Gene Information

Name : hemC (PLES_56541)
Accession : YP_002443232.1
Strain : Pseudomonas aeruginosa LESB58
Genome accession: NC_011770
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 6257422 - 6258363 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTCGTCCCGCGAAATCCGCATCGCCACTCGCCAGAGCGCCCTCGCCTTGTGGCAGGCCGAATACGTCAAGGCGCGCCT
GGAACAGGCGCATCCCGGCTTGACCGTCACCCTGCTGCCGATGACCAGTCGCGGCGACAAGCTGCTCGACGCACCGCTGG
CGAAGATCGGCGGCAAGGGCCTGTTCGTCAAGGAACTGGAAACCGCCCTGCTCGAAGGCGCCGCCGACATCGCGGTGCAT
TCGATGAAGGACGTGCCGATGGACTTTCCCGAGGGGCTCGGCCTCTACACCATCTGCGAGCGCGAAGACCCGCGTGACGC
TTTCGTCTCGAACACCTACGCCAGCCTCGAGCAACTGCCAGCCGGGAGCGTGGTCGGCACCTCCAGCCTGCGCCGCCAGG
CGCAGCTGCTGGCGCGCCGGCCGGACCTGCAGATCCGTTTCCTGCGGGGCAACGTCAATACCCGCCTGGCCAAGCTGGAT
GCCGGCGAATACGACGCGATCATCCTCGCCGCCGCCGGCCTGATCCGCCTCGGCTTCGAGTCGCGCATCCGCTCCTCGAT
CAGTGTCGACGACAGCCTGCCCGCCGGCGGACAAGGCGCCGTCGGCATCGAATGCCGTACGGCCGACAGCGACCTGCATG
CCTTGCTGGAACCCTTGCACCATACCGACACGGCTCTGCGGGTCACTGCCGAGCGCGCGCTGAACAAGCGGCTCAACGGC
GGTTGCCAGGTGCCGATCGCCTGCTACGCCATCCGCGAGGGCGACCAGCTGTGGCTGCGCGGCCTGGTCGGCCAGCCTGA
TGGCACCCAGTTGCTGCGCGCCGAGGGGCGGGCGCCACTGGCGGAAGCCGAGGCGCTGGGCGTGCGGGTGGCCGAGGACC
TGCTGGAGCAGGGCGCCGAAGCGATTCTCGAAGCCGTCTACGGCGAGGCCGGACATCCGTGA

Protein sequence :
MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKGLFVKELETALLEGAADIAVH
SMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLPAGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLD
AGEYDAIILAAAGLIRLGFESRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHTDTALRVTAERALNKRLNG
GCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAEAILEAVYGEAGHP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-67 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-67 61