Gene Information

Name : Dhaf_1383 (Dhaf_1383)
Accession : YP_002457875.1
Strain : Desulfitobacterium hafniense DCB-2
Genome accession: NC_011830
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1488375 - 1489505 bp
Length : 1131 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: mta:Moth_1989 cysteine synthase / cystathionine gamma-synthase

DNA sequence :
ATGAATATTTTAACCGAACTGGCTCAGATCGGCAATCGCCGGGATCCTTACGGGGCGATCAGCTTTCCTGTTTACCATTC
ATCTACCTTTGCTCACCCCGGCTTCGGCCAAAGCACAGGCTTTGATTACTCACGAACCGGCAATCCCACCCGCCAAGCTT
TAGAAGATGCTATGGCAAGCCTGGAAGAGGGTACCAAAGGGTTTGCTTTTTCCTCAGGCATGGGTGCCATCACTACCATC
CTCTCCTTATTCTCTCAGGGCGAGCATCTTCTCGTCACCGAAGATCTCTATGGAGGAACCTACCGTATCCTTGAGGAGGT
CTTCAGCCGCTTTGGCCTCCAAGTCACTTTTGTTGATTCCAGTGATCTCGACACCATCGCAAAAGAGATCCGCCCCCACA
CAAAAGCCATCTTCACCGAAACACCTACCAACCCTCTAATGAAGATTGCCGACCTAAAGGGGATCGCTTCCTTGTGCCAG
AAGCACGGTCTCTTAAATATAGTGGACAATACTTTTCTTACACCCTATTTGCAAAAACCACTGAACTTGGGAGCAGACAT
TGTTATTCATAGTGGCACCAAATATCTTGGCGGCCATAATGATGTCGTGGCGGGCCTCGTCGTGGTTCAAGGAGAAGAGC
TTGCAGCTCGCTTTGGACGTTTGCAGAACTCTCTCGGCGCTACATTGGGCCCCCAAGATTCCTGGCTAATTATCCGGGGA
TTGAAAACCTTGGCCCTGCGCATGAGAGCACAAGAAGAAAATGCCCTCCAGATTGCACAATGGCTGGAGACGCATCCCCT
TGTCACCGCGGTCTGTTATCCCGGACTTAAGCATCATCCCGGCTATGCAACTCAGCTTGAACAAGCCCGGGGCTTCGGTG
CTATGCTATCTTTCCGGGTAAAAAGTCCCAGCTTAATCCCCGAGATATTAAAATCCCTCAAAATTATCTCCTATGCGGAA
AGCCTTGGTGGTGTAGAATCTCTAATCACTTATCCCGCTACCCAAACCCATGCCGATATCCCTCACGAAGTAAGGACAAG
GCTTGGGGTGGACGATTGTCTTCTCCGGTTATCACTGGGTATTGAAGCCGCCGAGGATCTCATTGGCGATTTAGAACAAG
CTTTAAAATAG

Protein sequence :
MNILTELAQIGNRRDPYGAISFPVYHSSTFAHPGFGQSTGFDYSRTGNPTRQALEDAMASLEEGTKGFAFSSGMGAITTI
LSLFSQGEHLLVTEDLYGGTYRILEEVFSRFGLQVTFVDSSDLDTIAKEIRPHTKAIFTETPTNPLMKIADLKGIASLCQ
KHGLLNIVDNTFLTPYLQKPLNLGADIVIHSGTKYLGGHNDVVAGLVVVQGEELAARFGRLQNSLGATLGPQDSWLIIRG
LKTLALRMRAQEENALQIAQWLETHPLVTAVCYPGLKHHPGYATQLEQARGFGAMLSFRVKSPSLIPEILKSLKIISYAE
SLGGVESLITYPATQTHADIPHEVRTRLGVDDCLLRLSLGIEAAEDLIGDLEQALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-90 48
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-91 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-67 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dhaf_1383 YP_002457875.1 cystathionine gamma-synthase BAC0207 Protein 1e-61 43