Gene Information

Name : guaA (BCAH820_0294)
Accession : YP_002449294.1
Strain : Bacillus cereus AH820
Genome accession: NC_011773
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 261515 - 263053 bp
Length : 1539 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGAAGAAGCAGCATGATACAATTATCGTTTTAGATTTTGGGAGTCAATACAATCAGTTAATAGCACGTCGAATTCGTGA
GTTCGGTGTATACAGTGAACTTCATCCACATACAATTACTGCGGAAGAAATTAAAGCAATGAATCCAAAAGGGATTATCT
TCTCTGGTGGACCAAATAGTGTATACGGTGAAGGTGCATTACATTGTGATGAAAAAATCTTTGACCTAGGATTACCGATC
TTCGGTATTTGTTACGGTATGCAACTTATGACACAACAATTCGGTGGTACAGTAGAACGTGCAAACCACCGTGAGTACGG
AAAAGCTGTTCTTAAAGTAGAGAACGAATCAAAATTATATGCGAACCTTCCAGAAGAGCAAGTTGTATGGATGAGCCATG
GCGACTTAGTAACTGGTTTACCTGAAGGATTCGTAGTAGACGCAACAAGTGAGTCTTGCCCAATTGCTGGTATGAGCAAT
GAAGCGAAAAACTTATACGGTGTACAATTCCACCCAGAAGTACGTCACTCTGAGCACGGTAACGATTTAATTAAAAACTT
CGTATTCGGCGTATGTGGTTGTTCTGAAGGATGGAACATGGAAAACTTTATCGAAGTAGAATTAGAAAAAATCCGTGAAA
CTGTTGGAGACAAAAAAGTACTATGCGCACTTAGTGGCGGTGTAGACTCTTCTGTTGTAGCAGTATTAATTCATAAAGCA
ATCGGTGATCAGTTAACGTGTATTTTCGTTGACCATGGTTTACTTCGTAAAGGCGAAGCAGAAGGCGTTATGAAAACATT
TAGCGAAGGCTTCCATATGAACGTTATTAAAGTGGATGCAAAAGAACGCTTCATGAACAAGTTAAAAGGTGTAGAAGATC
CAGAACAAAAACGTAAAATTATCGGTAACGAATTCATTTACGTATTTGATGATGAAGCTTCTAAATTAGAAGGAATGGAC
TTCTTAGCACAAGGTACACTGTACACAGATATCGTTGAAAGTGGTACAGCAACTGCACAAACAATTAAATCTCACCATAA
CGTTGGTGGACTTCCAGAAGACATGCAGTTCAAATTAATTGAGCCTTTAAATACGTTATTTAAAGACGAAGTACGTGTAT
TAGGATCTGAACTAGGAATTCCTGATGAAATCGTATGGCGTCAACCATTCCCAGGCCCTGGTCTTGGTATTCGTGTATTA
GGTGAAATCACAGAAGAGAAATTAGAAATCGTTCGTGAATCTGATGCGATTTTACGTGAAGAAATTATTAAAGCAGGATT
AGACCGCGAAATCTGGCAATACTTCACTGCGCTTCCTGGTATGCGTAGCGTAGGTGTTATGGGTGACGAGCGTACTTACG
ATTACACAGTAGGTATCCGTGCAGTAACATCTATTGACGGTATGACAGCTGACTGGGCACGTATCCCTTGGGACGTATTA
GAGAAAATCTCTGTACGTATCGTAAACGAAGTAAAACACGTTAACCGTATCGTGTATGATGTAACGAGTAAGCCACCAGC
AACGATTGAGTGGGAATAG

Protein sequence :
MKKQHDTIIVLDFGSQYNQLIARRIREFGVYSELHPHTITAEEIKAMNPKGIIFSGGPNSVYGEGALHCDEKIFDLGLPI
FGICYGMQLMTQQFGGTVERANHREYGKAVLKVENESKLYANLPEEQVVWMSHGDLVTGLPEGFVVDATSESCPIAGMSN
EAKNLYGVQFHPEVRHSEHGNDLIKNFVFGVCGCSEGWNMENFIEVELEKIRETVGDKKVLCALSGGVDSSVVAVLIHKA
IGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFHMNVIKVDAKERFMNKLKGVEDPEQKRKIIGNEFIYVFDDEASKLEGMD
FLAQGTLYTDIVESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRVLGSELGIPDEIVWRQPFPGPGLGIRVL
GEITEEKLEIVRESDAILREEIIKAGLDREIWQYFTALPGMRSVGVMGDERTYDYTVGIRAVTSIDGMTADWARIPWDVL
EKISVRIVNEVKHVNRIVYDVTSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 74
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 74
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-140 55