Gene Information

Name : guaA (Dalk_0117)
Accession : YP_002429295.1
Strain : Desulfatibacillum alkenivorans AK-01
Genome accession: NC_011768
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 168950 - 170479 bp
Length : 1530 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGATAATTATTATAGACTTCGGATCCCAATACAACCAGTTAATAGCCCGCCGCGTGAGAGAGCACAAGGTGTTCTGCCA
AATAGAGCCGCCCACGCTGACTGTGGAAAAGGTCAAGTCCCTTGCGCCGGACGGCATCATCCTGTCCGGCGGGCCGGCCA
GCATCTATTCCGAAAACAGCCCCAAAATCGATCCCGAATTATTGAACCTGGGCATCCCGGTTCTGGGCATCTGCTACGGC
CTGCAATTCATGGTGCACACCCAGGGCGGCAAGGTGGAAAGGGCGGACAAGCGGGAATACGGCCTGGCCATGTTCCATCC
CAAAGAAGCGGCCGGCTTGTTCGAAGGCGTGCCTGAAGCCACCGAATGCTGGATGAGCCACGGAGATTCAATCAAAGAGC
TGCCCGAGGGATTTGTCATCACCGGTTCCACGGACAACACCAAGGTGGCGGCTATCGCCCATAAAAAGAAAAAGCTGTTC
GGGCTGCAGTTTCACCCGGAAGTCACCCACACGCCCAAGGGCAAACGCATGCTGAAAAATTTTCTTTTCAATGTGTGCGA
TTGCAAACGCAACTGGACCATGAAATCCTTTGTGAAGGAAGCCGTGGACGAAATCAAGGAGGCCGCCGGCGACGACAAGG
TGATCCTGGGCCTGTCCGGCGGCGTGGACTCCTCAGTGGCGGCCGTACTCATTCATAAGGCCATCGGCAAAAACCTGTAT
CCCATTTTTGTGGATAACGGCCTTTTGAGAAAAGGCGAAGCCGACCGCCTCAAAGAGGTCTTCACCCAAAACCTGAATAT
GAAGGTCCGCTACGCCAAGGCCTCGCGCAAATTCCTGTCCGGCCTTAAAGGGGTCACGGACCCGGAAAAGAAACGCAAGA
TCATCGGCAAGGTTTTTATGGACGTGTTCGAGGAAGAAGCCAAGAAAATCAAGGGCGCCAAATTCCTCGCCCAAGGCACC
CTGTACCCGGACATCATAGAGTCCGTGTCCGCTTTCGGCGGTCCTTCCGCGGTGATCAAAAGCCACCACAACGTGGGCGG
CCTGCCTAAAAAAATGAAGCTCAAGCTCATTGAGCCCCTCAAGTACCTGTTCAAGGACGAAGTAAGGCTTTTGGGCGAGG
AACTGGGCCTGCCCGGCGACATGGTCTGGAGGCAGCCCTTCCCCGGCCCCGGCCTGGCCATCCGGGTCATCGGCGAGGTC
ACGGCCAAAAGACTCAGCATCCTGCGTGAGGTGGACGCCCTGATTATAGAAGAAATCAGGAAAAACGATTACTACCGCAA
GCTGTGGCAATCCTTCGGCGTGCTGCTGCCCATTAAGAGCGTAGGCGTTATGGGGGATCAACGCACTTACGAGAACATCA
TCGCCATCCGCGCGGTCACAAGCACGGACGCCATGACCGCCGACTGGGCCAGGCTGCCCCACGACATGCTGGCAGTCATG
TCCAATAGAATCATCAACGAAATAAACGGAGTCAACCGGGTGGTCTACGACATCAGCTCCAAGCCGCCCAGCACCATCGA
ATGGGAGTAA

Protein sequence :
MIIIIDFGSQYNQLIARRVREHKVFCQIEPPTLTVEKVKSLAPDGIILSGGPASIYSENSPKIDPELLNLGIPVLGICYG
LQFMVHTQGGKVERADKREYGLAMFHPKEAAGLFEGVPEATECWMSHGDSIKELPEGFVITGSTDNTKVAAIAHKKKKLF
GLQFHPEVTHTPKGKRMLKNFLFNVCDCKRNWTMKSFVKEAVDEIKEAAGDDKVILGLSGGVDSSVAAVLIHKAIGKNLY
PIFVDNGLLRKGEADRLKEVFTQNLNMKVRYAKASRKFLSGLKGVTDPEKKRKIIGKVFMDVFEEEAKKIKGAKFLAQGT
LYPDIIESVSAFGGPSAVIKSHHNVGGLPKKMKLKLIEPLKYLFKDEVRLLGEELGLPGDMVWRQPFPGPGLAIRVIGEV
TAKRLSILREVDALIIEEIRKNDYYRKLWQSFGVLLPIKSVGVMGDQRTYENIIAIRAVTSTDAMTADWARLPHDMLAVM
SNRIINEINGVNRVVYDISSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-142 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-142 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-142 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-121 48