Gene Information

Name : PLES_54111 (PLES_54111)
Accession : YP_002442989.1
Strain : Pseudomonas aeruginosa LESB58
Genome accession: NC_011770
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 5982488 - 5984104 bp
Length : 1617 bp
Strand : +
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
ATGATCGCCGGCAACGACGGGGTCGGCGGCATCGTCTTCGACAACTATCCGATGGCCTACCTGGTGGGCAACCTGGCGCT
CGCCGTGATCCTCCTCGACGGCGGCCTGCGCACCCGCGTCTCCAGCTTCCGCGTGGCGCTCTGGCCGGCATTGTCGCTGG
CCACCCTGGGCGTGCTGGTGACCACCGGCCTGACCGGCATCGCGGCAGCCTGGCTGTTCGACCTGCACTGGATGGAAGGC
CTGCTGATCGGCGCCATCGTCGGCTCCACCGACGCCGCCGCGGTGTTCTCCCTGCTCGGCGGCAAAGGTCTCAACGAGCG
GGTCACCGCGACCCTGGAAATCGAATCGGGCAGCAACGACCCGATGGCGGTGTTCCTCACCGTGACCCTGATCGAGATGC
TCGCCAGCGGCCAGACCGGCCTCAGCTGGGGCTTCGCCCTGCACCTGGTGCAGCAGTTCGGTCTCGGCGCCCTGCTCGGT
CTTGGCGGCGGCTGGTTGCTGCTGCAACTGATCAACCGCATGCACCTGGCCGGCGGCCTCTACCCGTTGCTGGTGATCAG
CGGCGGCCTGCTGGTGTTCGCCCTGGCCAACGCCGTCGGCGGCAGCGGCATCCTCGCCATCTACCTGTGCGGCCTGCTCC
TCGGCAACCGCCCGATCCGCAGCCGCCACGGCATCCTGCACATGCTCGACGGCATGGCCTGGCTGGCGCAGATCGGCATG
TTCCTGGTCCTCGGCCTGCTGGTCACCCCCCACGACCTGTGGCCGATCGCCCTGCCGGCACTGGCCCTGGCGCTGTGGAT
GATCCTGGTGGCACGACCGCTGTCGGTACTGATCGGACTGATCCCGTTCCGCGCCTTCCACGACCGCGAGAAAGCCTTCA
TCGCCTGGGTCGGCCTGCGCGGCGCGGTGCCGATCATCCTCGCGGTGTTCCCGCTGATGGCCGGCCTGCCGAACGCCCAG
CTGTTCTTCAACGTGGCCTTCTTCATCGTCCTGGTCTCGCTGCTGGTGCAGGGCACCAGCCTGCCCTGGGCGGCCAGGCT
GCTGCGGGTGGTGGTGCCGCCGGATCCGGCACCGATATCCCGCGCCGGCCTGGAGATCCACCCGACCAGCGAGTGGGAGC
TGTTCGTCTACCACCTGAACAAGGAAAAGTGGTGCATCGGCGCCGCCCTGCGCGAGCTGAAGATGCCCGGCGGGACCCGG
ATCGCCGCGCTGTTCCGCGGCACCGAACTGCTCCACCCGTCGGGCAGCACCATCCTCGAGGCCGACGACATTCTCTGCGT
GATCGGCCACGAACACGACCTGCCGGCCCTCGGCAAGCTGTTCAGCCAGGCGCCCGACCGGGGCCTCGGCGCGCGCTTCT
TCGGCGACTTCGTGCTGGAAGGCGATGCCCAGCTGTCGGCGGTGGCCTCGCTCTACGGCCTGAAGCTCGACGGCATCGAC
GGCGAGCAAGCGCTGGGCCGCTTCATCGCCCACGAGATCGGCGGCGAAGCGGTGATCGGCGACCAGGTGGAGTGGAACGG
CCTGACCTGGACCGTGGCCGCCCTGGAAGGCAACCGTATCCGCAAGGTCGGCGTGAAGTTTCCGGAAGGCCGCCCAGGGC
CCGGACTTTTCCTCTGA

Protein sequence :
MIAGNDGVGGIVFDNYPMAYLVGNLALAVILLDGGLRTRVSSFRVALWPALSLATLGVLVTTGLTGIAAAWLFDLHWMEG
LLIGAIVGSTDAAAVFSLLGGKGLNERVTATLEIESGSNDPMAVFLTVTLIEMLASGQTGLSWGFALHLVQQFGLGALLG
LGGGWLLLQLINRMHLAGGLYPLLVISGGLLVFALANAVGGSGILAIYLCGLLLGNRPIRSRHGILHMLDGMAWLAQIGM
FLVLGLLVTPHDLWPIALPALALALWMILVARPLSVLIGLIPFRAFHDREKAFIAWVGLRGAVPIILAVFPLMAGLPNAQ
LFFNVAFFIVLVSLLVQGTSLPWAARLLRVVVPPDPAPISRAGLEIHPTSEWELFVYHLNKEKWCIGAALRELKMPGGTR
IAALFRGTELLHPSGSTILEADDILCVIGHEHDLPALGKLFSQAPDRGLGARFFGDFVLEGDAQLSAVASLYGLKLDGID
GEQALGRFIAHEIGGEAVIGDQVEWNGLTWTVAALEGNRIRKVGVKFPEGRPGPGLFL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 3e-145 67
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 3e-145 67