Gene Information

Name : megL (BCG9842_B0472)
Accession : YP_002448220.1
Strain : Bacillus cereus G9842
Genome accession: NC_011772
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 4581537 - 4582712 bp
Length : 1176 bp
Strand : -
Note : catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine

DNA sequence : 
ATGAAAAAGAAGCATATGGAGACAGCGTTAATTCATCACGGTTATACACCTGAGGAACATAAAGGAAGTTTAACACCACC
TTTATTTCAAACTTCTACATTTACATTTGAGACTGCGCAGCAAGGAGAGGCGAGTTTTGCGGGAGTGGATCCATCTTATA
TTTACTCACGGCTTGGAAATCCAACTGTGAAATTATTTGAAGAACGTATGGCGGTGTTAGAAGGAGGAGAAGAGGCACTT
GCCTTCGGATCTGGTATGGCAGCTATTTCAGCAACTTTAATTGGTTTTTTAAAGGCTGGAGATCATATTATTTGTTCAAA
CGGATTATATGGGTGTACGTACGGTTTTTTAGAAGTGTTAGAAGAAAAATTTATGATTACGCATTCGTTTTGTGACATGG
AGACAGAGGCTAATATTGAAAATAAAATTCGTTCGAATACAAAGCTTATTTTCGTTGAAACACCGATTAATCCAACAATG
AAATTAATCGATTTAAAACAAGTGATTCAGGTTGCGAAGCAAAATGGCTTACTTGTCATTGTTGATAATACGTTTTGTTC
GCCTTATTTACAAAGACCGCTTGAGCTTGGCTGTGACGCTGTTGTGCATAGTGCGACAAAATATATTGGTGGCCATGGTG
ACGTTGTAGCGGGTGTAACGATTTGTAAAACGAAAGCGTTAGCTGAAAAGATTCGCCCGATGCGAAAAGATATCGGCGGT
ATTATGGCGCCGTTTGATGCGTGGTTATTATTACGCGGGTTAAAGACGTTAGCAGTAAGAATGGATCGTCATTGTGATAA
TGCAGAAAAAATTGTATCGTTCTTAAGAAAACATGATGTGGTAGAAGATGTTTGGTATCCAGAAGGGGAGTTAGCATCTC
GTCAAATGAAACGCGGGGGCGGTGTTATTTCTTTTTCAGTAAAAGGCGGAAAAGAAGAGACGCAAGCGTTTATTAATGAT
CTTCACTTTATTACAATTGCGGTAAGTTTAGGCGATACAGAAACATTAATTCAGCATCCAGCAACGATGACGCACGCTGC
GATTCCGGCTGAACTAAGAAAAGAAATGGGCATTTTCGATAATTTAATACGCTTATCGGTCGGTTTAGAATCGTGGGAGG
ATATCGTTTCTGATTTAGAGCAGGCATTAAAGAAAATATCTACTGTTAATCAATAA

Protein sequence : 
MKKKHMETALIHHGYTPEEHKGSLTPPLFQTSTFTFETAQQGEASFAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEAL
AFGSGMAAISATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEANIENKIRSNTKLIFVETPINPTM
KLIDLKQVIQVAKQNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTKALAEKIRPMRKDIGG
IMAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLRKHDVVEDVWYPEGELASRQMKRGGGVISFSVKGGKEETQAFIND
LHFITIAVSLGDTETLIQHPATMTHAAIPAELRKEMGIFDNLIRLSVGLESWEDIVSDLEQALKKISTVNQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-68 43
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-66 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
megL YP_002448220.1 methionine gamma-lyase BAC0207 Protein 2e-89 48