Gene Information

Name : PLES_19091 (PLES_19091)
Accession : YP_002439513.1
Strain : Pseudomonas aeruginosa LESB58
Genome accession: NC_011770
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase-like protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2056979 - 2058247 bp
Length : 1269 bp
Strand : +
Note : orf02748

DNA sequence : 
ATGAAGGATCTGAAGGTTGCAGTTGTTGGGCTAGGCTATGTTGGTCTTCCGCTTGCTGTTGAATTTGGTAAAAAACGAAC
CGTTGTCGGTTTCGATATCAATCAGGGGCGAATCGCTGAACTGCGGCAAGGCATTGACTCTACTCTTGAAGTAGATGCGG
CTGAGTTGAAAGAAGCGTCCGAACTGAGCTTTACTTTCAATCTTCAGGACTTGCAAAAGTGCAATGTTTTCATTGTGACG
GTTCCTACACCTATTGATGAACATAAGCAACCCGACCTCACCCCTCTTGTAAAGGCCTCGGAGAGCATCGGAAAGGTTCT
GAAGAAGGGCGATATTGTAATTTATGAGTCTACCGTTTACCCGGGAGCGACGGAAGAAGACTGCGTACCTGTTCTGGAAA
AATTTTCCGGGCTGAGGTTTAACGAGGACTTCTTCGCCGGTTATAGCCCCGAGCGCATCAATCCCGGCGATAAGGAACAT
CGGGTCTCTTCGATCAAGAAGGTCACTTCCGGCTCTACGCCGGAGATCGCGGAGTTGGTTGACTCCCTGTATAGAGAAAT
CATCACTGCCGGTACTCACAAGGCGAGCAGCATTAAAGTCGCTGAGGCTGCCAAGGTGATCGAAAATACGCAGCGAGATC
TCAATATTGCTCTGATCAACGAACTCGCCATCATTTTCAATCGAATGGGTATCGATACCGAGGCGGTCCTCAAGGCTGCC
GGCACGAAATGGAATTTCATGCCGTTCCGCCCGGGCCTAGTCGGCGGTCATTGCATCGGAGTCGATCCATATTATCTGAC
TCATAAAGCCCAGAGTATTGGCTATCATCCAGAGATCATCCTGGCTGGCCGCCGTTTGAATGACGGTATGGGTGCCTATG
TCGTTTCGCAACTGGTCAAGGCTATGCTCAAGCGTCGTATCCACGTGGACGGTGCTCGCGTTCTGCTTATGGGGCTTACA
TTCAAGGAAAATTGTCCAGACCTCCGCAATACCAAAGTCGTCGATATTGTCCGTGAGTTGGCGGAATACAACATACAGGT
TGATGTTTTTGATCCTTGGGTGAGCGCCGAAGATGCCATGCATGAGTATGGGATTACTCCAGTCGGTACGCCATCCCATG
GCGCTTATGATGGAATTATCCTTGCGGTCGCGCACAGTGAATTCAAAAATATGGGCGCAGAAAATATACGAAAGTTAGGG
AAGGCTGAGCATGTTCTCTATGATCTGAAATATCTACTCGATGAAGATAAGTCTGATCTACGCCTGTAA

Protein sequence : 
MKDLKVAVVGLGYVGLPLAVEFGKKRTVVGFDINQGRIAELRQGIDSTLEVDAAELKEASELSFTFNLQDLQKCNVFIVT
VPTPIDEHKQPDLTPLVKASESIGKVLKKGDIVIYESTVYPGATEEDCVPVLEKFSGLRFNEDFFAGYSPERINPGDKEH
RVSSIKKVTSGSTPEIAELVDSLYREIITAGTHKASSIKVAEAAKVIENTQRDLNIALINELAIIFNRMGIDTEAVLKAA
GTKWNFMPFRPGLVGGHCIGVDPYYLTHKAQSIGYHPEIILAGRRLNDGMGAYVVSQLVKAMLKRRIHVDGARVLLMGLT
FKENCPDLRNTKVVDIVRELAEYNIQVDVFDPWVSAEDAMHEYGITPVGTPSHGAYDGIILAVAHSEFKNMGAENIRKLG
KAEHVLYDLKYLLDEDKSDLRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-136 67
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-136 67
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-108 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PLES_19091 YP_002439513.1 UDP-glucose/GDP-mannose dehydrogenase-like protein VFG0431 Protein 7e-137 67