCAVHSL
KDLPTVLPPGLEIAAFCEREEPRDVFLSKDGTPLGSLPAGSIIGTSSLRRKAQLQNYRSDLSFADLRGNLQTRWRKLQES
DMAGIVLAAAGVKRLGWEDRITEYISEEIMLSAVGQGAIAVEIAAQRADVREMLDLLNHGDTERAVKAERALLYRLEGGC
QIPIGAWAVTEQQQIVLKGMVASLDGQRILKVTLSGEHPEELGRQAADLLIAQGALEILQEIRTPLEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-61 48
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-61 48