Gene Information

Name : guaA (PLES_12051)
Accession : YP_002438811.1
Strain : Pseudomonas aeruginosa LESB58
Genome accession: NC_011770
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1303436 - 1305013 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCCCAAGACATTCACGCCCACCGTATCCTGATCCTCGATTTCGGCTCCCAGTACACCCAACTGATCGCTCGCCGCGT
GCGCGAGATCGGCGTGTATTGCGAAATCCATCCCTTCGACATGAGCAACGAGGCGATCATCGCCTTCGCGCCGCGCGGCA
TCATCCTCGCCGGTGGCCCCGAGTCGGTACACGAAGCCGACAGCCCGCGCGCGCCGCAGGCGGTGTTCGACCTGAAGGTG
CCGCTGTTCGGCATCTGCTACGGCATGCAGACCATGGCCGAGCAGATGGGCGGCAAGGTGCAGGGCTCCGACCTGCGCGA
GTTCGGCTACGCCCGCGTCGACGTGGTCGGCAAGGCGCGCCTGCTGGACGGCATCGAGGACCACGTGGACGACGACGGCG
TGCTCGGCCTCGACGTGTGGATGAGCCACGGCGACAAGGTCACCGAGATGCCGGCCGGCTTCCACATCCTGGCCAGCACC
CCGAGCTGCCCGATCGCCGCCATGGCCGACGATGCCCGCGCCTACTACGGCGTGCAATTCCACCCGGAAGTCACCCACAC
CAAGCAGGGCCTGCGCATTCTCTCGCGCTTCGTCCTCGACATCTGCGGTTGCGCCGCGCTGTGGACCCCCTCGAACATCG
TCGACGACGCCATCGCCACCGTGCGCGCCCAGGTCGGTTCCTCCAAGGTCCTGCTAGGCCTCTCCGGCGGCGTGGACTCC
TCGGTGGTCGCCGCGCTGCTGCACAAGGCCATCGGCGACCAACTGACCTGCGTGTTCGTCGACAACGGCCTGCTGCGCCT
GCACGAAGGCGACCAGGTGATGGCCATGTTCGCCGAGAACATGGGCGTGAAGGTGATCCGCGCCAACGCCGAGGACAAGT
TCCTCGGCCGCCTGGCCGGCGTCGCCGACCCGGAAGAGAAGCGCAAGATCATCGGCCGCACCTTCATCGAAGTTTTCGAC
GAAGAAGCCACCAAGCTGCAGGACGTGAAGTTCCTCGCCCAGGGCACCATCTACCCCGACGTGATCGAGTCGGCCGGCGC
CAAGACCGGCAAGGCCCACGTGATCAAGTCGCACCACAACGTCGGCGGCCTGCCGGAGGACATGCAGTTCGAACTGGTCG
AGCCGCTGCGCGAACTGTTCAAGGACGAAGTGCGCAAGATCGGCCTGGAGCTGGGCCTGCCCTACGACATGGTCTACCGC
CACCCGTTCCCCGGCCCGGGCCTGGGCGTGCGCATCCTCGGCGAGGTGAAGAAGGAGTACGCCGACCTGCTGCGCCAGGC
CGACCACATCTTCATCGAGGAACTGCGCGCCTTCGACTGGTACCACAAGACCAGCCAGGCGTTCGTGGTGTTCCAGCCAG
TGAAATCGGTCGGCGTGGTCGGCGACGGCCGTCGCTACGCCTGGGTCGTCGCCCTGCGCGCGGTGGAGACCATCGACTTC
ATGACCGCGCGCTGGGCGCACCTGCCCTACGAACTGCTGGAGAAGGTCTCGAACCGCATCATCAACGAGATCGCCGGTAT
CTCCCGGGTCACCTACGACGTGTCGAGCAAGCCGCCGGCGACTATCGAGTGGGAGTGA

Protein sequence :
MSQDIHAHRILILDFGSQYTQLIARRVREIGVYCEIHPFDMSNEAIIAFAPRGIILAGGPESVHEADSPRAPQAVFDLKV
PLFGICYGMQTMAEQMGGKVQGSDLREFGYARVDVVGKARLLDGIEDHVDDDGVLGLDVWMSHGDKVTEMPAGFHILAST
PSCPIAAMADDARAYYGVQFHPEVTHTKQGLRILSRFVLDICGCAALWTPSNIVDDAIATVRAQVGSSKVLLGLSGGVDS
SVVAALLHKAIGDQLTCVFVDNGLLRLHEGDQVMAMFAENMGVKVIRANAEDKFLGRLAGVADPEEKRKIIGRTFIEVFD
EEATKLQDVKFLAQGTIYPDVIESAGAKTGKAHVIKSHHNVGGLPEDMQFELVEPLRELFKDEVRKIGLELGLPYDMVYR
HPFPGPGLGVRILGEVKKEYADLLRQADHIFIEELRAFDWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETIDF
MTARWAHLPYELLEKVSNRIINEIAGISRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 9e-122 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-122 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-122 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-108 49