Gene Information

Name : DvMF_2435 (DvMF_2435)
Accession : YP_002436844.1
Strain : Desulfovibrio vulgaris Miyazaki F
Genome accession: NC_011769
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.15
Position : 3070214 - 3071530 bp
Length : 1317 bp
Strand : +
Note : KEGG: lip:LI0540 type III secretion system ATPase; TIGRFAM: ATPase, FliI/YscN family; type III secretion apparatus H+-transporting two-sector ATPase; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; H+transporting two-sector ATPas

DNA sequence :
ATGGCCTTTGAGTATATCGGATCCCTGCTGGAAGAGGCCGTGCACAGCGGCCCCACGGTAGAGGTGCGCGGCCGCGTGGA
GCAGGTGGTGGGCACCATCATCCGGGCCGTGGTGCCCGGCGTGAAGGTGGGCGAGCTGTGCATCCTGCGCAACCCGTGGG
AAAACTGGACCCTGCGGGCCGAGGTGGTGGGCTTCGTCAAGCAGGTGGCCCTGCTGACCCCCCTGGGCGACCTGCAAGGG
GTGTCCCCGGCCACGGAGGTCATACCCACCGGCGAAATCCTGTCCATACCCGTGGGCGAAGACCTGCTGGGCCGCGTGCT
GGACGGACTGGGCGAACCCATGGACGGCGGCCCGCCCCTGAAGCCGCGCACCCGCTATCCCGTCTATGCCCAGCCGCCCA
ACCCCATGCAGCGGCGCATCATCGACCGGCCCATCTCCCTTGGCCTGCGCGTGCTGGACGGGGTGCTCACCTGCGGCGAA
GGGCAACGCATGGGCATTTTCGCGGCGGCGGGCGGCGGCAAGAGCACGCTGCTGTCCAGCATCATCAAGGGCTGCTCGGC
GGATGTGTGCGTGCTGGCCCTTATCGGCGAACGTGGCCGCGAAGTGCGCGAATTCATAGAGCACGACCTGGGGCCTGAAG
GCCGCAAGAAGGCGGTGCTGGTGGTTTCCACCTCGGACAGGTCGTCCATGGAACGCCTGAAGGCCGCCTATACCGCCACG
GCCATTGCCGAATATTTCCGCGACCAGCGCCGCAGCGTGCTGCTGATGATGGATTCCGTGACCCGCTTTGGCCGCGCCCA
GCGCGAGATAGGCCTTGCCGCGGGCGAACCGCCCACGCGGCGCGGCTTTCCGCCGTCGGTGTTCTCCACCCTGCCGCGCC
TCATGGAGCGGGCGGGCAATTCGGACAAGGGGTCCATCACCGCGCTGTACACCGTGCTGGTGGAAGGCGACGACATGACG
GAACCCATCGCCGACGAAACCCGGTCCATCCTCGACGGGCACATCGTGCTTTCGCGCAAGCTGGCCGCCGCCAACCACTA
TCCGGCCATCGACGTGCAGGCCAGCGTCAGCCGCGTCATGAACGCCATCGTGGACAAGGAGCACAAGGCCGCTGCGCAAA
AGCTGCGAAAGGTGCTGGCCAAGTACGCCGAAGTGGAGTTGCTGGTGCAGATCGGCGAGTACAAGCGCGGGTCGGACAAG
GAAGCGGACGAGGCGCTGGACCGGGTGGCCGCGGTCAACGCCTTCCTGCGCCAGGGGCTGGACGAGCGCAGCGGGTTCGA
TGACACGCTGGCCGCCCTGCGCAAGGTGGTGGAATAG

Protein sequence :
MAFEYIGSLLEEAVHSGPTVEVRGRVEQVVGTIIRAVVPGVKVGELCILRNPWENWTLRAEVVGFVKQVALLTPLGDLQG
VSPATEVIPTGEILSIPVGEDLLGRVLDGLGEPMDGGPPLKPRTRYPVYAQPPNPMQRRIIDRPISLGLRVLDGVLTCGE
GQRMGIFAAAGGGKSTLLSSIIKGCSADVCVLALIGERGREVREFIEHDLGPEGRKKAVLVVSTSDRSSMERLKAAYTAT
AIAEYFRDQRRSVLLMMDSVTRFGRAQREIGLAAGEPPTRRGFPPSVFSTLPRLMERAGNSDKGSITALYTVLVEGDDMT
EPIADETRSILDGHIVLSRKLAAANHYPAIDVQASVSRVMNAIVDKEHKAAAQKLRKVLAKYAEVELLVQIGEYKRGSDK
EADEALDRVAAVNAFLRQGLDERSGFDDTLAALRKVVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 6e-131 68
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-110 61
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-111 61
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-111 61
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-111 61
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-110 61
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 8e-111 61
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-111 61
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-109 60
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-109 60
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-102 57
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-90 52
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 5e-90 52
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-90 52
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-90 52
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-90 52
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-94 52
escN AAL57542.1 EscN Virulence LEE Protein 2e-94 52
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-94 52
escN CAI43874.1 EscN protein Virulence LEE Protein 8e-95 52
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-94 52
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-95 52
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-94 52
escN AAC38383.1 EscN Virulence LEE Protein 2e-94 52
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-94 52
escN AAC31513.1 L0034 Virulence LEE Protein 2e-94 52
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-94 52
escN AAK26715.1 EscN Virulence LEE Protein 2e-94 52
unnamed AAL06369.1 EscN Virulence LEE Protein 7e-93 52
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 6e-87 51
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-92 51
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-92 51
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-80 51
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-87 51
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-87 51
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-85 50
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 9e-86 50
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 5e-86 50
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-86 50
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-81 50
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-81 50
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-89 50
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 7e-92 49
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-80 47
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-80 47
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-79 46
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-79 46
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-79 46
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 6e-79 46
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 6e-80 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG0390 Protein 3e-136 70
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG0192 Protein 2e-134 68
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG0048 Protein 3e-138 67
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG2144 Protein 4e-112 58
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG0515 Protein 1e-90 52
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG0812 Protein 1e-94 52
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG0730 Protein 1e-94 52
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG2459 Protein 1e-87 49
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG2331 Protein 1e-80 49
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG1254 Protein 1e-86 49
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG2499 Protein 6e-80 47
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG0555 Protein 3e-79 46
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG1778 Protein 9e-81 45
DvMF_2435 YP_002436844.1 type III secretion system ATPase VFG1008 Protein 5e-79 44