Gene Information

Name : tpx (PLES_27621)
Accession : YP_002440356.1
Strain : Pseudomonas aeruginosa LESB58
Genome accession: NC_011770
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 2968354 - 2968851 bp
Length : 498 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCTCAAGTGACTCTCAAGGGCAACCCGGTCAACGTCGATGGCCAGCTCCCGCAGAAAGGCGCCCAGGCTCCGGCCTT
CAGCCTGGTCGGCGGCGACCTCGCCGACGTGACCCTGGAAAACTTCGCCGGCAAGCGCAAGGTGCTGAACATCTTCCCCA
GCGTCGACACCCCGACCTGCGCCACCTCGGTGCGCAAGTTCAACGTCGAGGCCGGCAAGCTGGCCAACACCGTGGTGCTG
TGCATCTCCGCCGACCTGCCGTTCGCGCAGAAGCGCTTCTGCGGCGCCGAAGGCCTGGAGAACGTAGTCAACCTGTCGAC
CCTGCGCGGTCGCGAGTTCCTCGAGAACTATGGCGTGGCCATCGCCAGCGGCCCGCTGGCCGGCCTGGCCGCGCGCGCCG
TGGTGGTGCTCGACGAGCAGAACAAGGTGCTGCACAGCGAACTGGTCGGCGAAATCGCCGACGAGCCGAACTACGCGGCG
GCCCTGGCGGCTCTCTGA

Protein sequence : 
MAQVTLKGNPVNVDGQLPQKGAQAPAFSLVGGDLADVTLENFAGKRKVLNIFPSVDTPTCATSVRKFNVEAGKLANTVVL
CISADLPFAQKRFCGAEGLENVVNLSTLRGREFLENYGVAIASGPLAGLAARAVVVLDEQNKVLHSELVGEIADEPNYAA
ALAAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 2e-29 48
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-29 48
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-29 48
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-29 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_002440356.1 thiol peroxidase VFG0087 Protein 4e-30 48