Gene Information

Name : guaA (Dhaf_1438)
Accession : YP_002457928.1
Strain : Desulfitobacterium hafniense DCB-2
Genome accession: NC_011830
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1534661 - 1536193 bp
Length : 1533 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCTCAAGAACTCGTGTTGGTTCTGGATTTTGGTGGCCAATATAATCAGCTGATTGCTCGGCGTGTCAGAGAAGCTCA
TGTGTACTCGGAGATGATATCATATAAAACACCTGTGGAGGAGATTAAAGCAAGAAACCCCAAAGGAATTATTTTTTCCG
GCGGACCAGCCAGTGTCAATCAAGAAGGGGCACCCAAGGTGGATGAGGCCATTTATGAATTAGGCATTCCTATTTTCGGT
ATTTGTTATGGTATGCAGTTGATGACGGTTCAGCTAGGTGGAAAGGTAATGCATCCCGAAGTTCGGGAATATGGCAAAGC
CATGCTCCATGTAGATCAGGCCAAGGGCCTGTGGAAAGGCCTGGGGGGAGAACGCCAATGTTGGATGAGCCACGGGGACT
CAGTCACTGAGCTTCCTGAAGGCTTCGTTATCGCCGCTCATACAGACCATACCCCGGTAGCTGCTATGATGGACGAAACA
CGTCATTTTTACGGAGTACAGTTCCATCCGGAAGTAAAGCATACTCCAGACGGGCAGGCCATGCTTAAGCATTTTTTGTT
TGATATCTGCGGATGTCATGGGGAGTGGACGATGGAGTCCTTTATCGACGCCCAAGTCAAAGCTATTCGGGAGAAAGTGG
GAGATCGGCAGGTCCTTTGCGCCCTCAGCGGCGGTGTGGACTCCTCTGTAGCAGCCGTTCTTGTTCATAAGGCCATCGGC
GACCAACTGACCTGCGTCTTTGTGGATCATGGCTTTATGCGTAAAAATGAACCGGAACAGGTCAAGAAGATTTTTACGGA
GCAGTTCCATCTTAAGCTGATTTTTGTGGATGCCCGGGAGCGTTTTATGGCCAAGATCGGCGGAGTATCCGATCCTGAGA
CCAAACGGATCGGTATCGGCAATGAGTTCATCCGCCTTTTTGAAGATGAAGCCCGCAAATTAGGGCAGATTGATTTCTTG
GTTCAAGGCACTCTCTATCCGGATATTGTGGAGAGTGGTACGGATACCGCCGAAACCATCAAGAGCCATCATAATGTGGG
CGGACTTCCTGAAGATATGCAGTTTGAGCTGATTGAGCCGTTGGATATGCTTTTTAAGGATGAGGTTCGTGAAGTAGGTG
CTGAATTAGGTATCCCCGACGAGATCGTCTGGCGGCAGCCTTTCCCCGGACCGGGACTGGCGATTCGCATTATCGGCGAG
GTTACGGAAGAAAAGCTGGACATCCTTCGGGAGGCTGATGCCGTCATCGTGGAAGAAATCCGTAATGCAGGACTCTACAA
AGAGGTATGGCAATCCTTCGCTGTACTTCCTACCATAAAAAGCGTTGGCGTCATGGGAGATGGCCGGACTTACGCCTATC
CCATCGTTGTCCGCGCCGTGACCAGCGAGGATGCCATGACGGCGGACTGGGCAAGACTTCCCTATGACCTGATGGAGAAA
ATCTCCACCCGCATCGTCAACGAAGTGAAGGGTGTCAATAGGGTAGTGTATGACATTACCTCAAAACCTCCTGGGACCAT
CGAGTGGGAGTAA

Protein sequence :
MAQELVLVLDFGGQYNQLIARRVREAHVYSEMISYKTPVEEIKARNPKGIIFSGGPASVNQEGAPKVDEAIYELGIPIFG
ICYGMQLMTVQLGGKVMHPEVREYGKAMLHVDQAKGLWKGLGGERQCWMSHGDSVTELPEGFVIAAHTDHTPVAAMMDET
RHFYGVQFHPEVKHTPDGQAMLKHFLFDICGCHGEWTMESFIDAQVKAIREKVGDRQVLCALSGGVDSSVAAVLVHKAIG
DQLTCVFVDHGFMRKNEPEQVKKIFTEQFHLKLIFVDARERFMAKIGGVSDPETKRIGIGNEFIRLFEDEARKLGQIDFL
VQGTLYPDIVESGTDTAETIKSHHNVGGLPEDMQFELIEPLDMLFKDEVREVGAELGIPDEIVWRQPFPGPGLAIRIIGE
VTEEKLDILREADAVIVEEIRNAGLYKEVWQSFAVLPTIKSVGVMGDGRTYAYPIVVRAVTSEDAMTADWARLPYDLMEK
ISTRIVNEVKGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-161 62
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-161 62
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-161 62
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-145 58