Gene Information

Name : hemC (AFE_3300)
Accession : YP_002427653.1
Strain : Acidithiobacillus ferrooxidans ATCC 23270
Genome accession: NC_011761
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2974779 - 2975699 bp
Length : 921 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCCGCACTCCCTTCGCATTGGTACCCGTGCCAGCCCGCTGGCCGTCTGGCAGGCAGAGCACGTCCGCGCCGCCCTGTT
GCGGCTTCACCCAGGGATGGCGGTCGAGATCATCACCATGACCACCAGCGGCGACGTTCTTCTGGATGCACCTCTGCATG
CGCTGGGGGGTAAGGGCCTCTTCGTCAAGGAAATCGAAGATGCCCTGCAGCAGCGGCGGGTGGATGTCGCCGTGCACTCC
ATGAAGGATGTGCCGGCGCTACAGCCGGATGGTCTGGAAATCGTCGCCATCATGGCCCGGGAGGATGTCCGGGATGCTTT
CGTCAGCAATACCTTTCTGCATCCCGATGCCCTGCCGGAGGGCGCACGGGTGGGAAGCTCCAGCCTGCGGCGGCGGGCGC
AATTACTGGAGCGCTACCCTCATTTGCGGGTCGAGGACCTGCGCGGCAATGTCGCTACGCGCCTGCGTAGGCTGGACGAG
GGGCATTATGACGCGATCATTCTCGCCGCTGCGGGCCTAAAACGCCTTGGTTTGCCCGATCGCATCACCCATCTGCTGGA
TATCGACCGCTCTCTGCCGGCGGTGGGGCAAGGGGCCATAGGCATCGAGGCGCGCAGCGACGATCGGCGGACCCGGGAAC
TGCTGGCCCCCCTGGCCGACGCCGATACCCAGAACTGCGTGCTGGCGGAGCGCAGCATGAATCAGGTGCTGGGCGGGGAC
TGCCGGCTCCCGGTGGCGGCGCTCGCCCGATGGCAGGGGCCGCAGATGCTCCTGCGCGGGCTGGTCGCCACCCCGGATGG
GCGCCGGGTACTGCATGCCGAGGCGAAGGGCAGCGACCCCGTCGCCCTGGGCATGGCCGTCGCTGCGGCCTTGGTCGCGC
AAGGGGCGGCAGAGATTATCGAGGACGTCCGGAACGCATGA

Protein sequence :
MPHSLRIGTRASPLAVWQAEHVRAALLRLHPGMAVEIITMTTSGDVLLDAPLHALGGKGLFVKEIEDALQQRRVDVAVHS
MKDVPALQPDGLEIVAIMAREDVRDAFVSNTFLHPDALPEGARVGSSSLRRRAQLLERYPHLRVEDLRGNVATRLRRLDE
GHYDAIILAAAGLKRLGLPDRITHLLDIDRSLPAVGQGAIGIEARSDDRRTRELLAPLADADTQNCVLAERSMNQVLGGD
CRLPVAALARWQGPQMLLRGLVATPDGRRVLHAEAKGSDPVALGMAVAAALVAQGAAEIIEDVRNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-66 55
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-66 55