Gene Information

Name : megL (BCAH820_4772)
Accession : YP_002453718.1
Strain : Bacillus cereus AH820
Genome accession: NC_011773
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 4519569 - 4520747 bp
Length : 1179 bp
Strand : -
Note : catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine

DNA sequence :
ATGAAAAAGAAGCATATGGAGACAGCGTTAATTCATCACGGTTATACATCAGAGGAACATAAAGGAAGTTTAACACCGCC
TTTATTTCAAACGTCTACATTTACATTTGAGACTGCGCAGCAAGGAGAGGCGAGTTTTGCGGGAGTGGATCCATCTTATA
TTTACTCAAGACTTGGAAATCCGACTGTGAAATTATTTGAAGAACATATGGCGGTGTTAGAAGGTGGAGAAGAAGCTCTT
GCTTTCGGATCCGGAATGGCAGCTATTTCAGCAACTTTAATTGGTTTTCTAAAAGCTGGAGATCATATTATTTGTTCAAA
TGGATTATACGGATGCACGTACGGTTTTTTAGAAGTGTTAGAAGAAAAATTTATGATTACGCATTCGTTTTGTGATATGG
AGACAGAGGGTGATATTGAAAATAAAATTCGCCCAAATACAAAGCTTATTTTCGTTGAAACACCGATTAATCCGACAATG
AAATTAATTGATTTAAAACAAGTGATTCGGGTTGCGAAGCGAAATGGTTTACTTGTCATTGTTGACAATACGTTTTGTTC
ACCTTATTTACAAAGACCGCTTGAACTTGGCTGTGACGCCGTTGTTCATAGTGCGACAAAATATATTGGTGGTCACGGTG
ATGTTGTAGCGGGTGTAACAATTTGTAAAACGAAAGCGTTAGCTGAAAAAATTCGCCCGATGCGAAAAGATATCGGCGGT
ATTATGGCACCGTTTGATGCGTGGTTATTGTTACGCGGATTAAAGACACTAGCGGTAAGAATGGACCGCCATTGTGATAA
TGCAGAAAAAATTGTATCGTTCCTAAAAAATCATGATGCGGTAGAAGGTGTTTGGTATCCAGAAGGGGAGTTAGCATCTC
GCCAAATGAAACGTGGGGGCGGCGTTATATCTTTTTCAATTAAAGGCGGGAAAGAAGAGACGCAGGCGTTTATTAATGAC
CTTCACTTTATTACAATTGCGGTGAGTTTAGGAGATACAGAAACGTTAATTCAGCATCCGGCAACGATGACGCACGCTGC
GATTCCAGCTGAGTTAAGACAAGAAATGGGCATTTATGATAATTTAATACGTTTATCTGTCGGTTTAGAATCGTGGGAGG
ATATCGTTTCTGATTTAGAGCAGGCATTAAAGAAAATATCTACGGTTAGTAACCAATAA

Protein sequence :
MKKKHMETALIHHGYTSEEHKGSLTPPLFQTSTFTFETAQQGEASFAGVDPSYIYSRLGNPTVKLFEEHMAVLEGGEEAL
AFGSGMAAISATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEGDIENKIRPNTKLIFVETPINPTM
KLIDLKQVIRVAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTKALAEKIRPMRKDIGG
IMAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWYPEGELASRQMKRGGGVISFSIKGGKEETQAFIND
LHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALKKISTVSNQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-66 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-67 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
megL YP_002453718.1 methionine gamma-lyase BAC0207 Protein 4e-89 48