Gene Information

Name : DKAM_0008 (DKAM_0008)
Accession : YP_002427704.1
Strain : Desulfurococcus kamchatkensis 1221n
Genome accession: NC_011766
Putative virulence/resistance : Unknown
Product : carbamate kinase-like carbamoyl phosphate synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0549
EC number : -
Position : 5764 - 6753 bp
Length : 990 bp
Strand : +
Note : this enzyme from Pyrococcus has carbamoyl phosphate synthetase activity even though the enzyme shows sequence and structural similarity to carbamate kinase; this enzyme using carbate and ATP to synthesize carbamoyl phosphate which may be a favorable react

DNA sequence :
TTGGAGGGTAAGAGCCATATGAAGAAAGGACTGGATACAATAGTAATAGCGTTAGGAGGAAACGCATTCCAGACCAAAGG
AGACAGAGGCGTGGCCGAGGACTATTGGAGAAATGCCTATACTGTCGCAGAACTTATAGCGAGACTCATCGAGGAAAACT
ATGGCGTCGTAGTGACGCATGGTAACGGCCCACAAGTAGGTATAATCGCGGAATGGATGAGCCTAGGGTTAAAGGAGAAG
AACATACCACCGATGCCCCTTGATGTAGCCGGTGCCATGAGTCAGGGATGGCTTGGCTACATGCTACAGCAGGCTTTATA
TAATAAGCTAGCCGAGAAGAAGCTACTTGGTTCCAAGGTAAGGGGAGTATTAACCATTATCACACAGACGCTTGTAGATA
GGAATGATCCAGCCTTCAATGATCCAACAAAGTACATAGGTCCATGGTATAGCAAGGAGGAAGCTGAAAAATTATCGAGA
GAACTTGGCTGGGTATTTAAACCAGATCCACGCGGTGGGTATAGGAGGGTTGTGCCATCCCCAGATCCCATAGGCCAGAT
TGAGATAGATGCCATTAAGATGCTAGTTGAGCAGGGATTCATCGTGATAGCTGATGGAGGCGGGGGAATACCTGTATACA
GAGATGAAAATGGCTTATTACATGGATTAGAGGGTGTGATAGATAAGGATCTCGGCGCGGAGAGAATGGCTTCGGCGTTG
AAGGCGGATATATTATTAATATTGACAGATATCGAGAAGGCATTTCTAAACTATGGAACACCAAATGCTAAACCCCTTGA
CGTGGTAAAGGTTAGCGAGGCATTAAAATACTATAGGGAAGGACACTTCAAGCCAGGGAGCATGGGTCCAAAAATACTTG
CCGGGATGAGATTCGTCCAAAACGGGGGTAAGATGGCTGTAATAGCTCATTTGAAGCAGGCTTATGAAGCGTTAAAAGGG
AATGCTGGTACAAGAATAATACCTGACTAA

Protein sequence :
MEGKSHMKKGLDTIVIALGGNAFQTKGDRGVAEDYWRNAYTVAELIARLIEENYGVVVTHGNGPQVGIIAEWMSLGLKEK
NIPPMPLDVAGAMSQGWLGYMLQQALYNKLAEKKLLGSKVRGVLTIITQTLVDRNDPAFNDPTKYIGPWYSKEEAEKLSR
ELGWVFKPDPRGGYRRVVPSPDPIGQIEIDAIKMLVEQGFIVIADGGGGIPVYRDENGLLHGLEGVIDKDLGAERMASAL
KADILLILTDIEKAFLNYGTPNAKPLDVVKVSEALKYYREGHFKPGSMGPKILAGMRFVQNGGKMAVIAHLKQAYEALKG
NAGTRIIPD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2636 YP_859422.2 carbamate kinase Not tested Not named Protein 6e-43 43
arcC1 YP_186045.1 carbamate kinase Not tested vSa¥ã Protein 5e-50 42
MW1051 NP_645868.1 carbamate kinase Not tested vSa¥ã Protein 5e-50 42
SAV1170 NP_371694.1 carbamate kinase Not tested vSa¥ã Protein 5e-50 42
SA1013 NP_374286.1 carbamate kinase Not tested vSa¥ã Protein 5e-50 42
arcC YP_493761.1 carbamate kinase Not tested vSa¥ã Protein 5e-50 42
SAKOR_01091 YP_008491279.1 Carbamate kinase Not tested vSa¥ã Protein 5e-50 42
SE0102 NP_763657.1 carbamate kinase Not tested SCCpbp4 Protein 6e-47 41