Gene Information

Name : BCAH820_0091 (BCAH820_0091)
Accession : YP_002449117.1
Strain : Bacillus cereus AH820
Genome accession: NC_011773
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 89700 - 92135 bp
Length : 2436 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGATGTTTGGAAGATTTACAGAAAGAGCACAGAAAGTATTAGCTTTATCTCAAGAGGAAGCAATTCGTATTGGGCATAA
CAATATTGGAACAGAACATATTTTACTTGGGCTTGTACGCGAAGGTGAAGGAATTGCAGCAAAAGCGTTGATTGCTCTTG
GATTAAGTCCAGAGAAGGTTCAAAAAGAAGTAGAAGCGTTAATCGGACGTGGAACAGAAGCTTCTCAAACTGTACATTAT
ACACCGCGTGCTAAAAAGGTTATTGAGCTGTCTATGGATGAAGCTCGTAAATTAGGTCATTCTTACGTTGGAACAGAACA
TATTTTACTTGGTTTAATCCGCGAAGGTGAAGGGGTAGCGGCACGCGTTTTAAATAACTTAGGTGTTAGCCTAAATAAGG
CAAGACAACAAGTATTGCAACTTCTTGGAAGTAATGAAGCAAGTTCAGGTCACCAAGGTGGTTCTTCAACAAATGCAAAT
ACACCAACACTTGATAGCTTAGCACGTGATTTAACAGTTGTTGCACGTGAAAATCGTTTAGACCCTGTTATTGGACGTGG
TAAAGAAATTCAACGTGTAATTGAAGTTTTAAGCCGTAGAACAAAAAACAATCCTGTATTAATCGGGGAGCCTGGTGTAG
GTAAAACGGCAATTGCGGAAGGATTAGCACAACAAATCGTAAATAATGAAGTTCCTGAAACTTTACGAGATAAGCGTGTT
ATGACACTAGATATGGGTACAGTGGTAGCTGGAACGAAATACCGTGGTGAATTTGAAGACCGTTTGAAGAAAGTAATGGA
TGAAATTCGCCAAGCGGGAAATATCATTCTATTTATTGATGAACTTCATACATTAATCGGTGCAGGTGGAGCAGAAGGTG
CTATTGACGCATCGAATATTTTAAAACCATCTTTAGCTCGTGGGGAATTACAATGTATCGGGGCGACAACGTTAGATGAA
TATCGCAAATATATTGAAAAAGACGCAGCTTTAGAGAGACGTTTCCAACCAATTCACGTTGATGAGCCAAGTTTAGATGA
ATCAACTCAAATTTTGAAAGGTTTACGCGATCGTTATGAGGCACATCACCGCGTATCTATTACAGATGATGCAATTGATG
CAGCTGTAAAGCTTTCAGATCGTTATATTACAGATCGTTTCTTACCAGATAAAGCAATTGATTTAATTGATGAAGCTGCT
TCAAAGGTTCGCTTACGCTCTTATACAACACCACCAAATCTAAAAGAGCTTGAAGTGAAGCTTGAGGAAATTAGAAAAGA
AAAAGATGCAGCTGTACAAAGTCAAGAGTTTGAAAAAGCTGCTTCCTTACGTGATATGGAACAACGTTTACGCGAGAAGT
TAGAAGATACGAAGCGTCAATGGAAAGAACAACAAGGAAAAGAAAACTCAGAAGTGACAGTAGAAGATATTGCAAATGTT
GTTTCTACATGGACTCGTATCCCGGTTTCTAAACTTGCACAAACAGAGACTGATAAATTATTAAACTTAGAATCCATCCT
TCACGATCGTGTTATTGGTCAAGATGAAGCGGTAGTAGCTGTAGCGAAAGCTGTTCGCCGTGCTAGAGCAGGATTGAAAG
ATCCGAAACGTCCAATTGGGTCATTTATTTTCTTAGGGCCAACAGGTGTAGGTAAAACGGAGCTAGCAAGAGCGTTAGCA
GAATCTATGTTCGGTGATGAAGATGCAATGATTCGCATCGATATGTCTGAGTACATGGAGAAGCATTCTACTTCTCGTTT
AGTTGGGTCTCCTCCAGGGTATGTTGGATATGAAGAAGGTGGACAATTAACAGAAAAGGTTCGCCGTAAGCCATATTCAG
TTGTCTTATTAGACGAAGTAGAGAAAGCTCATCCTGATGTGTTTAACATTTTACTACAAGTATTAGAAGATGGTCGCTTA
ACAGATTCGAAAGGGCGTACGGTTGATTTCCGCAATACAATTGTTATTATGACATCTAACGTTGGTGCAGAGGCGTTAAA
ACGTAATAAGCATCTTGGATTTAACGTACAAGATGAGAGCCGCGATTATTCGGATATGAAAGGTAAAGTAATGGATGAGC
TGAAAAAAGCCTTCCGTCCAGAATTCTTAAACCGTATTGATGAAATTATCGTGTTCCATATGCTTGAGAAAAAACATATT
CAAGAGATTGTAACACTTATGGTAAATCAGTTAGTAAATCGCTTAAAAGAGCAAGAAATTGAATTGCATTTAACAGAAGG
AGCAATTTCGGCTATTGCTGATAAAGGGTTTGATCGAGAGTACGGTGCTCGCCCGCTTCGTAGAGCGATTCAGAAACATG
TAGAAGATAGACTATCCGAAGAACTGTTAAAAGGTGCTATTGAGAAAGGACAGAAAGTTATCTTTGATGTTGAAGGAGAA
TCATTTGTCATTCATAGTGCCGAAAAGGTAAAATAA

Protein sequence :
MMFGRFTERAQKVLALSQEEAIRIGHNNIGTEHILLGLVREGEGIAAKALIALGLSPEKVQKEVEALIGRGTEASQTVHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNEASSGHQGGSSTNAN
TPTLDSLARDLTVVARENRLDPVIGRGKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPSLDESTQILKGLRDRYEAHHRVSITDDAIDAAVKLSDRYITDRFLPDKAIDLIDEAA
SKVRLRSYTTPPNLKELEVKLEEIRKEKDAAVQSQEFEKAASLRDMEQRLREKLEDTKRQWKEQQGKENSEVTVEDIANV
VSTWTRIPVSKLAQTETDKLLNLESILHDRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESMFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIVIMTSNVGAEALKRNKHLGFNVQDESRDYSDMKGKVMDELKKAFRPEFLNRIDEIIVFHMLEKKHI
QEIVTLMVNQLVNRLKEQEIELHLTEGAISAIADKGFDREYGARPLRRAIQKHVEDRLSEELLKGAIEKGQKVIFDVEGE
SFVIHSAEKVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BCAH820_0091 YP_002449117.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 77
BCAH820_0091 YP_002449117.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 5e-148 52