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Name : vanB (Dhaf_1664) Accession : YP_002458146.1 Strain : Desulfitobacterium hafniense DCB-2 Genome accession: NC_011830 Putative virulence/resistance : Resistance Product : D-alanine--D-lactate ligase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1181 EC number : 6.3.2.4 Position : 1779555 - 1780580 bp Length : 1026 bp Strand : + Note : vancomycin B-type resistance protein; catalyzes the formation of D-alanyl-D-lactate in peptidoglycan synthesis DNA sequence : ATGAGTAAGTTGAAAATCGCAATTATCTTCGGAGGCTGTTCCGAAGAACATCCCGTCTCCGTTAAATCTGCTGGGGAGGT GGCCAAAAACCTGGATCTCGAAAAGTATGAACCCTTCTATATCGGGATTACGAAAGATGGGGTTTGGCAGCTTTGTCACT ACCCTGAGGCCAATTGGGAAAAGGGCAGTTGCCGTCCGGCTATCCTGTCACCGGACAGAAGCGTCCAGGGATTGCTTGTT CTGGAGCAGGGGCAATACCAAAGGATCCCCTTGGATCTGGTGTTTCCCGTTCTGCATGGCAAATTTGGCGAGGATGGCGC GATACAGGGTTTGTTGGAGCTTTCCGGCATCCCCTATGTGGGCTGCGATATCCCGAGTTCGGCTCTGTGCATGGACAAAT CCCTGGCTTATATCGTCGCTGGAAAGGCAGGAATTGCCACGCCAAAGTTCCGGACGGTCACTGCGAAGGAGACTATTGAC GCCGAACGGCTTGCTTATCCCGTTTATGTCAAGCCGGCCCGTTCGGGTTCATCCTTCGGCGTCACTAAGGTATGCCGCCA AGAAGAATTGCTGAGTGCGGTGGAAATCGCCAGACAGTATGACTCGAAGGTGCTGATTGAAGAGGCTGTCGTCGGCAGCG AGGTAGGCTGTGCGATATTTGGAAACGATCTGGATTTGATGGCCGGTGAGGTCGATCAGATCTGTCTGTCTCATGGCTTT TTCAGAATCCATCAGGAGAATGAGCCGGAAAAGGGTTCCGAAAACTCAACACTAATCGTTCCCGCCGACATTTCCCCAGA GGCGCGCTCGCGGGTTCAGGAGACGGCAAAAGCCATCTATCGCGCTTTGGGCTGCAGGGGACTGGCGCGGGTGGATATGT TTCTGAAAGAAGATGGAACAGTAATCCTCAACGAGGTGAATACTTTGCCCGGCATGACCTCATACAGCCGTTTTCCGAGA ATGATGGCGGCCGCAGGCTTGCCCTTTGCCGAAGTGATCGACCGGCTTGTCTCGTTGGCCTTTTAA Protein sequence : MSKLKIAIIFGGCSEEHPVSVKSAGEVAKNLDLEKYEPFYIGITKDGVWQLCHYPEANWEKGSCRPAILSPDRSVQGLLV LEQGQYQRIPLDLVFPVLHGKFGEDGAIQGLLELSGIPYVGCDIPSSALCMDKSLAYIVAGKAGIATPKFRTVTAKETID AERLAYPVYVKPARSGSSFGVTKVCRQEELLSAVEIARQYDSKVLIEEAVVGSEVGCAIFGNDLDLMAGEVDQICLSHGF FRIHQENEPEKGSENSTLIVPADISPEARSRVQETAKAIYRALGCRGLARVDMFLKEDGTVILNEVNTLPGMTSYSRFPR MMAAAGLPFAEVIDRLVSLAF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanB | NP_815951.1 | D-alanine--D-lactate ligase | Not tested | Not named | Protein | 2e-108 | 67 |
| vanB | YP_008394259.1 | Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase | Not tested | Not named | Protein | 8e-110 | 66 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| vanB | YP_002458146.1 | D-alanine--D-lactate ligase | AF310956.2.orf5.gene | Protein | 7e-109 | 67 |
| vanB | YP_002458146.1 | D-alanine--D-lactate ligase | U35369.1.gene6.p01 | Protein | 1e-108 | 67 |
| vanB | YP_002458146.1 | D-alanine--D-lactate ligase | AE016830.1.gene2250. | Protein | 1e-108 | 67 |
| vanB | YP_002458146.1 | D-alanine--D-lactate ligase | AY145441.gene.p01 | Protein | 5e-109 | 67 |
| vanB | YP_002458146.1 | D-alanine--D-lactate ligase | U00456.gene.p01 | Protein | 1e-108 | 67 |
| vanB | YP_002458146.1 | D-alanine--D-lactate ligase | AF277571.gene.p01 | Protein | 3e-112 | 66 |
| vanB | YP_002458146.1 | D-alanine--D-lactate ligase | AY489045.gene.p01 | Protein | 2e-109 | 65 |
| vanB | YP_002458146.1 | D-alanine--D-lactate ligase | NC_005054.2598280.p0 | Protein | 4e-108 | 65 |
| vanB | YP_002458146.1 | D-alanine--D-lactate ligase | NC_014475.1.orf3.gen | Protein | 4e-108 | 65 |
| vanB | YP_002458146.1 | D-alanine--D-lactate ligase | AF130997.1.orf4.gene | Protein | 4e-110 | 64 |
