Gene Information

Name : guaA (DvMF_3125)
Accession : YP_002437529.1
Strain : Desulfovibrio vulgaris Miyazaki F
Genome accession: NC_011769
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 3944298 - 3945845 bp
Length : 1548 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGAAGCACAGACCAAGGTCATCATTATCGACTACGGTTCGCAGGTGACGCAGCTAATCGCCCGTCGCGTGCGCGAGGC
TGGCGTCTACTCCGAAATCCACCCCTGCATCGTCACGGCGGATCAGGTGCGCGCCATGAAGCCCGCCGCCGTCATCCTGT
CCGGCGGCCCGGCCAGCGTGGGCGAGGCCGACGCCCCCACTCTGGAAAAGGGCCTGCTGGAGCTTGGCGTGCCGGTTCTG
GCCATCTGCTACGGCATGCAGCTTCTGGGTCACAACCTGGGCGGCCAGCTGGCCACCTCGGAAACCCGCGAATACGGCCC
CGCCGACCTCACCCTGCTGGGCGACTGCCCGCTGTGGGACGGCATCGACAAGTCCGCCACCACCCGCGTGTGGATGAGCC
ACGGCGACAAGGTCAAGACGCCCCCGCCCGGCTTTGCCGTGGTGGGCCGCACCGCCACCCTGGACGTGGCGGCCATGGCC
GACGACGCCCGCCGCATCTATGCCGTGCAGTTCCACCCCGAAGTGCACCACACCGAGGAAGGCACCCGCATCATCAACAA
CTTCCTGTTCCACGTGGCCAAGCTGAAGGCCGACTGGACCATGTCGTCGTTCGTTGAGCGCGCCATCAAGGAAATGGCCG
AAACCGTGGGCGACCGCCACGTGGTGTGCGCGCTTTCGGGCGGCATCGACTCCACCGTGGTGGCCGTGCTGCTGCACAAG
GCCATCGGCAAGCGCCTGCACTGCATCTTCGTGGACAACGGCGTGCTGCGCCTGAACGAAGGCCAGGAAGTGGTGGACTA
CCTGCGCGAGCACTTCGACCTGAACCTGAAGTACGTGCAGGCCCAGCGCCGCTTCCTCGACAAGCTGGAAGGCGTGGAAG
ACCCCGAGCAGAAGCGCAAGATCATCGGCTACACCTTCATCGAGGTGTTCGACGAGGAAGCGAAAGCCCTTGGCCACGTG
GACTTCCTGGCGCAGGGCACCCTGTACCCCGACGTCATCGAATCGGTGTCGCACAAGGGGCCTTCCGCCGTCATCAAGAG
CCACCACAACGTGGGCGGCCTGCCGGAAAAGATGAACCTGAAGCTCATCGAGCCGCTGCGCGAACTGTTCAAGGACGAAG
TGCGCAAGGTGGCGGGCGAACTGGGCCTGCCGGACTTCATCATCTGGCGCCACCCCTTCCCCGGTCCGGGCCTGGCCATC
CGCGTCATCGGCGAAATCACCGAGGAACGCCTGGACATCCTGCGCAAGGCCGACAAGATCGTGCAGGCCGAGCTGATGTC
CTCCGGCTGGTACCGCAAGGTCTGGCAGGGCTTTGCCGTGCTACTGCCGCTTAAGACCGTGGGTGTCATGGGCGATGGCC
GCACCTACGAGCACGTCATCGCCCTGCGCATCGTGGACAGCGTGGACGCCATGACGGCAGACTGGGCGCGCTTGCCTTCC
GAACTGCTTGAGCGTATTTCGAGCCGGATAATCAACGAGGTGAAGGGCGTGAACCGCGTGGTCTACGACATCTCCTCGAA
GCCGCCGAGCACCATCGAATGGGAATAG

Protein sequence :
MEAQTKVIIIDYGSQVTQLIARRVREAGVYSEIHPCIVTADQVRAMKPAAVILSGGPASVGEADAPTLEKGLLELGVPVL
AICYGMQLLGHNLGGQLATSETREYGPADLTLLGDCPLWDGIDKSATTRVWMSHGDKVKTPPPGFAVVGRTATLDVAAMA
DDARRIYAVQFHPEVHHTEEGTRIINNFLFHVAKLKADWTMSSFVERAIKEMAETVGDRHVVCALSGGIDSTVVAVLLHK
AIGKRLHCIFVDNGVLRLNEGQEVVDYLREHFDLNLKYVQAQRRFLDKLEGVEDPEQKRKIIGYTFIEVFDEEAKALGHV
DFLAQGTLYPDVIESVSHKGPSAVIKSHHNVGGLPEKMNLKLIEPLRELFKDEVRKVAGELGLPDFIIWRHPFPGPGLAI
RVIGEITEERLDILRKADKIVQAELMSSGWYRKVWQGFAVLLPLKTVGVMGDGRTYEHVIALRIVDSVDAMTADWARLPS
ELLERISSRIINEVKGVNRVVYDISSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-136 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-136 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-136 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-125 50