Gene Information

Name : BCG9842_B5224 (BCG9842_B5224)
Accession : YP_002443628.1
Strain : Bacillus cereus G9842
Genome accession: NC_011772
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 89449 - 91884 bp
Length : 2436 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGATGTTTGGAAGATTTACAGAAAGAGCACAGAAAGTGTTAGCTTTATCTCAAGAGGAAGCAATTCGTATTGGGCATAA
TAATATTGGAACAGAACATATTTTACTTGGGCTTGTACGCGAAGGTGAAGGAATTGCAGCAAAAGCATTAATTGCTCTTG
GATTAAGTCCAGAGAAAGTTCAAAAAGAAGTAGAAGCGTTAATTGGGCGAGGAACAGAAGCTTCTCAAACTGTACATTAT
ACACCTCGTGCTAAAAAGGTTATTGAATTATCTATGGATGAAGCGCGTAAGCTAGGCCATTCTTACGTTGGAACAGAACA
CATTTTACTCGGTTTAATCCGTGAAGGTGAAGGTGTAGCCGCACGTGTTTTAAATAATTTAGGTGTAAGTCTAAATAAAG
CAAGACAACAAGTGTTACAACTTCTTGGAAGTAATGAAGCTAGTTCAGGTCATCAAGGTGGTTCAGCAACAAATGCAAAT
ACACCGACACTGGACAGTTTAGCAAGGGACTTAACAGTTGTTGCACGTGAAAATCGCTTAGACCCTGTTATTGGACGCGG
TAAAGAAATTCAACGTGTAATTGAGGTATTAAGCCGTAGAACGAAAAATAACCCAGTATTAATTGGTGAGCCTGGTGTAG
GTAAAACGGCAATTGCAGAAGGATTAGCACAGCAAATTGTAAATAATGAAGTTCCTGAAACTTTAAGAGATAAGCGTGTT
ATGACACTAGATATGGGTACAGTGGTAGCTGGAACAAAATATCGCGGTGAATTTGAAGATCGTTTAAAGAAAGTGATGGA
TGAAATTCGCCAAGCAGGCAATATTATTCTATTTATTGATGAGCTTCATACATTAATTGGTGCAGGTGGAGCAGAAGGTG
CAATCGATGCATCGAATATTTTAAAACCATCTTTAGCACGAGGAGAGCTACAATGTATTGGGGCAACAACTTTAGATGAG
TATCGTAAATATATTGAAAAAGACGCGGCTTTAGAAAGACGTTTTCAACCAATTCATGTTGATGAGCCAAGTTTAGAAGA
ATCGATTCAAATCTTGAAAGGTTTACGTGATCGTTATGAGGCGCATCACCGTGTATCTATTACAGATGACGCTATTGATG
CAGCTGTAAAACTTTCAGATCGTTATATTACAGATCGCTTTTTACCGGATAAAGCAATTGATTTAATTGATGAAGCTGCT
TCAAAAGTTCGCTTACGTTCTTATACAACACCACCAAACTTAAAAGAGCTTGAAGTGAAGCTTGAGGAGATTCGAAAAGA
AAAAGATGCAGCTGTACAAAGTCAAGAATTTGAAAAGGCTGCATCCTTACGTGATATGGAGCAACGCTTACGTGAGAAGT
TAGAAGATACAAAACGTCAATGGAAAGAGCAACAAGGAAAAGAAAATTCAGAGGTTACGGTAGAAGATATTGCAAATGTC
GTTTCTACATGGACGCGTATCCCAGTTTCTAAACTTGCACAAACAGAGACTGATAAATTATTAAATTTAGAATCCATTCT
TCATGATCGTTTGATTGGTCAAGATGAAGCAGTAGTAGCAGTAGCAAAAGCTGTTCGTCGTGCAAGAGCAGGATTAAAAG
ATCCGAAGCGCCCGATTGGTTCATTTATTTTCTTAGGACCAACAGGTGTAGGTAAAACAGAACTTGCAAGAGCACTAGCA
GAATCTATGTTCGGTGATGAAGATGCAATGATTCGCATCGATATGTCAGAGTATATGGAGAAGCATTCTACTTCCCGTTT
AGTTGGTTCTCCTCCAGGATATGTTGGATATGAAGAAGGTGGACAATTAACAGAGAAAGTTCGTCGCAAGCCATATTCAG
TTGTATTATTAGATGAGGTAGAGAAAGCTCATCCGGATGTATTTAATATTCTACTACAAGTATTAGAAGATGGTCGTTTA
ACAGATTCTAAAGGACGTACAGTTGATTTCCGTAATACAATTGTTATTATGACGTCTAACGTTGGTGCCGAGGCGTTAAA
ACGTAACAAACATCTTGGATTTAATGTCCAAGATGAAAGCCGTGATTATTCGGATATGAAAGGTAAAGTAATGGATGAGT
TGAAAAAGGCATTTCGTCCAGAATTCTTAAACCGTATTGATGAAATTATCGTATTCCATATGCTTGAGAAAAAACATATT
CAAGAGATTGTAACTCTTATGGTAAATCAGTTAGTAAATCGCTTAAAAGAACAAGAAATCGAATTGCACTTAACGGAAGG
GGCAATTTCAGCTATTGCAGATAAAGGATTTGATCGTGAGTATGGCGCTCGTCCACTTCGCAGAGCAATTCAGAAACATG
TAGAAGATAGACTATCAGAAGAACTTTTAAAAGGTGCTATTGAGAAAGGACAAAAAGTTATCTTTGATGTAGAAGGAGAA
TCATTTGTCATTCATAGTGCGGAAAAGGTAAAATAA

Protein sequence :
MMFGRFTERAQKVLALSQEEAIRIGHNNIGTEHILLGLVREGEGIAAKALIALGLSPEKVQKEVEALIGRGTEASQTVHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNEASSGHQGGSATNAN
TPTLDSLARDLTVVARENRLDPVIGRGKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIHVDEPSLEESIQILKGLRDRYEAHHRVSITDDAIDAAVKLSDRYITDRFLPDKAIDLIDEAA
SKVRLRSYTTPPNLKELEVKLEEIRKEKDAAVQSQEFEKAASLRDMEQRLREKLEDTKRQWKEQQGKENSEVTVEDIANV
VSTWTRIPVSKLAQTETDKLLNLESILHDRLIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESMFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTIVIMTSNVGAEALKRNKHLGFNVQDESRDYSDMKGKVMDELKKAFRPEFLNRIDEIIVFHMLEKKHI
QEIVTLMVNQLVNRLKEQEIELHLTEGAISAIADKGFDREYGARPLRRAIQKHVEDRLSEELLKGAIEKGQKVIFDVEGE
SFVIHSAEKVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BCG9842_B5224 YP_002443628.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 78
BCG9842_B5224 YP_002443628.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 4e-148 51