Gene Information

Name : PLES_36301 (PLES_36301)
Accession : YP_002441215.1
Strain : Pseudomonas aeruginosa LESB58
Genome accession: NC_011770
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 4021180 - 4022502 bp
Length : 1323 bp
Strand : +
Note : -

DNA sequence :
ATGCCCGCGCCTCTCTCTCCTCTCATCGTCCGGATGCGCCACGCCATCGAAGGCTGCCGGCCGATCCAGATCCGCGGGCG
GGTCACCCAGGTCACTGGAACCCTGCTCAAGGCCGTGGTGCCCGGCGTGCGCATCGGCGAACTCTGCCAGTTGCGCAATC
CCGACCAGAGCCTGGCGCTGCTCGCCGAGGTCATCGGCTTCCAGCAGCACCAGGCGCTGCTCACCCCGCTCGGCGAGATG
CTCGGGGTTTCCTCCAACACCGAAGTCAGCCCTACCGGCGGCATGCATCGCGTGGCGGTTGGCGAGCACCTGCTCGGGCG
GGTGCTCGACGGCCTCGGCCGCCCCTTCGACGGCAGCCCGCCGGCCGAGCCGGCGGCCTGGTATCCGGTCTACCGGGATG
CTCCGCCGCCGATGAGCCGGCGCCTGATAGAGCGGCCGCTATCGCTGGGTGTGCGCGCCATCGACGGCCTGCTGACCTGC
GGCGAAGGCCAGCGCATGGGCATTTTCGCTGCCGCCGGCGGCGGCAAGAGCACCCTGCTGGCCAGCCTGGTGCGCAATGC
CGAGGTGGATGTGACGATACTCGCCCTGGTCGGCGAACGCGGTCGCGAAGTCCGCGAGTTCATCGAAAGCGACCTCGGCG
AACAGGGGCTGCGCCGCTCGGTGCTGGTGGTCGCCACCTCCGACCGACCGGCGATGGAGCGCGCCAAGGCCGGTTTCGTC
GCCACCAGCATCGCCGAGTATTTCCGCGATCAGGGTCGCCGCGTCCTGCTGCTGATGGACTCGCTGACCCGCTTCGCCAG
GGCCCAGCGCGAAATCGGCCTGGCGGCCGGTGAACCGCCCACCCGCCGTGGCTACCCGCCATCGGTGTTCGCCGCGCTGC
CACGCCTGATGGAGCGTGCCGGGCAATCCGAGCGGGGCTCGATCACCGCGCTCTACACCGTGCTGGTGGAAGGCGACGAC
ATGAGCGAGCCGGTGGCCGACGAGACCCGTTCGATTCTCGACGGGCACATCGTGCTGTCGCGCAAGCTGGCCGCCGCCAA
CCACTATCCGGCCATCGACGTGCTGCACTCGGTGAGCCGGGTCATGAACCAGATCGTCGACGACGATCAGCGCCATGCGG
CCGGACGCTTGCGCGAATGGCTGGCGAAGTACGAGGAAGTCGAGTTGCTGCTGAAGATCGGCGAATACCAGAAAGGCCAG
GACAGCGAAGCCGACCAGGCCATCGAGAAGATCGGGGCGATCCGCCAGTGGCTGCGCCAGGGTACCCACGAAACCAGCGA
TTACGCACAGGCCTGCGCGCAGTTGCGGAGCCTCTGCGCATGA

Protein sequence :
MPAPLSPLIVRMRHAIEGCRPIQIRGRVTQVTGTLLKAVVPGVRIGELCQLRNPDQSLALLAEVIGFQQHQALLTPLGEM
LGVSSNTEVSPTGGMHRVAVGEHLLGRVLDGLGRPFDGSPPAEPAAWYPVYRDAPPPMSRRLIERPLSLGVRAIDGLLTC
GEGQRMGIFAAAGGGKSTLLASLVRNAEVDVTILALVGERGREVREFIESDLGEQGLRRSVLVVATSDRPAMERAKAGFV
ATSIAEYFRDQGRRVLLLMDSLTRFARAQREIGLAAGEPPTRRGYPPSVFAALPRLMERAGQSERGSITALYTVLVEGDD
MSEPVADETRSILDGHIVLSRKLAAANHYPAIDVLHSVSRVMNQIVDDDQRHAAGRLREWLAKYEEVELLLKIGEYQKGQ
DSEADQAIEKIGAIRQWLRQGTHETSDYAQACAQLRSLCA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-175 83
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-117 62
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-115 62
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-117 62
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-115 62
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-117 62
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-116 62
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 5e-116 62
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-115 61
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-116 61
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-103 57
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-102 56
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-103 55
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-102 55
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-102 55
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-103 55
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 9e-92 54
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 7e-94 54
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 9e-94 53
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-94 53
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-97 53
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 6e-92 52
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-89 52
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-89 52
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 5e-98 51
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-98 51
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 5e-98 51
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-98 51
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-98 51
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 6e-104 50
unnamed AAL06369.1 EscN Virulence LEE Protein 5e-98 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-95 50
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-95 50
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-98 50
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-98 50
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-98 50
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-98 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-98 50
escN AAC38383.1 EscN Virulence LEE Protein 3e-98 50
escN AAK26715.1 EscN Virulence LEE Protein 3e-98 50
escN AAL57542.1 EscN Virulence LEE Protein 3e-98 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-98 50
escN AAC31513.1 L0034 Virulence LEE Protein 3e-98 50
invC AAS66861.1 InvC Not tested SSR-2 Protein 5e-87 48
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-82 46
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 8e-82 46
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-82 46
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-82 46
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 7e-86 46
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-83 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG0192 Protein 0.0 99
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG0390 Protein 4e-170 82
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG0048 Protein 4e-140 68
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG2144 Protein 1e-116 57
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG0515 Protein 2e-102 55
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG0812 Protein 2e-98 50
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG0730 Protein 2e-98 50
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG2459 Protein 2e-86 47
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG1254 Protein 1e-90 47
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG0555 Protein 3e-82 46
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG2499 Protein 2e-80 46
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG2331 Protein 2e-82 45
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG1778 Protein 1e-86 45
PLES_36301 YP_002441215.1 type III secretion system ATPase VFG1008 Protein 7e-84 44