Gene Information

Name : kdsB (PLES_20831)
Accession : YP_002439686.1
Strain : Pseudomonas aeruginosa LESB58
Genome accession: NC_011770
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 2256695 - 2257459 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGACCCAGGCGTTCACTGTCGTCATTCCCGCCCGCTACGCCTCCACTCGCCTGCCCGGCAAGCCATTGCAGGATATCGC
CGGCCAGCCAATGATCCAGCGCGTCTGGAACCAGGCCCGCAAGAGCGCCGCCAGCCGCGTGGTCGTCGCCACCGACGACG
AACGCATCCTGGCGGCGTGCCAGGGGTTCGGCGCCGAGGCGCTGCTGACGCGTGCCGAGCACAACTCCGGCACCGATCGC
CTGGAGGAAGTCGCTTCCCGGCTCGGCCTGGCCAGCGATGCCATCGTGGTCAACGTCCAGGGCGACGAACCGCTGATCCC
CCCGGCGCTCATCGACCAGGTGGCGGCCAACCTGGCGGCGCACCCGGAAGCTGCCATCGCTACCCTGGCCGAGCCGATTC
ATGAGGTCTCCGCGCTGTTCAATCCGAACGTGGTCAAGGTCGCCACCGACATCGACGGCCTGGCCCTGACTTTCAGTCGT
GCGCCCTTGCCCTGGGCTCGTGACGCCTTCGCCCGCGATCGCGACAGCCTGCCGGAGGGCGTGCCCTATCGTCGCCACAT
CGGCATCTACGCCTATCGCGTGGGTTTCCTTGCCGATTTCGTCGCCTGGGGACCGTGCTGGCTGGAGAACGCCGAAAGCC
TCGAGCAATTGCGCGCGCTCTGGCACGGGGTGCGAATCCATGTGGCCGATGCCCGCGAAACCATGCTTCCGGGCGTGGAT
ACGCCGGAAGACCTCGAACGCGTTCGCCGCGTGCTGGGGGGCTGA

Protein sequence : 
MTQAFTVVIPARYASTRLPGKPLQDIAGQPMIQRVWNQARKSAASRVVVATDDERILAACQGFGAEALLTRAEHNSGTDR
LEEVASRLGLASDAIVVNVQGDEPLIPPALIDQVAANLAAHPEAAIATLAEPIHEVSALFNPNVVKVATDIDGLALTFSR
APLPWARDAFARDRDSLPEGVPYRRHIGIYAYRVGFLADFVAWGPCWLENAESLEQLRALWHGVRIHVADARETMLPGVD
TPEDLERVRRVLGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 6e-36 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-36 44
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-36 44