Gene Information

Name : thyA (BCG9842_B3105)
Accession : YP_002445616.1
Strain : Bacillus cereus G9842
Genome accession: NC_011772
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2083892 - 2084848 bp
Length : 957 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACATGCTGAAAATGAATACTTAAATTTATGCCGCCATGTAATGGAACATGGTACGAAGAAAGAAGATCGTACAGG
GACAGGAACTGTATCTGTATTTGGATATCAAATGCGTTTTGATTTGAGTAAAGGATTTCCTTTATTAACGACAAAAAGAG
TACCATTTCGCCTTGTAGCAAGTGAACTACTTTGGTTTATGAAAGGTGATACAAATATTCGCTATTTATTGCAGCATAAT
AATAATATTTGGAATGAATGGGCATTTAAGGGCTGGGTGGAAAGTGACGAGTATACTGGTCCTGACATGACTGATTTTGG
TCTTCGCTCACAACAAGATGAAGAATTTAAAGTACAGTACGATGAGCAAATGGAATTGTTTAAAAAGAACGTTTTAGAAG
ATGATGATTTCTCAAATAAATATGGTTATTTAGGAGACGTATACGGTAAACAGTGGCGTGCTTGGAAAACGACAGCCGGT
GAGACACTTGATCAATTAAAAGATGTAATTGAAATGATTAAAAAAACACCAGACTCACGTCGTTTAATCGTTTCTGCTTG
GAATCCTGAAGACGTACCGAGTATGGCATTACCGCCTTGTCATACATTATTCCAGTTTTATGTAGCGGACGGAAAACTTT
CTTGTCAGTTATATCAAAGAAGTGGTGACATATTCCTTGGAATTCCATTTAACATCGCAAGTTATGCACTACTAACACAT
TTAATTGCACATGAATGTGGTCTTGAAGTAGGAGAATTTGTTCATACAATTGGAGATGCACACATTTATACAAATCATTT
TGAACAAGTAGAAAAGCAATTGGCACGTGAACCACGTCCGTTCCCGAAACTTACATTAAATTCAGATGTGAAATCTGTTT
TCGATTTTGAAATGGAAGATTTAACGATTGAAGGATACGATCCGCATCCAGCAATTAAAGCACCGGTTGCAGTATAA

Protein sequence :
MKHAENEYLNLCRHVMEHGTKKEDRTGTGTVSVFGYQMRFDLSKGFPLLTTKRVPFRLVASELLWFMKGDTNIRYLLQHN
NNIWNEWAFKGWVESDEYTGPDMTDFGLRSQQDEEFKVQYDEQMELFKKNVLEDDDFSNKYGYLGDVYGKQWRAWKTTAG
ETLDQLKDVIEMIKKTPDSRRLIVSAWNPEDVPSMALPPCHTLFQFYVADGKLSCQLYQRSGDIFLGIPFNIASYALLTH
LIAHECGLEVGEFVHTIGDAHIYTNHFEQVEKQLAREPRPFPKLTLNSDVKSVFDFEMEDLTIEGYDPHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 4e-106 66