Gene Information

Name : guaA (BCG9842_B5024)
Accession : YP_002443790.1
Strain : Bacillus cereus G9842
Genome accession: NC_011772
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 251438 - 252976 bp
Length : 1539 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGAAGAAGCAACACGATACAATTATCGTTTTAGATTTTGGAAGTCAATACAATCAGTTAATAGCACGTCGAATTCGTGA
GTTCGGTGTATACAGTGAACTTCATCCACATACAATTACTGCAGAAGAAATTAAAGCAATGAATCCAAAAGGGATTATTT
TCTCTGGTGGACCAAATAGCGTATACGGTGAAGGTGCATTACATTGTGATGAAAAAATCTTCGAACTAGGATTACCGATT
TTCGGTATCTGTTACGGTATGCAGCTTATGACACAACACTTCGGTGGTAAAGTAGAGCGTGCCAACCACCGTGAGTACGG
AAAAGCTGTTCTTAAAGTAGAGAACGAATCAAAATTATATGCGAACCTTCCAGAAGAGCAAGTTGTATGGATGAGCCATG
GCGACTTAGTAACTGGTTTACCTGAAGGATTTGTAGTAGACGCAACAAGTGAGTCTTGTCCAATTGCTGGTATGAGCAAT
GAAGAGAAAAACTTATACGGTGTACAATTCCACCCAGAAGTACGTCACTCTGAGCACGGTAACGATTTAATTAAAAACTT
CGTATTCGGTGTATGTGGTTGTTCTGAAGGATGGAACATGGAGAACTTTATCGAAGTAGAACTAGAGAAAATTCGTGAAA
CTGTTGGAGACAAAAAAGTACTATGCGCACTTAGCGGCGGTGTAGACTCTTCTGTTGTAGCAGTATTAATTCATAAAGCA
ATCGGCGATCAATTAACATGTATTTTCGTTGACCATGGTTTACTTCGTAAAGGTGAAGCGGAAGGCGTTATGAAAACATT
CAGCGAAGGCTTCCACATGAACGTTATTAAAGTGGATGCACAAGAACGTTTCATGAACAAGTTAAAAGGTGTAGAAGATC
CAGAACAAAAACGTAAAATCATTGGTAATGAATTCATTTACGTATTTGATGATGAAGCTTCTAAATTACAAGGTATGGAC
TTCTTAGCACAAGGTACACTTTACACAGACATCGTTGAAAGTGGTACAGCAACTGCACAAACAATTAAATCTCACCATAA
CGTTGGTGGACTTCCAGAAGACATGCAGTTCAAATTAATTGAGCCTTTAAATACGTTATTTAAAGATGAAGTACGTGTAT
TAGGATCTGAACTAGGAATTCCTGATGAAATCGTATGGCGTCAACCATTCCCAGGTCCTGGTCTTGGTATTCGTGTATTA
GGTGAAATCACAGAAGAGAAATTAGAAATCGTTCGTGAATCTGATGCGATTTTACGTGAAGAAATTATTAAAGCAGGATT
AGACCGCGAAATCTGGCAATACTTCACTGCGCTTCCTGGCATGCGTAGCGTAGGTGTTATGGGTGACGAGCGTACTTACG
ATTACACAGTAGGTATCCGTGCAGTAACATCTATTGACGGTATGACAGCTGACTGGGCACGTATCCCTTGGGACGTACTA
GAGAAAATCTCTGTTCGTATCGTAAACGAAGTAAAACACGTTAACCGTATCGTGTATGATGTAACGAGTAAGCCACCAGC
AACTATTGAGTGGGAATAG

Protein sequence :
MKKQHDTIIVLDFGSQYNQLIARRIREFGVYSELHPHTITAEEIKAMNPKGIIFSGGPNSVYGEGALHCDEKIFELGLPI
FGICYGMQLMTQHFGGKVERANHREYGKAVLKVENESKLYANLPEEQVVWMSHGDLVTGLPEGFVVDATSESCPIAGMSN
EEKNLYGVQFHPEVRHSEHGNDLIKNFVFGVCGCSEGWNMENFIEVELEKIRETVGDKKVLCALSGGVDSSVVAVLIHKA
IGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFHMNVIKVDAQERFMNKLKGVEDPEQKRKIIGNEFIYVFDDEASKLQGMD
FLAQGTLYTDIVESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRVLGSELGIPDEIVWRQPFPGPGLGIRVL
GEITEEKLEIVRESDAILREEIIKAGLDREIWQYFTALPGMRSVGVMGDERTYDYTVGIRAVTSIDGMTADWARIPWDVL
EKISVRIVNEVKHVNRIVYDVTSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 74
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-139 55